Multi-Drug Resistant Gram Negative Bacilli (MUGSI) Surveillance
Multi-drug resistant gram-negative bacilli (MuGSI) are common causes of infections in both healthcare and community settings. Examples of gram-negative bacilli include E. coli and K. pneumoniae. These bacteria are increasingly becoming resistant to some antibiotics commonly used to treat them. To monitor trends in the incidence of MuGSI, we conduct population based surveillance among residents of Monroe County, NY.
Goals and Objectives
- Evaluate the population-based incidence of carbapenem-nonsusceptibility among common strains of Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter species and describe how the incidence changes over time
- Better characterize carbapenem-nonsusceptible strains in sites submitting data in order to inform prevention efforts
- Describe known resistance mechanisms among a subset of carbapenem-nonsusceptible Enterobacteriaceae
Working with laboratories in Monroe County, the surveillance team identifies carbapenem resistant organisms, as well as those resistant to third generation cephalosporins. Demographic data, as well as data about the nature of the identified bacterial culture are collected to identify potential risk factors for infection and to classify cases as Hospital-onset (HO), healthcare-associated community onset (HACO), or community-associated (CA). Selected isolates are sent to the Centers for Disease Control and Prevention (CDC) for further study.
Classification of MuGSI* cases - Monroe County, 2013-2016
*includes carbapenem-resistant E. coli, Klebsiella pneumoniae, Klebsiella oxytoca), Enterobacter aerogenes, E. cloacae complex, Acinetobacter baumannii, A. baumannii complex, and A. calcoaceticus-baumannii complex.
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- Guh, A: Bulens., SN; Mu, Y; Jacob, JT; Reno, J; Scott, J; Wilson, LE, Sc,M; Vaeth, E; Lynfield, R; Shaw, KM; Snippes, PM; Vagnone, MT(ASCP); Bamberg, WM; Janelle, SJ; Dumyati, G; Concannon, C; Beldavs, Z; Cunningham, M; Cassidy, M; Phipps, EC; Kenslow, N; Travis, T; Lonsway, D; Rasheed, JK; Limbago, BM; Kallen, AJ. Epidemiology of Carbapenem-Resistant Enterobacteriaceae in 7 US Communities, 2012-2013. Journal of the American Medical Association. 5 October 2015. Article Link
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