Alumni

The Biology of 1-Methyladenosine and Initiator tRNA in Evolutionarily Distant Yeast Species, and Other Aspects of tRNA Modification Biology

Advisor: Eric Phizicky, Ph.D.

Now: Research Scientist in R & D at hC Bioscience

The Role of CRISPR-Csx28 in CRISPR-Cas Anti-Phage Immunity

Advisor: Mitchell O'Connell, Ph.D.

Now: Postdoctoral Associate at Molecular Biology Department, University of California-San Diego

Global Analysis of the Interplay Between Protein Folding Stabilities and Methionine Oxidation

Advisor: Sina Ghaemmaghami, Ph.D.

Now: Postdoctoral Associate at Broad Institute

New methods to improve the efficiency of RNA-targeted compounds: application to HIV

Advisor: Benjamin Miller, Ph.D.

Now: Postdoctoral researcher at Broad Institute of MIT and Harvard

Mechanisms of Translation Pausing Induced by mRNA Secondary Structures

Advisor: Dmitri Ermolenko, Ph.D.

Now: Research Investigator at Incyte

Identifying Molecular Determinants of the Structure of the Intrinsically Disordered H1.0 Carboxyl-Terminal Domain

Advisor: Jeffrey Hayes, Ph.D.

Now: Scientist at Vertex Pharmaceuticals

An Analysis of Factors Involved in Translation Frameshifting and Inhibition due to Inhibitory Codon Pairs in Saccharomyces cerevisiae

Advisor: Elizabeth Grayhack, Ph.D.

Now: Application Scientist at Agilent Technologies

Investigating the Roles for Histone H2A Variants in Late-Stage Erythropoietic Nuclear Condensation and Gene Regulation

Advisor: Michael Bulger, Ph.D.

Now: Scientist I/Manager at bluebird bio

Roles of Cyclic Nucleotide Phosphodiesterases in Smooth Muscle Cells and the Pathogenesis of Vascular Restenosis

Advisor: Xin Li, Ph.D. & Chen Yan, Ph.D.

Now: Postdoctoral scholar at Stanford Univ.

Probing genome-wide native chromatin structure via histone surface accessibilities

Advisor: Jeffrey Hayes, Ph.D.

Now: Associate Product Manager at Thermo Fisher Scientific

Similarities and differences in tRNA quality control decay pathways in evolutionarily distant yeast species

Advisor: Eric Phizicky, Ph.D.

Now: Postdoctoral Fellow at Harvard Univ.

The Mechanism and Function of RNA-Guided RNA Pseudouridylation

Advisor: Yi-Tao Yu, Ph.D.

Now: Scientist Molecular/Viral Vector Biology at ElevateBio

Investigating the Function of Hyperacetylated Chromatin Domain-Forming Enhancers

Advisor: Michael Bulger, Ph.D.

Now: Postdoctoral researcher at Coriell Institute for Medical Research

The intersection of Human Cytomegalovirus infection and innate immune signaling

Advisor: Joshua Munger, Ph.D.

Now: Medical Writer at ApotheCom: A MEDiSTRAVA Company

The role of the intrinsic closeness of mRNA ends in translation

Advisor: Dmitri Ermolenko, Ph.D.

Now: Senior Quality Engineer at Amgen

Reading frame maintenance at translation stalls in yeast involves eukaryotic specific mechanisms

Advisor: Elizabeth Grayhack, Ph.D.

Now: Data Science Analyst at Mayo Clinic

Use of Yeast Surface Display to Identify Variants of HIV Envelope Glycoprotein with Enhanced Affinity for Precursors to Broadly Neutralizing Antibodies

Advisor: Mark Dumont, Ph.D.

Now: Healthcare Strategy Consulting at Fletcher Spaght, Inc.

Molecular Characterization of Nucleosome Recognition by Linker Histone H1.0

Advisor: Jeffrey Hayes, Ph.D.

