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Abe, Jun-ichi
Mechanism and significance of kinase and transcriptional factors in diabetes-related cardiovascular disease.
Berk, Bradford C.
Molecular biology and genetics of cardiovascular disease.
Bidlack, Jean M.
Pharmacology of brain and lymphocytic opioid receptors.
Blair, Martha L.
Neural and neuroendocrine control of cardiovascular function.
Blaxall, Burns C.
Cardiac gene expression and G-protein coupled receptor signaling.
Bowers, William J.
Dissecting the dynamic interplay between inflammation and Alzheimer's disease pathophysiology using novel transgenic modeling and immunotherapeutic approaches.
Brookes, Paul S.
Mitochondrial interactions with free radicals (nitric oxide, superoxide) in the context of myocardial ischemia reperfusion.
Chang, Chawnshang
Androgen receptor and AR coregulators in androgen-related diseases, such as prostate/breast/liver cancer.
Dickerson, Ian
Molecular mechanisms of neuropeptide signal transduction.
Dirksen, Robert T.
Calcium channel structure and function.
Freeman, Robert S.
Molecular mechanisms of neuronal death.
Fujiwara, Keigi
Molecular mechanism of mechano-signaling and response by endothelial cells, especially the role of cytoskeleton and intercellular adhesion molecules.
Glading, Angela J.
Regulation of cell-cell contact in health and disease.
Gross, Robert A.
Cellular mechanisms of opioid desensitization and tolerance; mechanisms underlying altered Ca homeostasis in excitotoxic injury; role of growth factors in regulating excitability in epilepsy models.
Haber, Suzanne N.
Integrative functions of the basal ganglia and its relationship to neurological and psychiatric disorders.
Hammes, Stephen R.
The Hammes laboratory studies ovarian development and function, focusing on how dysregulation of steroidogenesis and steroid signaling leads to diseases of androgen excess such as polycystic ovarian syndrome.
Hinkle, Patricia M.
Molecular mechanisms of cell regulation.
Hocking, Denise C.
Regulation of cell behavior by the extracellular matrix.
Ivanov, Andrei I.
Basic mechanism regulating the formation and functions of epithelial apical junctions as well as on mechanisms mediating disruption of epithelial cell-cell adhesions in inflammation and cancer.
Jin, Zheng-Gen
Molecular regulation of vascular endothelial function and vascular diseases.
Johnson, Gail V.W.
Mitochondrial dysfunction and the molecular mechanisms of neurodegeneration; the regulation and function of transglutaminase 2; tau pathology in Alzheimer's disease; the role of mitochondria in the pathogenesis of Huntington's disease.
Kammermeier, Paul J.
G protein coupled receptor signaling and modulation of ion channels in neurons.
Krieger, Nancy S.
Mechanisms of regulation of bone calcium metabolism, with an emphasis on signal transduction pathways involved in hormonal and acid-mediated effects on bone-cell function.
Lopes, Coeli M.B.
Molecular mechanisms of cardiac potassium channel regulation in health and disease.
Mayer-Proschel, Margot
Our central goal is to understand the biological and molecular mechanisms governing precursor cell division, differentiation, and survival in the brain.
Melvin, James E.
Exocrine gland physiology - water movement and ion transport.
Nehrke, Keith
Integrative physiology in the nematode C. elegans.
Noble, Mark
Stem cell biology, regeneration in the central nervous system, redox modulation of precursor cell function, developmental disorders, brain tumor biology and adverse effects of chemotherapy of neural stem cell populations.
O'Keefe, Regis J.
Growth plate chondrocyte differentiation and maturation; biochemical mechanisms of prosthetic implant loosening; mechanisms of tumor mediated bone loss.
Pentland, Alice P.
The role of phospholipases and cyclooxgenases in epidermal function
Plessinger, Mark
Plasticity and cellular functions of amniotic epithelial cells and fibroblasts: cytokine production and collagen regulation in human fetal membranes.
Porter, Jr., George A.
Regulation of cardiac development by intracellular calcium signaling and mitochondrial biogenesis.
Pryhuber, Gloria
Tumor necrosis factor alpha (TNF-a) signal transduction and subsequent gene regulation in pulmonary epithelium.
Puzas, Edward J.
Molecular and cellular biology of the skeletal system.
Rahman, Arshad
Signaling mechanisms of endothelial ICAM-1 expression and neutrophil-mediated lung vascular injury.
Rahman, Irfan
Oxidative stress, glutathione regulation, NF-kB, redox signaling and gene expression.
Rempe, David A.
The goal of our laboratory is to define the adaptive and pathological responses of the brain during hypoxia/ischemia that alter neuronal viability and function.
Rosier, Randy N.
Regulation of endochondral ossification.
Sarelius, Ingrid H.
Vascular cell communication and signaling.
Schaefer, Katherine L.
Regulation of the cytoskeleton in cancer.
Sheu, Shey-Shing
Mitochondrial calcium signaling in normal and diseased heart cells and neurons.
Simpson-Haidaris, Patricia J.
Role of fibrinogen in acute phase response in pneumonitis and fibrinogen gene expression in liver and lung.
Smrcka, Alan V.
Molecular mechanisms of signal transduction.
Sottile, Jane
Molecular mechanisms by which the extracellular matrix controls cell behavior.
Sun, Jun
Molecular mechanism of signal transduction in inflammation and cancer.
Sun, Yin
TGF-b regulation of proliferation and differentiation.
Tall, Gregory G.
Mechanisms of signal transduction, heterotrimeric G protein signaling.
Tank, A. William
Regulation of tyrosine hydroxylase gene expression.
Waugh, Richard E.
Regulation and molecular basis of the mechanical stability of cells, cell membranes, and cell adhesion
Welle, Stephen L.
Regulation of skeletal muscle growth and atrophy.
Yan, Chen
Regulation and function of cyclic nucleotide phosphodiesterases in the cardiovascular system.
Yoon, Yisang
Cell biology of mitochondria: Regulation of mitochondrial dynamics.
Young, Fay
Normal and abnormal B-lymphocyte development.
Yule, David I.
Mechanisms underlying Ca2+ signaling events in exocrine cells.
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