Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Patients With Chronic
How well is ibrutinib and obinutuzumab with or without venetoclax work in treating
patients with chronic lymphocytic leukemia?
Basic Study Information
Purpose:Location: University of Rochester Medical Center
This phase III trial studies how well ibrutinib and obinutuzumab with or without venetoclax
work in treating patients with chronic lymphocytic leukemia. Ibrutinib may stop the
growth of cancer cells by blocking some of the enzymes needed for cell growth. Immunotherapy
with monoclonal antibodies, such as obinutuzumab, may help the body's immune system
attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Drugs used in chemotherapy, such as venetoclax, work in different ways to stop the
growth of cancer cells, either by killing the cells, by stopping them from dividing,
or by stopping them from spreading. Giving ibrutinib, obinutuzumab and venetoclax
may work better in treating patients with chronic lymphocytic leukemia.
Study Reference #: CLYM19012
Lead Researcher (Principal Investigator)
Lead Researcher: Paul Barr
Study Contact InformationStudy Coordinator: Delaney Dretto
Phone: (585) 275-5825
Additional Study Details
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