Now: Senior Test Engineer at Ginkgo BioWorks, Inc

The Biology of Anticodon Stem-Loop Modifications of Yeast tRNAs

Advisor: Eric Phizicky, Ph.D.

Now: Scientist, RNA Biology at Arrakis Therapeutics

ER-associated Functions of the Double-stranded RNA-binding Protein Staufen1

Advisor: Lynne Maquat, Ph.D.

Now: Senior Research Scientist at UMass Chan Medical School

Insights into G protein βγ Regulation of Phospholipase Cε

Advisor: Alan Smrcka, Ph.D.

Now: Editor at Trends in Pharm. Sciences at Cell Press

Characterization of tRNA Quality Control Pathways in Yeast

Advisor: Eric Phizicky, Ph.D.

Now: Postdoctoral Researcher at National Institute on Aging

KNa1.2 as a Cardiac Mitochondrial Potassium Channel with Metabolic Impact on Energy Usage

Advisor: Paul Brookes, Ph.D.

Now: Chief Scientific Officer at CannaMetrix

Specific Codon Pairs Inhibit Translation in Yeast and Act by Distinct Mechanisms

Advisor: Elizabeth Grayhack, Ph.D.

Now: Associate at Heslin Rothberg Farley & Mesiti P.C.

Regulation of Ribosome Structural Dynamics by Antibiotics, Translation Factors and mRNA Secondary Structure

Advisor: Dmitri Ermolenko, Ph.D.

Now: Scientific reviewer at FDA

Computational Tools for RNA Structure Prediction

Advisor: David Mathews, M.D., Ph.D.

Now: Data Scientist at Xometry

The Impact of Oncogenic Signaling on Metabolic Stress Responses and Human Cytomegalovirus Infection

Advisor: Joshua Munger, Ph.D.

Now: Senior Scientist at Merck

Characterization of ATP-Dependent Chromatin Remodeler-Nucleosome Interactions and Analysis of the Role of HMGB1 in Base Excision Repair

Advisor: Jeffrey Hayes, Ph.D.

Now: Senior Molecular Biologist II at Antylia Scientific

Investigating the Role of Prostaglandin E2 Receptor Subtype 1 in Mesenchymal Stem Cell Differentiation

Advisor: Jeffrey Hayes, Ph.D. & Regis O'Keefe, M.D., Ph.D.

Now: Senior Scientist at Axcella Health

Characterization of PIN-domain Toxin-antitoxins VapBC from Mycobacterium tuberculosis

Advisor: Scott Butler, Ph.D.

Now: Software Engineer at LenelS2

Contributions of Pyrimidine Biosynthesis to Viral Infection

Advisor: Joshua Munger, Ph.D.

Now: Assistant Professor at Department of Biological Sciences, University of Delaware

Identification of A2 Inter-Subunit Interactions in Factor VIIIa of the Blood Clotting Pathway

Advisor: Philip Fay, Ph.D.

Now: Clinical Trials Medical Writer at ACM Global Laboratories

The Non-Histone Protein HMGN1 Alters Core Histone Tail and H1 Interactions to Modify Higher-Order Chromatin Structure

Advisor: Jeffrey Hayes, Ph.D.

Now: Principal Scientist, Bioprocess Development at Zoetis Inc.

Stimulation of Neutrophil Migration through the Dynamic Regulation of Signaling by the Heterotrimeric G Proteins ai and bgSubunit

Advisor: Alan Smrcka, Ph.D.

Now: Scientific Researcher at Gilead Sciences

Beta-catenin signaling integrates with BMP2 and CCN1 signaling to regulate chondrocyte differentiation and cartilage development

Advisor: Regis O'Keefe, M.D., Ph.D.

Now: Associate Research Scientist at Columbia University

Hyperacetylated Domain Formation and cis-acting Regulatory DNA Sequences within the Murine β-globin Locus

Advisor: Michael Bulger, Ph.D.

