Dr. Linda Spear presents talk titled:"Contributors to and consequences of adolescent alcohol exposure: Studies in a rodent model"
Adolescents ingest more alcohol per occasion than do adults. This age effect is evident not only in human adolescents but also in laboratory animals undergoing this developmental transition, suggesting that such intakes may be partly biologically based. Work using rodent models has revealed that adolescents display an attenuated sensitivity to many alcohol effects likely serving as cues to moderate drinking, but enhanced sensitivity to ethanol-induced social stimulation and rewarding effects. This developmental blending of increased and decreased EtOH sensitivities may promote relatively high levels of alcohol intake, especially among at-risk adolescents, potentially leading to lasting adverse consequences. Indeed, recent pre-clinical studies have revealed notable enduring neural and behavioral consequences of adolescent EtOH exposure, including persistence of some adolescent phenotypes into adulthood.
|Location: ||Auditorium K-307 (3-6408)|
Posted by: Ania Dworzanski, Neurobiology & Anatomy, 17-Nov-15 4:00pm ET