HIV/AIDS and Skin Conditions
Skin conditions are common in people with HIV/AIDS. Many, such as molluscum contagiosum,
are caused by germs that take advantage of a weakened immune system. These may be
called opportunistic infections. Others, such as prurigo nodularis, may be linked
to inflammation caused by an immune system that works poorly.
Here are some of the more common skin conditions related to HIV/AIDS.
Molluscum contagiosum
This is a highly contagious viral skin infection. It may be passed from person to
person through skin-to-skin contact, by sharing linens, or by simply touching the
same objects. Molluscum contagiosum causes pink or flesh-colored bumps anywhere on
the skin. In people with HIV/AIDS, an outbreak can be mild. Or a person can have 100
or more bumps.
The bumps are often harmless. But they won't go away without treatment if your HIV
has worsened to AIDS. Antiretroviral therapy raises your CD4 lymphocyte count (also
called T cell count). This may help to improve the lesions. Your healthcare provider
may also recommend freezing off the bumps with liquid nitrogen (cryosurgery) or destroying
them with a laser or topical ointment. The treatment will often need to be repeated
until they're gone. They often return and need to be treated again.
Herpes viruses
Several types of herpes viruses are common in people with AIDS. Herpes simplex virus
infections cause an outbreak of sores around the genital area, the anus, or the mouth.
The varicella-zoster virus causes chickenpox. It can come out later in life as shingles. This
is sometimes a very painful, blistering rash on one side of the body.
Herpes infections are often treated with antiviral medicines. Nearly all herpes viruses
can become "latent." This means that the virus stays in the body even after the infection
seems to clear. It can come back and cause bouts of infection later on.
Kaposi sarcoma
This is a type of cancer. It starts in the cells that line the lymph or blood vessels.
Kaposi sarcoma causes dark lesions on the skin. These may appear as brown, purple,
or red patches or nodules. Kaposi sarcoma may also cause the skin to swell. The lesions
can affect organs, too, such as the lungs, liver, and parts of the digestive tract. They
can cause potentially life-threatening symptoms and breathing problems.
This skin condition often only happens when your T cell count is very low. This means
that your immune system is severely weakened. This condition is characteristic of
AIDS. When someone with HIV gets Kaposi sarcoma or any other opportunistic infection,
they are diagnosed with AIDS. Antiretroviral medicines to treat HIV/AIDS have greatly
reduced the incidence of Kaposi sarcoma. They also can help treat Kaposi sarcoma if
it develops. This cancer often responds to radiation, surgery, and chemotherapy.
Oral hairy leukoplakia
This is a viral infection that affects the mouth. It can cause thick, white lesions
on the tongue that sometimes look hairy. It is more common in people with AIDS who
have a very weak immune system. Oral hairy leukoplakia doesn't need specific treatment.
But taking antiretroviral medicines can improve your immune system and help to clear
up the infection.
Thrush
Oral candidiasis is also known as thrush. It is a fungal infection that causes a thick,
white or red layer to form on the tongue or inner cheeks. Thrush can be managed with
antifungal medicines, mouth lozenges, and mouth rinses. It is quite common in people
with HIV/AIDS. It can usually be treated. The infection tends to come back. Taking
effective HIV medicine often improves this condition and prevents it coming back.
Prurigo nodularis
This skin condition involves outbreaks of itchy, crusted lumps on the skin. The itching
can be intense and severe. Prurigo nodularis is most common in people with very weak
immune systems and among people of color with HIV/AIDS. Topical steroid treatment
(lotions or creams put right on the skin) and antiretroviral medicines are used to
treat the condition.
Antiretroviral medicines can help prevent and manage most of these types of skin conditions.
Other skin conditions may be triggered by the treatment and require other treatments.
Talk with your healthcare provider about the best therapy for your specific skin condition.