Now: Research Associate at University of Puerto Rico

Characterizing the Role of Elongation Factor 1A and Other Cellular Proteins in the Yeast Rapid tRNA Decay Pathway

Advisor: Eric Phizicky, Ph.D.

Now: Principal Scientist at Nova Rock Biotherapeutics

Structural and Functional Analysis of Gene Regulatory PreQ1 Riboswitches

Advisor: Joseph Wedekind, Ph.D.

Now: Associate Director, Medical Affairs at uniQure

Characterization of the APOBEC3G ssDNA Editing Complex and its Regulation by RNA

Advisor: Harold Smith, Ph.D.

Now: Assistant Professor at University of Massachusetts

Tissue Specific Gene Activation by a Class of Enhancers in Hyperacetylated Domains of Chromatin

Advisor: Michael Bulger, Ph.D.

Now: Medical Writer at Pfizer

Investigation of an evolutionarily conserved Staufen-mediated mRNA decay pathway that involves SINEs and lncRNAs

Advisor: Lynne Maquat, Ph.D.

Selection, Identification, and Characterization of Codon Pairs that Inhibit Translation and the Development of the RNA-ID Method to Measure the Effects of Cis-Regulatory Elements

Advisor: Elizabeth Grayhack, Ph.D.

Now: Clinical Project Manager at Becton Dickinson

Thermodynamic Analysis and Characterization of Viral-Host Protein Interactions as a Preface to HIV Therapeutic Design

Advisor: Joseph Wedekind, Ph.D.

Now: Assistant Professor at Department of Biology, Alfred University

Characterization of Intra- and Inter-nucleosomal Interactions of the Histone H4 Tail Domain and the Effects of H4 Acetylation on Chromatin Structure

Advisor: Jeffrey Hayes, Ph.D.

Now: Educator at Cold Spring Harbor Laboratory, DNA Learning Center

Fatty Acid Biosynthesis: Elucidating the Mechanisms Behind the Manipulation and Necessity of a Metabolic Pathway Critical for Viral and Cancer Pathogenesis

Advisor: Joshua Munger, Ph.D.

Now: Senior Research Scientist at Bio X Cell

Identification of Mutations Affecting the Thermal Stability of Ste2p, a G Protein Coupled Receptor in S. cerevisiae

Advisor: Mark Dumont, Ph.D.

Now: Bioinformatics Scientist at Alnylam Pharmaceuticals

The Mechanisms for Catalytic Inactivation of FVIIIa by APC and Factor Xa

Advisor: Philip Fay, Ph.D.

Now: Photographer at Jennydee Photography

The Role of Glutamate Receptors in the Pathophysiology and Treatment of Infantile Neuronal Ceroid Lipofuscinosis

Advisor: David Pearce, Ph.D.

Now: Licensing Officer at Virginia Tech

Binding and Cleavage Specificities of Human Dna2 and FEN1 Define Their Enzymatic Activities during DNA Replication and Repair

Advisor: Robert Bambara, Ph.D.

Now: Director Business Relations & Portfolio Management at Excellus BCBS

Staufen1-Mediated mRNA Decay in Mammalian Cells

Advisor: Lynne Maquat, Ph.D.

Now: Investigator II at Novartis Institutes for Biomedical Research

Human Telomere DNA Damage by Oxidation and Direct Effect Ionizing Radiation, and the Promotion of Telomere DNA Repair by Telomere Proteins

Advisor: Robert Bambara, Ph.D.

Now: Senior QC Scientist at Regeneron Pharmaceuticals

Understanding the Molecular Mechanisms of Genome Maintenance

Advisor: Robert Bambara, Ph.D.

Now: Medical Director of Pathology Informatics at Bingham and Women’s Hospital

Air Proteins Control Differential TRAMP Substrate Specificity for Nuclear RNA Surveillance

Advisor: Scott Butler, Ph.D.

Now: Principal Scientist at Alnylam Pharmaceuticals

Factors that Promote Strand Transfer Recombination during HIV-1 Reverse Transcription

Advisor: Robert Bambara, Ph.D.

