Faculty

 

Jun-ichi Abe

Jun-Ichi Abe, M.D., Ph.D.

Mechanism and significance of kinase and transcriptional factors in diabetes-related cardiovascular disease.

Bradford C. Berk, M.D., Ph.D.

Bradford C. Berk, M.D., Ph.D.

Molecular biology and genetics of cardiovascular disease.

Jean M. Bidlack, Ph.D.

Jean M. Bidlack, Ph.D.

Pharmacology of brain and lymphocytic opioid receptors.

Paul S. Brookes, Ph.D.

Paul S. Brookes, Ph.D.

Mitochondrial interactions with free radicals (nitric oxide, superoxide) in the context of myocardial ischemia reperfusion.

Ian Dickerson, Ph.D.

Ian Dickerson, Ph.D.

Molecular mechanisms of neuropeptide signal transduction.

Robert T. Dirksen, Ph.D.

Robert T. Dirksen, Ph.D.

Calcium channel structure and function.

Robert S. Freeman, Ph.D.

Robert S. Freeman, Ph.D.

Molecular mechanisms of neuronal death.

Keigi Fujiwara, Ph.D.

Keigi Fujiwara, Ph.D.

Molecular mechanism of mechano-signaling and response by endothelial cells, especially the role of cytoskeleton and intercellular adhesion molecules.

Angela J. Glading, Ph.D.

Angela J. Glading, Ph.D.

Regulation of cell-cell contact in health and disease.

Robert A. Gross, M.D., Ph.D.

Robert A. Gross, M.D., Ph.D.

Cellular mechanisms of opioid desensitization and tolerance; mechanisms underlying altered Ca homeostasis in excitotoxic injury; role of growth factors in regulating excitability in epilepsy models.

Haber

Suzanne N. Haber, Ph.D.

The basal ganglia and the rewards circuit.

Stephen R. Hammes, M.D., Ph.D.

Stephen R. Hammes, M.D., Ph.D.

The Hammes laboratory studies ovarian development and function, focusing on how dysregulation of steroidogenesis and steroid signaling leads to diseases of androgen excess such as polycystic ovarian syndrome.

Denise C. Hocking, Ph.D.

Denise C. Hocking, Ph.D.

Regulation of cell behavior by the extracellular matrix.

Zheng-Gen Jin, Ph.D.

Zheng-Gen Jin, Ph.D.

Molecular regulation of vascular endothelial function and vascular diseases.

Gail V.W. Johnson, Ph.D.

Gail V.W. Johnson, Ph.D.

Mitochondrial dysfunction and the molecular mechanisms of neurodegeneration; the regulation and function of transglutaminase 2; tau pathology in Alzheimer's disease; the role of mitochondria in the pathogenesis of Huntington's disease.

Paul J. Kammermeier, Ph.D.

Paul J. Kammermeier, Ph.D.

G protein coupled receptor signaling and modulation of ion channels in neurons.

 

Nancy S. Krieger, Ph.D.

Mechanisms of regulation of bone calcium metabolism, with an emphasis on signal transduction pathways involved in hormonal and acid-mediated effects on bone-cell function.

Coeli M.B. Lopes, Ph.D.

Coeli M.B. Lopes, Ph.D.

Molecular mechanisms of cardiac potassium channel regulation in health and disease.

Joseph M. Miano, Ph.D.

Joseph M. Miano, Ph.D.

Transcriptional regulation of gene expression; pathobiology of SRF and myocardin; genome mining.

Keith Nehrke, Ph.D.

Keith Nehrke, Ph.D.

Integrative physiology in the nematode C. elegans.

George A. Porter, Jr., M.D., Ph.D.

George A. Porter, Jr., M.D., Ph.D.

Regulation of cardiac development by intracellular calcium signaling and mitochondrial biogenesis.

Sarelius

Ingrid H. Sarelius, Ph.D.

Vascular cell communication and signaling.

Smrcka

Alan V. Smrcka, Ph.D.

Molecular mechanisms of signal transduction.

Jane Sottile, Ph.D.

Jane Sottile, Ph.D.

Molecular mechanisms by which the extracellular matrix controls cell behavior.

Gregory G. Tall, Ph.D.

Gregory G. Tall, Ph.D.

Mechanisms of signal transduction, heterotrimeric G protein signaling.

Tank

A. William Tank, Ph.D.

Regulation of tyrosine hydroxylase gene expression.

Richard E. Waugh, Ph.D.

Richard E. Waugh, Ph.D.

Regulation and molecular basis of the mechanical stability of cells, cell membranes, and cell adhesion.

Chen Yan, Ph.D.

Chen Yan, Ph.D.

Regulation and function of cyclic nucleotide phosphodiesterases in the cardiovascular system.

David I. Yule, Ph.D.

David I. Yule, Ph.D.

Mechanisms underlying Ca2+ signaling events in exocrine cells.

 

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