Phosphatidylserine is a fat-soluble phospholipid. It occurs naturally in humans. It’s
the most abundant phospholipid in the human brain. It’s needed for many neuronal membrane
functions. Most of the body's phosphatidylserine comes of dietary sources.
Please note that this section reports on claims that have not yet been substantiated
Serine is a natural moisturizer. It’s included in many skin-care preparations.
Studies show that phosphatidylserine improves attention, arousal, verbal fluency,
and memory in seniors with cognitive issues. The mechanism of action is unclear. More
research is needed in this area.
Amino acids (AAs) are available as individual AAs or in AA combinations. They also
come as part of multi-vitamins, proteins, and food supplements. The forms include
tablets, fluids, and powders.
Note that by eating enough protein in your diet, you get all of the amino acids you
There are no conditions that increase how much serine you need.
Side effects, toxicity, and interactions
Using a single amino acid supplement may lead to negative nitrogen balance. This can
decrease how efficient your metabolism is. It can also make your kidneys work harder.
In children, taking single amino acid supplements may also cause growth problems.
You should not take high doses of individual amino acids for long periods of time.
Women who are pregnant or breastfeeding shouldn’t use serine supplements.