Now: Sr. Principal Scientist, Drug Safety R & D at Pfizer

Uncovering the Mechanism by Which Human Cytomegalovirus Mediates Glycolytic Activation

Advisor: Joshua Munger, Ph.D.

Now: Manager of QC & Technical Support at Zepto Metrix Corporation

Constitutive and inducible pseudouridylation of S. cerevisiae U2 snRNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Principal Statistical Analyst at Merck

Quality control and organization of small ribosomal subunit biogenesis

Advisor: Gloria Culver, Ph.D. & Eric Phizicky, Ph.D.

Now: Principal Scientist at Modalis Therapeutics

Studies in Oxidative Damage Induced Signaling: A Focus Outside the Nucleus

Advisor: Robert Bambara, Ph.D. & Michael O'Reilly, Ph.D.

Now: Assistant Professor at Department of Anesthesiology, University of Rochester

Multiple Roles for Members of the Long Flap Pathway in Okazaki Fragment Processing

Advisor: Robert Bambara, Ph.D.

Now: Assistant Professor at Department of Chemistry, Wilkes University, PA

Defying and Defeating Cancer: Hyaluronic Acid and the Rad51 Promoter

Advisor: Michael Bulger, Ph.D. & Vera Gorbunova, Ph.D.

Now: Assistant Staff at Learner Research Institute

Regulation of Translation Termination by Box H/ACA RNP-mediated Post-transcriptional Modification

Advisor: Yi-Tao Yu, Ph.D.

Now: Associate Professor at Vanderbilt University

Roles of Hho1p, Esc2p, and the post-translational modification of Sir2p in transcriptional silencing in Saccharomyces cerevisiae

Advisor: Jeffrey Hayes, Ph.D. & Xin Bi, Ph.D.

Now: Owner & Head Coach at Run with Holly

Mechanism of ySWI/SNF and RSC catalyzed nucleosome sliding

Advisor: Jeffrey Hayes, Ph.D.

Now: Assistant Laboratory Director, Clinical Biochemical Genetics at Baylor Genetics

Pseudouridylation of the Branch Site Recognition Region of U2 Affects Spliceosome Structure and Function

Advisor: Yi-Tao Yu, Ph.D.

Now: Chief Intellectual Property Officer at Steuben Foods

Conformational Changes Associated with Activation of the Yeast Saccharomyces cerevisiae α-factor Receptor Ste2p

Advisor: Mark Dumont, Ph.D.

Now: Postdoctoral Research at Univ. of Colorado Auschutz Medical Campus

Defining the Substrate Specificity Determinants for the Yeast Rapid tRNA Decay Pathway and the Identification of Factors that Mediate Degradation

Advisor: Eric Phizicky, Ph.D.

Now: Development Scientist I at New England Biolabs

Studies of the Cell Biology of CLN3 and Cell Motility Defects in the Cln3-/- Mouse

Advisor: David Pearce, Ph.D.

Now: Biology/Chemistry Teacher at The Taft School

Molecular Determinants of Linker Histone Binding to Nucleosomes

Advisor: Jeffrey Hayes, Ph.D.

Now: Global Clinical Program Leader at Proctor and Gamble

The Role of NPAT in S-Phase-Dependent Histone Gene Transcription and DNA Double-Strand Break Repair

Advisor: Jeffrey Hayes, Ph.D. & Jiyong Zhao, Ph.D.

Now: Scientific Consultant at Diamond Age Data Science

Development of a Bipartite Herpes Simplex Virus Sleeping Beauty Amplicon Vector Platform: Toward Site-Directed Integration of Large Transgenons Within the Human Genome

Advisor: William Bowers, Ph.D.

Now: Vice President of Product Development at Shattuck Labs Inc.

A novel role for tumor suppressor gene Birt-Hogg-Dubé (BHD) in regulating ribosomal RNA (rRNA) synthesis

Advisor: Jeffrey Hayes, Ph.D. & Willis Li, Ph.D.

