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Abdellatif Benraiss, Ph.D.Abdellatif Benraiss, Ph.D.
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Neurology
Goldman Lab

The use of gene therapeutic strategies to induce and regulate neurogenesis from endogenous neural stem cells in the adult mammalian brain, with a particular emphasis on developing this as a therapeutic strategy in Huntington's disease.
Devin Chandler-Militello, M.S.Devin Chandler-Militello, M.S.
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Neurology
Goldman Lab

Differentiation of human glial progenitor cells from iPSCs for amyotrophic lateral sclerosis to examine changes in gene expression. Working with Dr. Windrem to generate iPSC and hESC-derived glial progenitor cells for cell therapy.
Ting Du, M.D., Ph.D.Ting Du, M.D., Ph.D.
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Neurosurgery
Nedergaard Lab

Pathophysiological mechanisms of brain edema
Ali Erturk, Ph.D.Ali Erturk, Ph.D.
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Neurosurgery
Nedergaard Lab

Study of neurodegeneration and inflammation in acute brain injuries using tissue clearing technologies.
Steven Goldman, M.D., Ph.D.Steven A. Goldman, M.D., Ph.D.
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Neurology
Goldman Lab

Identify the expression patterns of the major categories of stem and progenitor cells of the adult human brain and to use that information to define the signaling pathways that distinguish one progenitor from another, as well as those that distinguish brain tumor stem and progenitor cells from their normal counterparts.
Rashad Hussain, Ph.D.Rashad Hussain, Ph.D.
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Neurosurgery
Nedergaard Lab

Glymphatic system in health and disease; neuron-glia interactions and signaling mechanisms.
Cui Li, Ph.D.Cui Li, Ph.D.
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Neurosurgery
Goldman Lab

JC virus-induced progressive multifocal leukoencephalopathy and HIV-associated neurocognitive disorder. Research is aimed at defining the course of disease development which will lead to new therapeutic strategies and early diagnosis.
Nanhong Lou, M.D.Nanhong Lou, M.D.
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Neurosurgery
Nedergaard Lab

The role of gliosis and glial cell signaling in stroke by using in vivo multiphoton imaging and electrophysiological methods.
Yuan Lu, Ph.D.Yuan Lu, Ph.D.
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Neurosurgery
Nedergaard Lab

Electrophysiological study of neuro-glia interaction in neurological diseases including Alzheimer's disease
Iben Lundgaard, Ph.D.Iben Lundgaard, Ph.D.
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Neurosurgery
Nedergaard Lab

The function of astrocyte-oligodendrocyte gap junctions.
Tamara Major, Ph.D.Tamara Major, Ph.D.
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Neurology
Goldman Lab

Application of glial progenitor cells derived from human embryonic stem (hES) cells and induced pluripotent stem (iPS) cells for neurodegenerative disease modeling and development of stem cell based therapeutic strategies.
Rupal Mehta, M.D.Rupal Mehta, M.D.
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Pathology & Laboratory Medicine
Nedergaard Lab
Mehta Lab

Small vessel disease and blood-brain barrier disruption in stroke
Maiken Nedergaard, M.D., DMScMaiken Nedergaard, M.D., DMSc
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Neurosurgery
Nedergaard Lab

The basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction.
Joana Osorio, M.D.Joana Osorio, M.D.
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Neurology
Goldman Lab

Cell based therapies for treatment of congenital disorders of myelin, particularly Pelizaeus Merzbacher disease and Krabbe disease. Gene editing of human induced pluripotent stem cells from patients with Pelizaeus Merzbacher disease for autologous cell transplantation. Differential characteristics of human and murine NG2+ oligodendrocyte progenitor cells in the grey and white matter. Migration and dispersal of human oligodendrocyte progenitor cells in the rat brain.
Weiguo Peng, M.D.Weiguo Peng, M.D.
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Neurosurgery
Nedergaard Lab

Spinal cord and spinal nerve injury; more specifically the secondary injury after spinal cord trauma and how to improve the recovery of spinal cord injury.
Jiandi Wan, Ph.D.Jiandi Wan, Ph.D.
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Imaging Sciences
Nedergaard Lab

Red cell mechanosensing dynamics, tissue engineering and fluid dynamics.
Martha Windrem, Ph.D.Martha Windrem, Ph.D.
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Neurology
Goldman Lab

The use of glial progenitor cells for treating disorders of myelin, in both pediatric and adult animal models of myelin disease. She also studies the biology of human astrocytes and oligodendrocytes in vivo, in chimeric brain models that permit the assessment of human cells in vivo, in rodent models of neurological disease.
Jim Xu, Ph.D.Jim Xu, Ph.D.
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Neurology
Nedergaard Lab

Using in vivo and in vitro electrophysiological, multiphoton, oxygen sensor and potassium sensor methods to investigate the physiological functions of astrocytes in the central nervous system.