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About Us

The Immunohistochemistry (IHC) Laboratory provides clinical testing on surgical and cytology specimens for proteins, enzymes and infectious agents by immunohistochemical methods. We offer immunohistochemical and in-situ hybridization staining to outside clients with interpretation by our pathologists, or we return them for interpretation to the requesting pathologist.

Our unit provides the university community with extensive knowledge on immunohistochemical testing in both clinical and research settings. Most clinical testing is performed within 24 hours, giving rapid results to pathologists for final diagnosis. 

All of our stains are rigorously validated according to the latest CAP guidelines, providing test results which you can trust as the treatment plan is determined by the clinician and the patient; some examples include Estrogen and Progesterone Receptors, Her2-neu protein over-expression, and PD-L1 testing

What We Offer

Below are examples of the types of specimens on which we routinely perform IHC. You can also download our complete list of Immunohistochemical Stains

Contact Us

For questions, please contact the Immunohistochemistry Laboratory at (585) 275-7210. 

Specimen Description Image
Bone & Soft Tissue The epithelioid component of biphasic synovial sarcoma is highlighted by cytokeratin stain. Bone Pathology
Breast IHC confirms HER2 status in invasive breast cancer. Breast
Dermatological Cytokeratin 7 highlights the malignant cells in Paget disease. Paget disease
Gastrointestinal IgG4 immunostain highlights plasma cells in a case of autoimmune pancreatitis. Pancreatic Cancer
Genitourinary PIN4 multiplex stain confirms the presence of prostate cancer in small needle biopsies. Genitourinary stain
Gynecological Cervical rhabdomyosarcoma showing Myogenin expression. Gynecological Pathology
Thoracic (Lung) Squamous cell carcinoma demonstrating nuclear and cytoplasmic immunoreactivity with p16. Lung Pathology
Neurological Phosphotau immunoreactivity in neurofibrillary tangles, an IHC test for Alzheimer’s disease, variants of dementia and chronic traumatic encephalopathy. Neuropathology
Pediatric The immunostain p57 confirms the presence of a complete hydatiform mole. Pediatric Pathology