Now: Advisor-Grants and Alumni Relations at Christian Medical College & Hospital

2'O-methylation of Yeast Telomerase in RNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Associate Director at Ultragenyx Pharmaceutical Inc.

Mitochondrial membrane fusion, pH homeostasis and ROS signaling in C. elegans

Advisor: Joshua Munger, Ph.D. & Keith Nehrke, Ph.D.

Now: Instructor at Department of Biology, Genesee Community College

Mechanisms and Functional Roles of Pseudouridines in RNAs

Advisor: Yi-Tao Yu, Ph.D.

Now: Physician Assistant at Baylor Scott & White Health

Understanding Why Three Pathways are Needed for Synthesis of Eukaryotic Nuclear DNA

Advisor: Robert Bambara, Ph.D.

Now: Health Plan Analytics Consultant at Excellus BCBS

Biophysical Characterization of the HIV-1 Viral Infectivity Factor and the Innate-Immunity Factor APOBEC3G

Advisor: Joseph Wedekind, Ph.D.

Now: Scientist at OyaGen Inc

The Formation and Function of Chromatin Domains at the Murine Beta Globin Locus

Advisor: Michael Bulger, Ph.D.

Now: Vice President of Research and Development at Shattuck Labs, Inc

Metabolic Regulation and Structural Evaluation of APOBEC-1 Complementation Factor

Advisor: Harold Smith, Ph.D.

Now: Associate at Department of Pathology and Laboratory Medicine, University of Rochester

The Production of Mitochondrial Reactive Oxygen Species at Steady-state Oxygen Concentrations: Implications for Oxygen Sensing

Advisor: Joshua Munger, Ph.D. & Paul Brookes, Ph.D.

Now: Scientist I - Molecular Screening at Cayman Chemical

Contributions of Active Site Docking and Exosite Binding to the Mechanism of Thrombin-Catalyzed Activation of Factor VIII

Advisor: Philip Fay, Ph.D.

Now: Instructor and Lab Coordinator at University of Maine

SYT-SSX1 Regulates PIASy Activity to Cause the Overexpression of NCOA3 in Synovial Sarcoma

Advisor: Yin Sun, Ph.D.

Now: Postdoctoral Research Scientist at German Cancer Research Center

Investigation of the Roles of the Highly Conserved G-1 Residue of tRNAHis and Analysis of Unexpected Modification Changes in tRNAHis Variants in Saccharomyces cerevisiae

Advisor: Eric Phizicky, Ph.D.

Now: Senior Applications Scientist at Promega Corporation

Mechanism Analysis of the Factors that Determine the Efficiency of Recombination Events during HIV-1 Reverse Transcription

Advisor: Robert Bambara, Ph.D.

Now: Category Manager at BASF Corporation

Studies on the Biochemical and Immunological Consequence of Lysosomal Dysfunction in Neuronal Ceroid Lipofuscinoses

Advisor: David Pearce, Ph.D.

Now: DNA Criminalist at Dept. of Criminal Investigation, State of Iowa

Identification of Novel Molecular Interactions of the Mitochondrial Fission Protein hFis1: Insight into its Action Mechanism and Therapeutic Potential

Advisor: Yisang Yoon, Ph.D.

Now: Assistant Professor at Icahn School of Medicine at Mount Sinai

Functional Interactions between Replication Protein A, Dna2, and Flap Endonuclease 1 during Okazaki Fragment Processing

Advisor: Robert Bambara, Ph.D.

Now: Assistant Professor, Department of Biology at University of South Carolina

Monocytes and Their Mitochondria in Alzheimer's Disease

Advisor: Thomas Gunter, Ph.D.

Now: Adjunct Curriculum Writer/Instructor at Rochester Institute of Technology

The Interrelationship between pH, Btn1p and Phospholipid Regulation

Advisor: David Pearce, Ph.D.

