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Wojtovich Lab

Mitochondrial Physiology and Hypoxic Stress Signaling

Mitochondria play a central role in stroke outcomes. We study ischemia reperfusion injury in neurons using optogenetic tools to control the mitochondrial membrane potential or reactive oxygen species production. Depending on where, when, and how mitochondrial function changes, damage or protective signaling can occur. We use CRISPR/Cas9, C. elegans genetics, primary neurons, and measures of mitochondrial bioenergetics to learn about the mechanisms of this damage or protection in our models.

Our laboratory is always looking for new mitochondriacs! Join our dynamic team.
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Andrew P. Wojtovich, Ph.D.

Andrew P. Wojtovich, Ph.D.
Principal Investigator

Publications

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February 3, 2025
Fish, Mercury, and the Developing Brain

October 8, 2024
Pete and Annika win poster prizes at TriMAD – Congrats!

October 7, 2024
TRiMAD Mitochondria Conference comes to Rochester

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Contact Us

  Wojtovich Lab
575 Elmwood Ave, Box 711/604
Rochester, NY 14642