Our bodies, anthropologically, function solely to reproduce in order to preserve our species. But reproduction requires adequate metabolic energy. Witness the increase in body fat as one enters puberty or the negative effect on fertility for patients with anorexia nervosa, for those engaging in strenuous exercise, or those subjected to famine and starvation. Yet, as our ability to reproduce ceases at the other end of the age spectrum, we experience a reduction in metabolism, redistribution of fat to our abdominal area and, thus, the cardiovascular and diabetic risks of metabolic syndrome. The key to these interactions resides in our hypothalamus where reproduction and metabolism are controlled.