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URMC / Obstetrics & Gynecology / Research / Maternal-Fetal & Perinatal Medicine Research

 

Maternal-Fetal and Perinatal Medicine Research


Evaluation of viral (VSV) infection in a whole placental exmount (Dr. Olson-Chen’s MFM thesis work)
Title: Gestational age differences in susceptibility of the human placenta to viral infection
Advisor: Shawn Murphy, PhD

In addition to the broad range of research available at the University of Rochester, the MFM division is active in both basic science and clinical research.

Much of the research is in collaboration with other divisions and departments, and we take a broad, team based approach to most research questions.

Learn more about some of the areas of active Maternal-Fetal and Perinatal Medicine research below, and learn more each faculty member’s and fellow’s area of interest on their profile pages.

Some of the active areas of research of the faculty & fellows in Maternal-Fetal medicine and selected abstract/articles include:

Viral Infection of the Placenta & Immunology of Pregnancy

  • Olson-Chen, C.; Balaram, K.; Hackney, D. "Chlamydia trachomatis and adverse pregnancy outcomes: meta-analysis of patients with and without infection". Maternal and Child Health Journal. 2018; : 1-10.
  • Olson-Chen C, Thornburg LL, Hackney DN. "Does increased peripheral C-reactive protein predate the occurrence of a short cervical length?" The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.. 2014 Jul 0; 27(11):1138-41. Epub 2013 Oct 24.

Preterm Birth, Preterm Rupture of Membranes

Maternal Obesity & Diabetes

Substance Use Disorders in Pregnancy

Nutrition & Environmental Exposures in Pregnancy

Ultrasound Evaluations of the Uterus and Fetus

  • Toscano M; Grace D; Pressman EK; Thornburg LL. "Does transvaginal ultrasound at 13-15 weeks improve anatomic survey completion rates in obese patients?". Journal of Maternal-Fetal and Neonatal Medicine. 2019; 23: 1-7.
  • Zozzaro-Smith P, Gray LM, Bacak SJ, Thornburg LL. "Limitations of Aneuploidy and Anomaly Detection in the Obese Patient." Journal of clinical medicine. 2014 Jul 17; 3(3):795-808. Epub 2014 Jul 17.
  • Ho, M. "Evaluation of suspected fetal skeletal dysplasia for the referring physician". Ultrasound Clinics. 2013; 8: 31-38.
  • Lynch TA; Glantz JC; Drennan K. "Prenatal Prediction of Difficult Intubation in Periviable Neonates Using Standard Fetal Biometric Parameters". American Journal of Perinatology. 2019; 36(6): 594-599.
  • Lynch TA, Szlachetka K, Seligman NS. "Ultrasonographic Change in Uterocervical Angle is not a Risk Factor for Preterm Birth in Women with a Short Cervix." American journal of perinatology.. 2017 Sep 0; 34(11):1058-1064. Epub 2017 Jun 05.

Perinatal Epidemiology, Perinatal Quality

  • Glance LG, Glantz JC, Stevens TP, Faden E, Kreso MA, Pyne SG, Wissler RN, Fichter J, Gloff MS, Dick AW. "Measuring Childbirth Outcomes Using Administrative and Birth Certificate Data". Anesthesiology. 2019; ePub ahead of print.
  • Kacica MA; Glantz JC; Xiong K; Shields EP; Cherouny PH. "A Statewide Quality Improvement Initiative to Reduce Non-Medically Indicated Scheduled Deliveries". Maternal Child Health Journal. 2017; 21(4): 932-941.
  • Glance LG, Dick AW, Glantz JC, Wissler RN, Qian F, Marroquin BM, Mukamel DB, Kellermann AL. "Rates of major obstetrical complications vary almost fivefold among US hospitals." Health affairs.. 2014 Aug 0; 33(8):1330-6.

Selected Publications & Presentations from the 2019/2020 Academic Year

Society for Maternal-Fetal Medicine Annual Meeting, February 2020, Grapevine, TX

Oral Presentations

  • Hollenbach, SJ; Gray L; Pressman EK; Drennan K; "Detecting the Maternal in Morality: A Data fusion Approach to improving pregnancy-associated mortality ascertainment".

Poster Presentations

CREOG & APGO Annual Meeting, February 2020, Orlando, FL 

  • Kaufman L, Dermady K, Seligman N, Garry D, Gilchrist K, Leonard C. A collaborative, multidisciplinary approach to curricular development in addressing the opiate crisis- tools to apply now and design approach to apply later.

Accreditation Council for Graduate Medical Education Annual Educational Conference, February 2020, San Diego, CA

  • ​​Olson-Chen C, Lynch K, Thornburg L. Ob/Gyn fellowship research boot camp improves baseline knowledge.

Society for Reproductive Investigation Annual Meeting, March 2020, Vancouver, British Columbia, Canada

Poster Presentations

  • Marinescu PS, Miller LA, Young RC, Adair D, Hern B, Pressman EK, Seligman NS. Uterine Electromyography:  Novel Uterine Bioelectrical Signalling Patterns Lead To Advances In Understanding of Uterine Contractile Activity.  
  • Marinescu PS, Young RC, Adair D, Hern B, Galas E, Pressman EK, Seligman NS.  Uterine Simulation Index:  A Promising Technique for the Personalized Use of Oxytocin. 
  • Marinescu PS, Young RC, Adair D, Hern B, Pressman EK, Seligman NS.  Contraction Synchronization Predicts the Onset of "True" Labor. 
  • Stefanie J. Hollenbach, M.D., M.S., Jihye Baek, Loralei Thornburg MD, Helen Feltovich MD, MS, Richard K. Miller, PhD, Kevin Parker, PhD, Stephen McAleavey, PhD. H-Scan Imaging of Placental Tissue Demonstrates Potential for Disease State Discrimination.
  • Ahern N, Dermady K, Garry D, Kaufman L, Dreyer D, Kacica M, Leonard C, Yukhayev, A, Seligman NS. Knowledge May Not be the Barrier to Care for Pregnant Women with Opioid Use Disorder: The ACOG District II Education "Bundle”.
  • Olson-Chen C, Chen Y. Financial strain and gestational age at delivery: a pathway analysis.

Oral Presentations

  • Hollenbach, Cochran, Waldrop, Abbott, Harrington. Fetal Rh Antigen is Present Consistently Throughout Cells in the Maternal Circulation in Early Pregnancy.  
    • Winner of SRI President’s Presenter’s Award, which recognizes the 25 most meritorious abstracts submitted by individuals still in training