Does this test have other names?
GGTP, gamma-glutamyl transferase, GGT
What is this test?
This test looks for an enzyme, or protein, called gamma-glutamyl transpeptidase (GGT)
in your blood.
GGT is found in liver cells. This test helps your doctor look for possible damage
to your liver or its ducts. It can also help tell the difference between liver and
bone disease if your results from a different blood test called alkaline phosphatase
Why do I need this test?
You may need this test if your healthcare provider suspects that you have liver damage.
One symptom of liver damage is jaundice, a yellowish tint to your skin and eyes. You
may also need this test to see if you have liver or bone disease. This test is also
used to look for chronic alcohol abuse.
What other tests might I have along with this test?
Your healthcare provider may also order other liver enzyme tests. These include:
Alanine aminotransferase, or ALT
Alkaline phosphatase, or ALP
Aspartate aminotransferase, or AST
Creatine phosphokinase, or CPK
Lactic dehydrogenase, or LDH
Leucine aminopeptidase, or LAP
What do my test results mean?
Many things may affect your lab test results. These include the method each lab uses
to do the test. Even if your test results are different from the normal value, you
may not have a problem. To learn what the results mean for you, talk with your healthcare
Results are given in international units per liter (U/L). Normal findings are:
Older adults may have slightly higher levels. Normal results for children are much
like those for adults. A newborn's level is 5 to 7 times higher than an adult's.
Higher than normal test results could be a sign of liver damage from diseases such
as hepatitis, cirrhosis, tumors, or pancreatic cancer. But a higher than normal GGT
level does not tell you the specific cause of liver disease or damage.
GGT is often higher a week or two after you've had a heart attack. It's unclear why
Higher GGT levels also may mean liver damage from heavy, chronic alcohol abuse. GGT
levels that are higher than normal may also signal a viral infection, such as Epstein-Barr.
How is this test done?
The test requires a blood sample, which is drawn through a needle from a vein in your
Does this test pose any risks?
Taking a blood sample with a needle carries risks that include bleeding, infection,
bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight
stinging sensation or pain. Afterward, the site may be slightly sore.
What might affect my test results?
Your test results might be affected if you are near the end of your pregnancy. Phenobarbital
and phenytoin can increase your GGT levels. Other medicines such as clofibrate and
birth control pills can lower your levels.
How do I get ready for this test?
You must not eat or drink anything but water for 8 hours before having this test.
Be sure your healthcare provider knows about all medicines, herbs, vitamins, and supplements
you are taking. This includes medicines that don't need a prescription and any illicit
drugs you may use.