Now: Biology & Genetic Disease Scientist at Relay Therapeutics

Identification of Mitochondrial S-nitrosothiols and Determination of the Protective Effect of Mitochondrial S-nitrosation in Cardiac Ischemia Reperfusion Injury

Advisor: Paul Brookes, Ph.D.

Now: Associate Professor at Wells College

Core exosome independent function of the nuclear exoribonuclease Rrp6p

Advisor: Scott Butler, Ph.D.

Now: Associate Professor at St. John Fisher College

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22, and the 5’-3’ exonucleases Rat1 and Xrn1

Advisor: Eric Phizicky, Ph.D.

Now: Assistant Head of School at Namaste Montessori School

Activities of Two Base Excision Repair Enzymes on Nucleosomal Substrates

Advisor: Jeffrey Hayes, Ph.D.

Now: IRTA Fellow, Clark Lab at NIH

Factors That Promote Recombination during HIV-1 Reverse Transcription and Properties of M184 Drug Resistant Reverse Transcriptases

Advisor: Robert Bambara, Ph.D.

Now: Researcher at Univ. of Chicago

Unique Mechanisms that Control the Efficiency of HIV-1 Minus Strand Strong Stop Transfer

Advisor: Robert Bambara, Ph.D.

Now: Assistant director of Core Antisense Research at Ionis Pharmaceuticals

The Yeast Model for Batten Disease: Genetic and Physical Interactions

Advisor: David Pearce, Ph.D.

Now: Associate Professor, Department of Genetics, Molecular Biology, Cell Biology and Cell Signaling at Augustana University

Elucidating and Characterizing the Interacting Partners of the Neuronal Ceroid Lipofuscinoses Proteins

Advisor: David Pearce, Ph.D.

Now: Transformation Program Manager at Nouryon

A Functional Analysis of the Domains of APOBEC3G Involved in Dimerization, Anti-viral Activity and Cellular Localization

Advisor: Harold Smith, Ph.D.

Now: Chief Scientific Officer at Oyagen, Inc.

A Role for the Human Rad9-Rad1-Hus1 DNA Clamp Complex in DNA Repair

Advisor: Robert Bambara, Ph.D.

Now: Director of Career Development and Training at University of North Carolina at Chapel Hill

Analysis of the Mechanisms of 5-Fluorouracil Toxicity in Saccharomyces cerevisiae

Advisor: Scott Butler, Ph.D.

Now: Staff Scientist at National Cancer Institute

Identification of Yeast tRNASer Um44 2'-O-Methyltransferase (Trm44) and Demonstration of a Role of Trm44 in Maintaining Levels of Specific tRNASer Species

Advisor: Eric Phizicky, Ph.D.

Now: Postdoctoral Researcher at University of Minnesota-Twin Cities

Crystallographic Analysis of a Small Catalytic RNA and Structural Insights into the Enzymes and Substrates of RNA / DNA Editing

Advisor: Joseph Wedekind, Ph.D.

Now: Senior Pharmacokineticist at Covance

Distinguishing the Pathways of Primer Removal during Eukaryotic Okazaki Fragment Maturation

Advisor: Robert Bambara, Ph.D.

Now: Sr. Director, Corporate Communications & Investor Relations at ViaCyte

Contributions of Exosite Interactions and Active Site Docking to Activated Protein C-Catalyzed Inactivation of Factor VIIIa

Advisor: Philip Fay, Ph.D.

Now: Hematology Manager at Cerus

Studies of Signaling Pathways in Cellular Responses to Titanium Particles: Implications of Cyclooxgenes-2/Prostaglandin E2/RANK Ligand Induction in Fibroblasts During Wear Debris-Induced Osteolysis

Advisor: Regis O'Keefe, M.D., Ph.D.

Now: Associate Professor at Washington University School of Medicine at St. Louis

Functions and Mechanisms of RNA Pseudouridylation

Advisor: Yi-Tao Yu, Ph.D.

