Developmental Impact of NICU Exposures (DINE)
Research Question:
Does exposure to phthalate in the neonatal intensive care unit harm cognitive development
of pre-term infants?
Basic Study Information
Purpose:
The DINE study will test the hypothesis that potentially avoidable NICU-based exposures
contribute to the neuro-cognitive and somatic impairments prevalent among NICU graduates.
This hypothesis is drawn from the documented impact of phthalate exposure on early
development in term-born children, and the acknowledged presence of these toxic chemicals
in
the NICU. Third trimester in utero exposure to phthalates have been linked to poorer
childhood performance in cognition, motor function, attention, hyperactivity and social
behavior. Phthalate exposure is also associated with altered onset of puberty and
asthma. The
multi-site cohort and approach will clarify the role of NICU-based phthalate exposure
on
high-prevalence clinical outcomes.
Location: University of Rochester
Lead Researcher (Principal Investigator)
Lead Researcher: Gloria Pryhuber
Study Contact Information
Study Coordinator: Gloria S Pryhuber, MD
Phone: (718) 839-7009
Email: judy.aschner@einstein.yu.edu
Additional Study Details
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