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Research

The Cardiology Division offers a wide range of research projects to our fellows. We have outstanding clinical research opportunities. We are the home to the world's most successful sudden death arrhythmia research group, the Heart Research Follow-up Program. This research team leads the MADIT series of trials and other leading clinical studies in devices which treat lethal arrhythmias and conduction system defects.

The Cardiology Division also offers basic research within the Aab Cardiovascular Research Institute (CVRI). A wide range of basic science projects are available at the CVRI, including research into vascular biology, heart failure, and ion channels. The CVRI also is home to the URMC Howard Hughes Medical Institute (HHMI) Med-into-Grad Graduate Program for translational biomedical research.

View our Division research pages.

Research Spotlight

“Code Blue” Equals Lower Survival for Cancer Patients

Tuesday, August 01, 2017

Jeffrey BruckelPatients with advanced cancer who suffer cardiac arrest in the hospital have a survival rate of less than 10 percent—half the rate of other patients without cancer, according to a nationwide study led by the University of Rochester Medical Center.

The data helps to clear up some myths in medicine about cardiac arrest survival and can be used as a guidepost when hospitalized cancer patients and their families consider do-not-resuscitate (DNR) orders, said Jeffrey T. Bruckel, M.D., a third-year postdoctoral fellow in cardiology at URMC, who led the research.

“We’re hopeful that our study in some way will help doctors and cancer patients make more informed decisions about the end of life,” Bruckel said. “It’s very important to have early, frank, discussions around the goals of care.”

The study was published by the Journal of Oncology Practice in a special end-of-life care edition.  

Read Full Article

Fellow Research

2017

Miller EO, Krishnamoorthy VK, Ling, FSK, Chaturvedi A, Cameron SJ. A man with chest pain and acute ST elevations on electrocardiogram. BMJ 2017 May 18;357. PMID: 28522610

Morris J, Mix D, Cameron SJ.  Medical management of Acute Aortic Syndromes. Current Treatment Options in Cardiovascular Medicine. Curr Treat Options Cardiovasc Med. 2017 Apr;19(4).  PMID: 28332098

Miller E, Schwartz R. Cardiovascular Risk Assessment with Regadenoson SPECT MPI in Patients with End-Stage Renal Disease is Safe, Effective, and Well Tolerated: Does it Matter? The Journal of Nuclear Cardiology. 2017 Feb;24(1):119-121. PMID: 26626782 

2016

Miller E, Malhotra S, Schwartz R. Quantitative Radionuclide Assessment of Cardiac Dyssynchrony: Breakthrough in Patient Selection for Cardiac Resynchronization Therapy for Refractory Heart Failure? Journal of Nuclear Medicine. 2016 Dec;57(12):1840-1842. PMID: 27754903

Clay RD, Lee EC, Kurtzman MF, Dversdal RK. Teaching the Internist to See: Effectiveness of a 1-day Workshop in Bedside Ultrasound for Internal Medicine Residents. Crit Ultrasound J. 2016 Dec; 8(11). PMID: 27515967.

Howell EH and Cameron SJ Neprilysin inhibition: a brief review of past pharmacological strategies for heart failure treatment and future directions. Cardiol J. 2016 Sep 26. PMID: 27665860

Miller E, Eichelberger J. Adult Congenital Heart Disease and Pregnancy: Discussion, Clinical Case Study, and Fetal Heart Rate Interpretation. periFACTS OB/GYN Academy. 2016 February.

2015

Cameron SJ, Ture SK , Modjeski KL, Mickelsen D, Chakrabarti E, Seaberry M, Field DJ, Le N, Abe J, Morrell, CN. Platelet ERK5 is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion. Circulation. 2015 Jul 7;132(1):47-58. PMID: 25934838.

Cameron, SJ. Vascular Medicine: the eye cannot see what the mind does not know. Journal of the American College of Cardiology. 2015 Jun 30;65(25):2760-3.

Cameron SJ, Laskurain E,  Holcman K,  Richeson JF, Mieszczanska H.  Treacherous Travelers: thrombi.  American Journal of Medicine. 2015 Jul;128(7):695-8

Cameron SJ, Usama D, Block R. A case of abdominal pain with dyslipidemia: difficulties diagnosing cholesterol ester storage disease Eur Rev Med Pharmacol Sci. 2015 Jul;19(14):2628-33.

Fernandez G, Cameron SJ, Nayda J, Cove C.  A Family of Aortic Dissections.  2015 Jul 6. American Journal of Medicine.

Cameron SJ, Laskurain E,  Holcman K,  Richeson JF, Mieszczanska H.  Treacherous Travelers: thrombi.  American Journal of Medicine. 2015 Jul;128(7):695-8. PMID: 25747190

Cameron SJ, Usama D, Block R. A case of abdominal pain with dyslipidemia: difficulties diagnosing cholesterol ester storage disease Eur Rev Med Pharmacol Sci. 2015 Jul;19(14):2628-33.

2014

Gardner B,  Ling, FL Hopke PK, Frampton MW, Utell MJ, Zareba W, Cameron SJ, Chalupa D, Kane C, Kulandhaisamy S, Topf M, Rich, DQ. Ambient fine particulate air pollution triggers ST-elevation myocardial infarction, but not non-ST-elevation myocardial infarction: a case-crossover study.  Part Fibre Toxicol. 2014 Jan 2;11(1):1.  PMID: 24382024

Holcman K, Cameron SJ, Laskurain E, Massey HT, Trawick DR and Mieszczanska H.  Breathtaking: platypnea-orthodeoxia syndrome. American Journal of Medicine. 2014 Jun;127(6):491-3. PMID: 24608022

Miller E, Carter S, Thomas S. Heart Disease in Pregnancy. In: Mieszczanska H and Velarde G, eds. Management of Cardiovascular Disease in Women. London: Springer; 2014:289-320. 

2013

Cameron SJ, Block R, Richeson JF.  Severe Coronary Disease in an Adult Considered at Low Cardiovascular Disease Risk with a Healthy Lifestyle.  J Clin Lipidol. 2013 Sep-Oct;7(5):526-30. PMID: 24079291

2012

Cameron SJ, Goulopoulo, S, Weil B, Kanaley, JA.  Regulation of arterial blood flow by aspirin following ischemia is a function of plasma HDL. Eur Rev Med Pharmacol Sci. 2012 Feb;16(2):143-50. PMID: 24382024