Now: Researcher at Umass Medical School

G Protein bg Subunit Mediated Signaling Specificity: Implications for bg subtypes and Novel Mechanisms of Activation

Advisor: Alan Smrcka, Ph.D.

Now: Director at Cowin Biosciences, Inc.

Probing Protein-Protein Interactions in Factor VIII: Characterization of Inter-Subunit Interactions and Epitope Mapping of Factor VIII Subunits

Advisor: Philip Fay, Ph.D.

Now: Program Director at NIH

dNTP Interaction Mechanisms of HIV-1 Reverse Transcriptase

Advisor: Baek Kim, Ph.D.

Now: Assistant Professor at SUNY Geneseo

Functional Dissection of Estrogen Signaling Pathways Conveyed by Estrogen Receptor Homodimers and Heterodimer

Advisor: Russell Hilf, Ph.D.

Now: CEO at Luxena Pharmaceuticals

The Human Papillomavirus E7 Oncoprotein Upregulates AKT Activity through the Retinoblastoma Protein (Rb) during Keratinocyte Differentiation

Advisor: Mark Dumont, Ph.D.

Now: CAR-T cell Scientist at Spring House

Essential Role of Proteoglycans in Caenorhabditis elegans Early Embryonic Cell Division and Characterization of Sequence Requirement for Proteoglycan Modification Site

Advisor: Fred Hagen, Ph.D.

Now: Analyst, Risk Business Intelligence at Kaiser Permanente

Ligand Binding and Receptor Activation in a G Protein Coupled Receptor in Baker’s Yeast Saccharomyces cerevisiae

Advisor: Mark Dumont, Ph.D.

Now: Technical Talent Sourcer at Microsoft

Identification of the Essential Yeast Gene THG1 Encoding the Unusual tRNAHis Degree Guanylytransferase, and Elucidation of Multiple Consequences of Thg1p Post Depletion in vivo

Advisor: Eric Phizicky, Ph.D.

Now: Assistant Professor, Cell Biology and Neuroscience at University of California Riverside

Protein Engineering and Rational Mutagenesis in the Crystallization and Structure Determination of Human Cyclin B1

Advisor: Ravi Basavappa, Ph.D.

Now: Assistant Professor at University of Novi Sad

Expression and Solubilization of Yeast Saccharomyces cerevisiae Integral Membrane Proteins for Functional and Structural Genomics

Advisor: Mark Dumont, Ph.D.

Now: Assistant Professor, Department of Genetics at Washington University in St. Louis

Structural and Functional Analysis of APOBEC-Related Editing Enzymes, and the Structural Basis of Antibody Specificity in Blood Type Recognition

Advisor: Joseph Wedekind, Ph.D.

Now: Lead Chemist at US Army Public Health Command - Region Pacific

Design of Estrogen Response Element (ERE) Binding Proteins to Study the Roles of ERE-containing Genes in Cell Proliferation and the Functional Differences Between ER Alpha and ER Beta

Advisor: Robert Bambara, Ph.D.

Now: Principal Investigator at The National Cancer Institute

Obesity-Associated Interleukin-6 Contributes to Hepatic Insulin Resistance in Mice

Advisor: Robert Mooney, Ph.D. & George Kimmich, Ph.D.

Now: Medical Writer II at Technical Resources International, Inc.

Degradation of mRNA in the nucleus and polyadenylation of noncoding RNA in Saccharomyces cerevisiae

Advisor: Fred Sherman, Ph.D.

Now: Senior Director at Head of DEL Biology WuXi AppTec

Identification of Pseudouridylases Responsible for the Formation of Pseudouridines in Yeast U2 snRNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Executive Director, Medical Affairs at Coherus BioSciences

The Transport and Metabolism of the Neurotransmitter Glutamate: Regulation of the Glutamate Transport EAAC1 by Protein Kinase C; and Aminotransferase- Catalyzed Isotope Exchange and its Implications for the Glutamate-Glutamine Shuttle Model

Advisor: George Kimmich, Ph.D.

