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Research

The Department of Otolaryngology is devoted to the acquisition of new knowledge.

Your Otolaryngology residency at the University of Rochester will include research experiences intended to foster a culture of inquiry and instill curiosity about how you can leverage research to benefit your patients.

Throughout your residency, working with Otolaryngology faculty and our intramural collaborators, you will have clinical research opportunities ranging from case reports to clinical trials, and access to laboratory basic science and translational research projects. A research curriculum will guide you through planning, execution, analysis and presentation of a major research project that you will conduct during dedicated research time in PGY3.

Monthly departmental Research Conferences and the annual Department-sponsored Research Forum provide a stage for you to hone your presentation skills in preparation for attending and presenting your research at national meetings.

The Otolaryngology research program at the University of Rochester complements your mastery of surgical procedures and provides you with the tools to successfully participate in research throughout your career.

Otolaryngology Resident Research

Recent Research Topics (2013-2017)

Basic Science

Crane Lab

Research aimed at better understanding human motion perception and spatial orientation using psychophysical and engineering techniques to study head motion and its interaction with visual stimuli. https://www.urmc.rochester.edu/labs/crane.aspx

  • Bayesian Integration of Visual and Inertial Stimuli for Heading Perception
  • Illusory Motion and Heading Perception

Gill Lab

Research centered around microbial pathogens and the impact of human microbial flora on human health and disease. https://www.urmc.rochester.edu/labs/gill.aspx

  • Genome Integration and Quantitative Analysis of High-Risk HPV in Dysplastic Oral Cavity Lesions
  • Analysis of Sinus Sampling Techniques by 16S Sequencing
  • High Risk Human Papillomavirus in Tonsil Tissue: Prevalence in Healthy Adults and Co-localization within Crypt Biofilm
  • The Tumor Niche: The Interaction of Bacteria, the Immune System, and Tumor Cells in Oral Squamous Cell Carcinoma
  • Omics and Head & Neck Cancer: Fishing or Catching?

Benoit Lab

Research at the interface of medicine and engineering, with an emphasis on precisely controlling biomaterial functionality and architecture to treat diseases, control cell behavior, or answer fundamental biological questions. https://www.urmc.rochester.edu/labs/benoit.aspx

  • Effects of Sustained Release VEGF Mimetic Peptide Tissue Engineered Periosteum on Allograft Healing in a Murine Model
  • Tissue Engineering Approach to Mandibular and Midface Bone Regeneration
  • Osseous Reconstruction via 3D Printed Scaffolds and Tissue Engineered Periosteum
  • Craniofacial Defect Reconstruction via 3D Printed Scaffolds and Tissue Engineered Periosteum

Ovitt Lab

Research focused on two complementary approaches, one curative and one preventive - Regenerative strategies to restore salivary gland function in head and neck cancer survivors; and Improved protection strategies to prevent xerostomia in newly diagnosed patients https://www.urmc.rochester.edu/labs/ovitt.aspx

  • Salivary Gland Radioprotection by Localized Delivery of Amifostine in a Mouse Model

Holt Lab

Addressing the function of the vestibular efferent system from four vantage points: Identifying the receptor mechanisms by which different efferent responses are generated during activation of their pathways; Characterizing how these efferent receptor mechanisms modulate afferent response properties by pairing afferent recordings during vestibular stimulation with activation of efferent pathways; Identification of efferent discharge patterns with direct, in vivo recordings from vestibular efferent neurons. Development of behavioral assays for monitoring and evaluating vestibular efferent function in alert animal models. https://www.urmc.rochester.edu/labs/holt.aspx

  • Efferent and afferent Synaptic Mechanisms in the Murine Vestibular System: 2014 Update

Clinical Research

Clinical Trials

  • Oral vs. Topical Antibiotic Therapy for Treatment of Chronic Rhinosinusitis Exacerbations

Prospective Observational Studies

  • Voice and Swallow Outcomes in Head & Neck Cancer Patients Treated with Primary Chemo-Radiation: Correlation with Radiation Therapy Dosimetry on Anatomic Subunits
  • How Much Does it Really Hurt? Post-Tonsillectomy Pain Control: A Prospective Study
  • Congenital Cytomegalovirus (cCMV) Testing in Neonatal Patients Who Undergo Universal Newborn Hearing Screen (UNHS)
  • Defining Tip-Frenulum Length and Its Impact on Breastfeeding
  • In Vitro Efficacy of Consumer-Marketed Cerumen Removal Tool

Retrospective/Chart Reviews

Otology
  • Hearing Loss in a Refugee Population: A Case Series of Nepalese Presentation at a Local Health Center
  • Intraoperative Imaging of Cochlear Implantation
  • Transcanal Atticotomy for Challenging Cholesteatoma Surgery: Outcomes and Descriptions of a New Technique
  • Difference in Perioperative Outcomes in Local versus General Anesthesia in Stapedectomy
Pediatric ENT
  • The Effects of Timing of Pressure Equalization Tube Placement on Speech Thresholds
  • National Trends in Airway Management for Pierre-Robin Sequence
  • Long-Term Hearing Outcomes and Costs in the NICU Population
  • Effects of NY State Hearing Screening Demonstration Project: An Update
  • Morphine Solution for a Codeine Problem
  • Risk Factors Predictive of Need for Airway Intervention in Children after Tonsillectomy
  • Comparison on REM-only and NREM-only OSAS in Children: Polysomnographic and Clinical Characteristics
Head and Neck
  • Management Strategies of Synchronous Thyroid Cancer in the Setting of Head & Neck Malignancy: A Case Series
  • Incidence of Synchronous Thyroid Cancer in the Setting of Head and Neck Malignancy: A Case Series
  • Predictive Value of PET/CT in Detecting Cervical Metastasis in No Squamous Cell Carcinoma of the Head & Neck
  • State of Free-Flap Monitoring in the U.S.
  • Perioperative Glucose Control: A Retrospective Analysis of Perioperative Glucose Levels and Free Flap Complications
  • Age and the Betheda Thyroid Classification System
Rhinology
  • Post-Operative Outcomes of Middle Turbinate Medialization Endoscopic Endonasal Transphenoidal Surgery
  • Sinusitis after Endoscopic Transsphenoidal Pituitary Surgery: Is Pre-operative Imaging Predictive of Post-operative Sinonasal Disease?
Laryngology
  • Assessing Motivation to Change in Patients with Voice Disorders
  • Utility of Flexible Laryngoscopy in Patients with Globus Pharyngeus

Otolaryngology Faculty Research