A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults
With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen
Is a drug called, Olezarsen, safe in patients with familial chlyomicronemia syndrome
Basic Study Information
Purpose:Location: University of Rochester School of Medicine
Familial Chylomicronemia Syndrome (FCS) is a rare genetic disease that causes high
levels of fat in the blood. People with FCS have a high risk of developing pancreatitis,
a serious condition that can lead to death. There is no cure for FCS, but treatment
can help to manage the condition and reduce the risk of complications.
Olezarsen is a new drug that is being developed to treat FCS. It is a type of drug
that can block the production of a protein that helps to carry fat in the blood. By
blocking the production of this protein, Olezarsen can help to lower fat levels in
The purpose of the study is to determine if the drug is safe and tolerable in
participants with FCS previously treated with volanesorsen.
Participants will be eligible if they have FCS and are taking or have previously taken
the drug Volanesorsen.
Study Reference #: STUDY00007228
Lead Researcher (Principal Investigator)
Study Contact InformationStudy Coordinator: Ionis Pharmaceuticals
Phone: (844) 583-0450
Additional Study Details
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