Now: Chief Scientific Officer at SiMPore

The Mechanism of Minus Strand Stop Transfer during HIV-1 Reverse Transcription

Advisor: Robert Bambara, Ph.D.

Now: Scientific Officer at BioAgilytix

Cooperation of activated Ras and mutant p53 in control of cell motility and invasion during malignant cell transformation

Advisor: Hartmut Land, Ph.D.

Now: TBC at TBC

Intra- and Inter-nucleosomal Protein-DNA Interactions of the Core Histone Tail Domains in a Model Dinucleosome and Oligonucleosome Array

Advisor: Jeffrey Hayes, Ph.D.

Now: President and CEO at Robustnique Corporation

Investigation of the Mechanism of Nucleosome Remodeling by the Human SWI?SNF and Xenopus Mi-2 Chromatin Remodeling Complexes

Advisor: Jeffrey Hayes, Ph.D.

Now: Principal Editor for Benign Hematology at EBSCO Information Services

Investigation of Mitochondrial Protein Degradation Using Mutationally Altered Forms of Yeast Chromosome

Advisor: Robert Bambara, Ph.D. & Fred Sherman, Ph.D.

Now: Assistant Professor (tenure Track) at University of Pittsburg

Study on Roles of Eukaryotic Flap Endonuclease 1 (FEN1) in Maintaining Stability of Repeat Sequences During RNA Replication

Advisor: Robert Bambara, Ph.D.

Now: Associate Professor, Department of Chemistry & Biochemistry at Florida International University

Studying the Roles of Androgen Receptor (AR) Coactivators in Prostate Cancer Progression using Dominant-negative Mutants and RNA Interference

Advisor: Chawnshang Chang, Ph.D. & Fred Sherman, Ph.D.

Now: Scientist at Pfizer

The Mechanism of Recombination of HIV-1

Advisor: Robert Bambara, Ph.D.

Now: Assistant Professor of Neurology at John Hopkins Medicine

The molecular recognition of carbohydrates and ions in aqueous solution.

Advisor: Benjamin Miller, Ph.D.

Now: Associate Professor at Nazareth College

A Family of Dihydrouridine Synthases with Different Specificities Responsible for Modification of Cytoplasmic tRNAs of Saccharomyces cerevisiae

Advisor: Eric Phizicky, Ph.D.

Now: Research Fellow at Memorial Sloan Kettering Cancer Center

Analysis of Mammalian Base Excision Repair: Role of AP Endonuclease and Replication Protein A

Advisor: Robert Bambara, Ph.D.

Now: Senior Vice President at Quidel

Studies on Mechanisms of Estrogen Receptor Subtype-Specific Transcription Regulation

Advisor: Robert Bambara, Ph.D.

Now: Assistant Professor at Baylor College of Medicine

Intramolecular Interactions among Transmembrane Regions of STE2, a G Protein Coupled Receptor in Yeast Saccharomyces cerevisiae

Advisor: Mark Dumont, Ph.D.

Now: Director, Viral Vector Care at National Institute of Environmental Health and Sciences

Dominant Negative Mutations of the a-Factor Receptor Encoded by the STE2 Gene of the Yeast Saccharomyces cerevisiae

Advisor: Mark Dumont, Ph.D.

Now: TBC at TBC

Characterization of Estrogen-induced Synergistic Response at Multiple EstrogenResponsive Elements (EREs)

Advisor: Robert Bambara, Ph.D.

Now: US Regulatory Science Lead at UCB

Mechanisms of viral recombination by Human Immunodeficiency Virus Type I reverse transcriptase

Advisor: Robert Bambara, Ph.D.

Now: Medical Director at Cardiac Diagnostic Center, UC Irvine Medical Center

Biochemical mechanisms of DNA replication and repair and of HIV replication using mammalian enzymes

Advisor: Robert Bambara, Ph.D.

Now: Neurologist at Pathway Neurology