Current Clinical Studies The faculty of Obstetrics and Gynecology regularly conduct clinical research on new devices and medications that may assist in the future health of women. Scroll down to see what we're studying and how you can participate. Studies for Pregnant Women Comparison of gabapentin and metoclopramide in the treatment of hyperemesis gravidarum About the study: Double-blind clinical trial enrolling pregnant women who have received intravenous fluids and have not had much benefit with previous treatments for nausea and vomiting. Study participants will be randomly assigned to take gabapentin (Neurontin) or metoclopramide (Reglan). Click here for more information. Enrolling: Yes PI: Loralei Thornburg, MD Contact: Heather Fiore, MS Ed, RD, CDE 585-275-9165 Studies of Polycystic Ovarian Syndrome Prenatal Androgens and PCOS About the Study: We are recruiting women with polycystic ovary syndrome (PCOS) for a study on whether PCOS might be related to hormones circulating in mothers’ bodies during pregnancy. The study involves a one-time visit similar to a gynecological exam. Blood draw optional. Payment up to $40.00 for completion of study. Enrolling? Yes PI: Emily Barrett, PhD Contact: Lynda Kochman, RN, CCRC 585-275-4149, 585-273-2995 firstname.lastname@example.org ADAPT (PCOS) Study About the Study: The purpose of this study is to determine whether or not treatment of PCOS with hormonal contraception, either in the form of Mirena-IUD, Nexplanon or oral contraceptive pills affects levels of depression and anxiety in women with PCOS compared to those who choose no hormonal treatment for PCOS. This is a survey-based study, and no payment is provided. PI: Kathleen Hoeger, MD, MPH and Snigdha Alur, MD Enrolling? Yes Contact: Lynda Kochman, RN, CCRC 585-275-4149, 585-273-2995; Shaya Greathouse, 585-275-3565. Studies of Other Conditions Global Endometrial Ablation Prospective Data Study About the Study: This study aims to develop a database of information about women undergoing the Novasure endometrial ablation procedure. Subjects enrolled in this study will be asked to complete a series of questionnaires before they undergo the Novasure procedure, 6 months after the procedure, and every year after the procedure for three years. The main purpose of the study is to gain a better understanding of the long term effects of the Novasure ablation. Enrolling? Yes PI: Bala Bhagavath, MD Contact: Divya Kumar, MPH 585-275-9204 GeneXperts About the Study: Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by Xpert ½ Assay, Routine PCR, and Culture. This study will see whether herpes simplex virus can reliably be detected in pregnant women at the time of their delivery. Subjects should have no active herpes lesions at enrollment, and at delivery a vaginal swab and a small blood sample will be collected. Payment for completion is $20. Sponsored by National Institutes of Allergy and Infectious Disease Enrolling? Yes PI: Mary Caserta, MD Contact: HIllary Rich, 585-275-3565 A current list of open clinical trials at the University of Rochester is available here.