Students

Investigating differential intron sensitivity to core spliceosome factors that are amplified or deleted in developmental syndromes and cancer

Interplay Between Glutathione and Hepatic Lipid Metabolism

Tumor Necrosis Factor-alpha (TNFα) Induces Metabolic Reprogramming to Promote an Anti-viral Cell State

 Picking up the Pieces: The Fragmented Process of Cas13 Mediated RNA Cleavage in Human Cells

A UHM-ULM interface contributes to the pre-mRNA splicing functions of U2AF2 and SF3B1

Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 Mutations

Understanding the Role of RNA Structures in Regulating Upstream Open Reading Frames

Structural Characterization of a SIRT6-Nucleosome Array Complex

Modeling CDK12 and CDK13 loss-of-function (LOF) in prostate cancer cells to investigate their roles in alternative polyadenylation and neo-antigen expression

Identification and Structural Basis of a Novel Cellular Inhibitor of the Integrator Cleavage Module

Potential mRNA Translation-Related Function of RNA-Binding Protein PRRC2B

The Role of Histone Modifications and Variants in Longevity of Rodent Species

The Role of Enolase 2 During Human Cytomegalovirus Infection

The role of the Type VI CRISPR-Cas accessory protein Csx27 in the regulation of CRISPR-Cas13 mediated anti-viral immunity

Exploring the potential role of U2 m6Am modification in branch site recognition during pre-mRNA splicing

Identifying the Mechanisms of UL38-Mediated Metabolic Rigidity

A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

Defining the vulnerabilities of HCMV’s metabolic landscape 

Regulation of transcription by histone demethylase KDM5B in breast cancer

Inhibition of Precancerous Transformation via Drug-Induced p53 Activation

Targeting programmed ribosomal frameshifting in SARS-CoV-2 with a resin-bound dynamic combinatorial library

CRISPR-mediated Functional Dissection of the HCMV Interactome