Skip to main content
Explore URMC


microarryteamUR Medicine Microarray Laboratory is helping to deliver Microarray CGH in the most effective manner possible. We provide access to a complete range of microarray CGH testing (postnatal, prenatal and cancer) in an environment staffed by doctors who are recognized as leaders in their fields.

UR Medicine Labs is the first clinical laboratory to be granted a permit by the New York State Department of Health’s Clinical Laboratory Evaluation Program to run Microarray CGH testing as an approved test. We are also part of the International Standard Cytogenomic Array Consortium (ISCA).

  • We are staffed by knowledgeable NYS licensed Clinical Laboratory Technologists with extensive training in molecular genetics.
  • We are supported by a skilled cytogenetics laboratory that performs traditional karyotyping and Fluorescent In Situ Hybridization (FISH) on prenatal, postnatal and cancer specimens.
  • We offer competitive pricing for Microarray CGH analysis that includes FISH confirmation of positive findings and parental FISH confirmations, if needed.

Our Technology

  • Our Microarray CGH Laboratory uses a custom-designed oligonucleotide-based chip designed by  ClinGen (formerly ISCA Consortium) using a commercial platform (Agilent Technologies, USA) and contains approximately 110,712 oligonucleotides (60mers) that represent coding and non-coding human DNA sequences in the genome along with 59,647 SNPs.
  • We also use chips designed by Cancer Genomics Consortium (formerly CCMC) for cancer. By covering more gene regions in all 46 chromosomes, our microarray CGH and CGH-SNP tests provide a more comprehensive analysis than traditional cytogenetics and FISH.
  • Microarray CGH analysis can detect more than 500 microdeletion/microduplication syndromes.
  • Microarray CGH and CGH-SNP analysis will not detect balanced translocations, inversions, smaller imbalances, point mutations, or low level mosaicism (usually 25-30%) that may underlie the clinical presentation of the patient.
  • This assay also detects regions of homozygosity (ROH) which may raise a suspicion of consanguinity or familial relationships.
  • All abnormal array CGH findings will be confirmed by standard chromosome or FISH analysis. Parental studies and additional assays may be necessary to characterize and interpret the clinical significance of arrayCGH+SNP results.

Our Team

  • M. Anwar Iqbal, Ph.D., FFACMG,Director of Microarray CGH Laboratory and Associate Director of the Cytogenetics Laboratory
  • Mary Shaver, Supervisor, Microarray CGH Laboratory

Contact Us

For more information or to submit samples for testing, contact us at (585) 758-0494.

Samples may be submitted through multiple draw stations located throughout Rochester, by courier services from some outlying hospitals and by FedEx using our prepackaged supplies.

The laboratory has a technologist on-call 24 hours, 7 days a week to answer any questions or concerns.