URMC / Labs / Mosmann Lab / Publications Publications Pichichero MECasey JRAlmudevar ABasha SSurendran NKaur RMorris MLivingstone AMMosmann TR (2016 Jun 15). Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants. The Journal of infectious diseases. Rebhahn JARoumanes DRQi YKhan AThakar JRosenberg ALee FEQuataert SASharma GMosmann TR (2016 Jan). Competitive SWIFT cluster templates enhance detection of aging changes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Aghaeepour NChattopadhyay PChikina MDhaene TVan Gassen SKursa MLambrecht BNMalek MMcLachlan GJQian YQiu PSaeys YStanton RTong DVens CWalkowiak SWang KFinak GGottardo RMosmann TNolan GPScheuermann RHBrinkman RR (2016 Jan). A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2016 Jan). Automated analysis of flow cytometry data comes of age. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Finak GLangweiler MJaimes MMalek MTaghiyar JKorin YRaddassi KDevine LObermoser GPekalski MLPontikos NDiaz AHeck SVillanova FTerrazzini NKern FQian YStanton RWang KBrandes ARamey JAghaeepour NMosmann TScheuermann RHReed EPalucka KPascual VBlomberg BBNestle FNussenblatt RBBrinkman RRGottardo RMaecker HMcCoy JP (2016). Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium. Scientific reports. Deng NMosmann TR (2015 Aug). Optimization of the cytokine secretion assay for human IL-2 in single and combination assays. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2015 Jul). State-of-the-Art in the Computational Analysis of Cytometry Data. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Kvistborg PGouttefangeas CAghaeepour NCazaly AChattopadhyay PKChan CEckl JFinak GHadrup SRMaecker HTMaurer DMosmann TQiu PScheuermann RHWelters MJFerrari GBrinkman RRBritten CM (2015 Apr 21). Thinking outside the gate: single-cell assessments in multiple dimensions. Immunity. Bobo BPhelan DRebhahn JPiepenbrink MSZheng BMosmann TRKobie JJDeLouise LA (2014 Sep 21). Microbubble array diffusion assay for the detection of cell secreted factors. Lab on a chip. Rebhahn JADeng NSharma GLivingstone AMHuang SMosmann TR (2014 Aug). An animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cells. European journal of immunology. Mosmann TRNaim IRebhahn JDatta SCavenaugh JSWeaver JMSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 2: biological evaluation. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Naim IDatta SRebhahn JCavenaugh JSMosmann TRSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 1: algorithm design. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Miao HSangster MYLivingstone AMHilchey SPZhang LTopham DJMosmann TRHolden-Wiltse JPerelson ASWu HZand MS (2014). Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection. PloS one. Deng NWeaver JMMosmann TR (2014). Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells. PloS one. Sharma SKRoumanes DAlmudevar AMosmann TRPichichero ME (2013 Jun 26). CD4+ T-cell responses among adults and young children in response to Streptococcus pneumoniae and Haemophilus influenzae vaccine candidate protein antigens. Vaccine. Aghaeepour NFinak G Hoos HMosmann TRBrinkman RGottardo RScheuermann RH (2013 Mar). Critical assessment of automated flow cytometry data analysis techniques. Nature methods. Weaver JMYang HRoumanes DLee FEWu HTreanor JJMosmann TR (2013). Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza. PloS one. Moore KWVieira PFiorentino DFTrounstine MLKhan TAMosmann TR (2012 Sep 1). Pillars article: homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science. 1990. 248: 1230-1234. Journal of immunology (Baltimore, Md. : 1950). Li XMiao HHenn ATopham DJWu HZand MSMosmann TR (2012 Jun 29). Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. Qi YOperario DJGeoras SNMosmann TR (2012). The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin. PloS one. Wu HKumar AMiao HHolden-Wiltse JMosmann TRLivingstone AMBelz GTPerelson ASZand MSTopham DJ (2011 Nov 1). Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors. Journal of immunology (Baltimore, Md. : 1950). Mace CRTopham DJMosmann TRQuataert SATreanor JJMiller BL (2011 Jan 15). Label-free, arrayed sensing of immune response to influenza antigens. Talanta. Qi YOperario DJOberholzer CMKobie JJLooney RJGeoras SNMosmann TR (2010 Dec). Human basophils express amphiregulin in response to T cell-derived IL-3. The Journal of allergy and clinical immunology. Miao HHollenbaugh JAZand MSHolden-Wiltse JMosmann TRPerelson ASWu HTopham DJ (2010 Jul). Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus. Journal of virology. Qian YWei CEun-Hyung Lee FCampbell JHalliley JLee JACai JKong YMSadat EThomson EDunn PSeegmiller ACKarandikar NJTipton CMMosmann TSanz IScheuermann RH (2010). Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data. Cytometry. Part B, Clinical cytometry. Mosmann TRKobie JJLee FEQuataert SA (2009 Dec). T helper cytokine patterns: defined subsets, random expression, and external modulation. Immunologic research. Hilchey SPKobie JJCochran MRSecor-Socha SWang JCHyrien OBurack WRMosmann TRQuataert SABernstein SH (2009 Nov 15). Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness. Journal of immunology (Baltimore, Md. : 1950). Lee HYHawkins EZand MSMosmann TWu HHodgkin PDPerelson AS (2009 Oct). Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models. Bulletin of mathematical biology. Henn ADRebhahn JBrown MAMurphy AJCoca MNHyrien OPellegrin TMosmann TZand MS (2009 Sep 1). Modulation of single-cell IgG secretion frequency and rates in human memory B cells by CpG DNA, CD40L, IL-21, and cell division. Journal of immunology (Baltimore, Md. : 1950). Friedberg JWKelly JLNeuberg DPeterson DRKutok JLSalloum RBrenn TFisher DCRonan EDalton VRich LMarquis DSims PRothberg PGLiesveld JFisher RICoffman RMosmann TFreedman AS (2009 Aug). Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. British journal of haematology. Lee HYTopham DJPark SYHollenbaugh JTreanor JMosmann TRJin XWard BMMiao HHolden-Wiltse JPerelson ASZand MWu H (2009 Jul). Simulation and prediction of the adaptive immune response to influenza A virus infection. Journal of virology. Hilchey SPHyrien OMosmann TRLivingstone AMFriedberg JWYoung FFisher RIKelleher RJBankert RBBernstein SH (2009 Apr 16). Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab. Blood. Seavey MMMosmann TR (2009 Apr 14). Estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming in response to intravaginal immunization. Vaccine. Wang JCKobie JJZhang LCochran MMosmann TRRitchlin CTQuataert SA (2009 Feb 28). An 11-color flow cytometric assay for identifying, phenotyping, and assessing endocytic ability of peripheral blood dendritic cell subsets in a single platform. Journal of immunological methods. Rebhahn JABishop CDivekar AAJiminez-Garcia KKobie JJLee FEMaupin GMSnyder-Cappione JEZaiss DMMosmann TR (2008 Oct). Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion. Computer methods and programs in biomedicine. Zaiss DMSijts AJMosmann TR (2008 Oct). Enumeration of cytotoxic CD8 T cells ex vivo during the response to Listeria monocytogenes infection. Infection and immunity. Seavey MMMosmann TR (2008). Immunoregulation of fetal and anti-paternal immune responses. Immunologic research. Lee FEWalsh EEFalsey ARLumb MEOkam NVLiu NDivekar AAHall CBMosmann TR (2007 Jun 15). Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection. The Journal of infectious diseases. Richter MRay SJChapman TJAustin SJRebhahn JMosmann TRGardner HKotelianski VdeFougerolles ARTopham DJ (2007 Apr 1). Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection. Journal of immunology (Baltimore, Md. : 1950). Zaiss DMYang LShah PRKobie JJUrban JFMosmann TR (2006 Dec 15). Amphiregulin, a TH2 cytokine enhancing resistance to nematodes. Science (New York, N.Y.). Seavey MMMosmann TR (2006 Dec 1). Paternal antigen-bearing cells transferred during insemination do not stimulate anti-paternal CD8+ T cells: role of estradiol in locally inhibiting CD8+ T cell responses. Journal of immunology (Baltimore, Md. : 1950). Kobie JJShah PRYang LRebhahn JAFowell DJMosmann TR (2006 Nov 15). T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. Journal of immunology (Baltimore, Md. : 1950). Snyder-Cappione JEDivekar AAMaupin GMJin XDemeter LMMosmann TR (2006 Feb 15). HIV-specific cytotoxic cell frequencies measured directly ex vivo by the Lysispot assay can be higher or lower than the frequencies of IFN-gamma-secreting cells: anti-HIV cytotoxicity is not generally impaired relative to other chronic virus responses. Journal of immunology (Baltimore, Md. : 1950). Divekar AAZaiss DMLee FELiu DTopham DJSijts AJMosmann TR (2006 Feb 1). Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. Journal of immunology (Baltimore, Md. : 1950). Yang LKobie JJMosmann TR (2005 Nov 15). CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells. Journal of immunology (Baltimore, Md. : 1950). Lee FEWalsh EEFalsey ARLiu NLiu DDivekar ASnyder-Cappione JEMosmann TR (2005 Nov). The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects. Mechanisms of ageing and development. Mosmann TRCherwinski HBond MWGiedlin MACoffman RL (2005 Jul 1). Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986. Journal of immunology (Baltimore, Md. : 1950). Ma JMosmann TWu H (2005). Design considerations for a web-based database system of ELISpot assay in immunological research. AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. Mosmann TRLivingstone AM (2004 Jun). Dendritic cells: the immune information management experts. Nature immunology. Yang LMosmann T (2004 Jun). Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions. European journal of immunology. Snyder JEMosmann TR (2003 May). How to "spot" a real killer. Trends in immunology. Snyder JEBowers WJLivingstone AMLee FEFederoff HJMosmann TR (2003 Feb). Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing. Nature medicine. Wang XMosmann T (2001 Oct 15). In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells. The Journal of experimental medicine. Mosmann T (2001 May). Measurement of mouse and human interleukin 10. Current protocols in immunology / edited by John E. Coligan ... [et al.]. Mosmann T (2000 Dec). Complexity or coherence? Cytokine secretion by B cells. Nature immunology. Mosmann T (2000 Apr). Reply to cohen Immunology today. Li LXia YNguyen ALai YHFeng LMosmann TRLo D (1999 Mar 1). Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. Journal of immunology (Baltimore, Md. : 1950). Lai YHMosmann TR (1999 Jan 1). Mouse IL-13 enhances antibody production in vivo and acts directly on B cells in vitro to increase survival and hence antibody production. Journal of immunology (Baltimore, Md. : 1950). Akai PSMosmann TR (1999 Jan). Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells. Microbes and infection / Institut Pasteur. Liu MFNing QPope MMosmann TLeibowitz JDing JWFung LSRotstein OGorczynski RLevy GA (1998). Resistance of naive mice to murine hepatitis virus strain 3 requires development of a Th1, but not a Th2, response, whereas pre-existing antibody partially protects against primary infection. Advances in experimental medicine and biology. Sad SLi LMosmann TR (1997 Jul 15). Cytokine-deficient CD8+ Tc1 cells induced by IL-4: retained inflammation and perforin and Fas cytotoxicity but compromised long term killing of tumor cells. Journal of immunology (Baltimore, Md. : 1950). Li LSad SKägi DMosmann TR (1997 May 1). CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions. Journal of immunology (Baltimore, Md. : 1950). Sad SKrishnan LBleackley RCKägi DHengartner HMosmann TR (1997 Apr). Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity. European journal of immunology. Mosmann TRLi LSad S (1997 Apr). Functions of CD8 T-cell subsets secreting different cytokine patterns. Seminars in immunology. Mosmann TRLi LHengartner HKagi DFu WSad S (1997). Differentiation and functions of T cell subsets. Ciba Foundation symposium. Suarez-Pinzon WRajotte RVMosmann TRRabinovitch A (1996 Oct). Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction. Diabetes. Madsen KLTavernini MMMosmann TRFedorak RN (1996 Oct). Interleukin 10 modulates ion transport in rat small intestine. Gastroenterology. Sad SKägi DMosmann TR (1996 Oct 1). Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation. The Journal of experimental medicine. Lai YHHeslan JMPoppema SElliott JFMosmann TR (1996 May 1). Continuous administration of Il-13 to mice induces extramedullary hemopoiesis and monocytosis. Journal of immunology (Baltimore, Md. : 1950). Pope MChung SWMosmann TLeibowitz JLGorczynski RMLevy GA (1996 May 1). Resistance of naive mice to murine hepatitis virus strain 3 requires development of a Th1, but not a Th2, response, whereas pre-existing antibody partially protects against primary infection. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRSad S (1996 Mar). The expanding universe of T-cell subsets: Th1, Th2 and more. Immunology today. Krishnan LGuilbert LJRussell ASWegmann TGMosmann TRBelosevic M (1996 Jan 15). Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. Journal of immunology (Baltimore, Md. : 1950). Krishnan LGuilbert LJWegmann TGBelosevic MMosmann TR (1996 Jan 15). T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and reduced IL-10 production by placental cells. Journal of immunology (Baltimore, Md. : 1950). Sad SMosmann TR (1995 Nov 1). Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines. The Journal of experimental medicine. Mosmann TR (1995 Jun). Cytokines, differentiation and functions of subsets of CD4 and CD8 T cells. Behring Institute Mitteilungen. Chaouat GAssal Meliani AMartal JRaghupathy RElliott JFElliot JMosmann TWegmann TG (1995 May 1). IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. Journal of immunology (Baltimore, Md. : 1950). Sad SMarcotte RMosmann TR (1995 Mar). Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity. Mosmann TRSad SKrishnan LWegmann TGGuilbert LJBelosevic M (1995). Differentiation of subsets of CD4+ and CD8+ T cells. Ciba Foundation symposium. Li LElliott JFMosmann TR (1994 Nov 1). IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. Journal of immunology (Baltimore, Md. : 1950). Sad SMosmann TR (1994 Oct 15). Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. Journal of immunology (Baltimore, Md. : 1950). Simon JCMosmann TEdelbaum DSchopf EBergstresser PRCruz PD (1994 Oct). In vivo evidence that ultraviolet B-induced suppression of allergic contact sensitivity is associated with functional inactivation of Th1 cells. Photodermatology, photoimmunology & photomedicine. Mosmann TR (1994 Jul 8). Cytokine patterns during the progression to AIDS. Science (New York, N.Y.). Mosmann TR (1994). Properties and functions of interleukin-10. Advances in immunology. Lin HMosmann TRGuilbert LTuntipopipat SWegmann TG (1993 Nov 1). Synthesis of T helper 2-type cytokines at the maternal-fetal interface. Journal of immunology (Baltimore, Md. : 1950). Yang XGieni RSMosmann TRHayGlass KT (1993 Jul 1). Chemically modified antigen preferentially elicits induction of Th1-like cytokine synthesis patterns in vivo. The Journal of experimental medicine. Wegmann TGLin HGuilbert LMosmann TR (1993 Jul). Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunology today. Moore KWO'Garra Ade Waal Malefyt RVieira PMosmann TR (1993). Interleukin-10. Annual review of immunology. Bloemkolk JWGray MRMerchant FMosmann TR (1992 Jul). Effect of temperature on hybridoma cell cycle and MAb production. Biotechnology and bioengineering. Sher AGazzinelli RTOswald IPClerici MKullberg MPearce EJBerzofsky JAMosmann TRJames SLMorse HC (1992 Jun). Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunological reviews. Paul WEKishimoto TMelchers FMetcalf DMosmann TOppenheim JRuddle NVan Snick J (1992 May). Nomenclature for secreted regulatory proteins of the immune system (interleukins). WHO-IUIS Nomenclature Subcommittee on Interleukin Designation. Clinical and experimental immunology. Mosmann TR (1992). T lymphocyte subsets, cytokines, and effector functions. Annals of the New York Academy of Sciences. Sadick MDStreet NMosmann TRLocksley RM (1991 Dec). Cytokine regulation of murine leishmaniasis: interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice. Infection and immunity. Fiorentino DFZlotnik AMosmann TRHoward MO'Garra A (1991 Dec 1). IL-10 inhibits cytokine production by activated macrophages. Journal of immunology (Baltimore, Md. : 1950). Sher AFiorentino DCaspar PPearce EMosmann T (1991 Oct 15). Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRSchumacher JHStreet NFBudd RO'Garra AFong TABond MWMoore KWSher AFiorentino DF (1991 Oct). Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunological reviews. Mosmann TR (1991 Jun). Cytokines: is there biological meaning? Current opinion in immunology. Fiorentino DFZlotnik AVieira PMosmann TRHoward MMoore KWO'Garra A (1991 May 15). IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. Journal of immunology (Baltimore, Md. : 1950). Budd RCSchumacher JHWinslow GMosmann TR (1991 Apr). Elevated production of interferon-gamma and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression. European journal of immunology. Mosmann TRMoore KW (1991 Mar). The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunology today. Vieira Pde Waal-Malefyt RDang MNJohnson KEKastelein RFiorentino DFdeVries JERoncarolo MGMosmann TRMoore KW (1991 Feb 15). Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proceedings of the National Academy of Sciences of the United States of America. Kupfer AMosmann TRKupfer H (1991 Feb 1). Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells. Proceedings of the National Academy of Sciences of the United States of America. Street NEMosmann TR (1991 Feb). Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Thompson-Snipes LDhar VBond MWMosmann TRMoore KWRennick DM (1991 Feb 1). Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. The Journal of experimental medicine. Mosmann TR (1991). Role of a new cytokine, interleukin-10, in the cross-regulation of T helper cells. Annals of the New York Academy of Sciences. Mosmann TR (1991). Regulation of immune responses by T cells with different cytokine secretion phenotypes: role of a new cytokine, cytokine synthesis inhibitory factor (IL10). International archives of allergy and applied immunology. Mosmann TR (1991). Cytokine secretion patterns and cross-regulation of T cell subsets. Immunologic research. Coffman RLMosmann TR (1991 Jan). CD4+ T-cell subsets: regulation of differentiation and function. Research in immunology. Mosmann TR (1991 Jan). Cytokine secretion phenotypes of TH cells: how many subsets, how much regulation? Research in immunology. MacNeil IASuda TMoore KWMosmann TRZlotnik A (1990 Dec 15). IL-10, a novel growth cofactor for mature and immature T cells. Journal of immunology (Baltimore, Md. : 1950). Go NFCastle BEBarrett RKastelein RDang WMosmann TRMoore KWHoward M (1990 Dec 1). Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. The Journal of experimental medicine. Hsu DHde Waal Malefyt RFiorentino DFDang MNVieira Pde Vries JSpits HMosmann TRMoore KW (1990 Nov 9). Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science (New York, N.Y.). Mosmann TRSchumacher JHFiorentino DFLeverah JMoore KWBond MW (1990 Nov 1). Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay. Journal of immunology (Baltimore, Md. : 1950). Moore KWVieira PFiorentino DFTrounstine MLKhan TAMosmann TR (1990 Jun 8). Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science (New York, N.Y.). Street NESchumacher JHFong TABass HFiorentino DFLeverah JAMosmann TR (1990 Mar 1). Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. Journal of immunology (Baltimore, Md. : 1950). Fong TAMosmann TR (1990 Mar 1). Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines. Journal of immunology (Baltimore, Md. : 1950). Finkelman FDHolmes JKatona IMUrban JFBeckmann MPPark LSSchooley KACoffman RLMosmann TRPaul WE (1990). Lymphokine control of in vivo immunoglobulin isotype selection. Annual review of immunology. Street NEMosmann TR (1990). IL4 and IL5: the role of two multifunctional cytokines and their place in the network of cytokine interactions. Biotherapy (Dordrecht, Netherlands). Fiorentino DFBond MWMosmann TR (1989 Dec 1). Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. The Journal of experimental medicine. Fong TAMosmann TR (1989 Nov 1). The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. Journal of immunology (Baltimore, Md. : 1950). Bass HMosmann TStrober S (1989 Nov 1). Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation. The Journal of experimental medicine. DeKruyff RHJu STHunt AJMosmann TRUmetsu DT (1989 Apr 15). Induction of antigen-specific antibody responses in primed and unprimed B cells. Functional heterogeneity among Th1 and Th2 T cell clones. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRFong TA (1989 Jan 17). Specific assays for cytokine production by T cells. Journal of immunological methods. Brown KDZurawski SMMosmann TRZurawski G (1989 Jan 15). A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRCoffman RL (1989). TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annual review of immunology. Mosmann TRCoffman RL (1989). Heterogeneity of cytokine secretion patterns and functions of helper T cells. Advances in immunology. Sanders VMFernandez-Botran RCoffman RLMosmann TRVitetta ES (1988 Oct). A single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cell. Proceedings of the National Academy of Sciences of the United States of America. Mosmann TR (1988 Oct). Directional release of lymphokines from T cells. Immunology today. Schumacher JHO'Garra AShrader Bvan Kimmenade ABond MWMosmann TRCoffman RL (1988 Sep 1). The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. Journal of immunology (Baltimore, Md. : 1950). Fernandez-Botran RSanders VMMosmann TRVitetta ES (1988 Aug 1). Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. The Journal of experimental medicine. Stevens TLBossie ASanders VMFernandez-Botran RCoffman RLMosmann TRVitetta ES (1988 Jul 21). Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature. Finkelman FDKatona IMMosmann TRCoffman RL (1988 Feb 15). IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. Journal of immunology (Baltimore, Md. : 1950). Coffman RLMosmann TR (1988). Isotype regulation by helper T cells and lymphokines. Monographs in allergy. Ransom JFischer MMosmann TYokota TDeLuca DSchumacher JZlotnik A (1987 Dec 15). Interferon-gamma is produced by activated immature mouse thymocytes and inhibits the interleukin 4-induced proliferation of immature thymocytes. Journal of immunology (Baltimore, Md. : 1950). Coffman RLShrader BCarty JMosmann TRBond MW (1987 Dec 1). A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization. Journal of immunology (Baltimore, Md. : 1950). Bond MWShrader BMosmann TRCoffman RL (1987 Dec 1). A mouse T cell product that preferentially enhances IgA production. II. Physicochemical characterization. Journal of immunology (Baltimore, Md. : 1950). Cherwinski HMSchumacher JHBrown KDMosmann TR (1987 Nov 1). Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. The Journal of experimental medicine. Dubois PStein PEnnist DGreenblatt DMosmann THoward M (1987 Sep 15). Requirement for BSF-1 in the induction of antigen-specific B cell proliferation by a thymus-dependent antigen and carrier-reactive T cell line. Journal of immunology (Baltimore, Md. : 1950). Cher DJMosmann TR (1987 Jun 1). Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. Journal of immunology (Baltimore, Md. : 1950). Deans JPKrowka JFMosmann TPilarski LM (1987 Apr). Antigen-specific helper factor reacts with antibody to the T-cell receptor. Journal of immunogenetics. Mosmann TRYokota TKastelein RZurawski SMArai NTakebe Y (1987 Mar 15). Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4). Journal of immunology (Baltimore, Md. : 1950). Hu-Li JShevach EMMizuguchi JOhara JMosmann TPaul WE (1987 Jan 1). B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes. The Journal of experimental medicine. Rupp FBrecher JGiedlin MAMosmann TZinkernagel RMHengartner HJoho RH (1987 Jan). T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes. Proceedings of the National Academy of Sciences of the United States of America. Mosmann TRCoffman RL (1987). Two types of mouse helper T-cell clone Implications for immune regulation. Immunology today. Zurawski SMMosmann TRBenedik MZurawski G (1986 Nov 15). Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity. Journal of immunology (Baltimore, Md. : 1950). Yokota TOtsuka TMosmann TBanchereau JDeFrance TBlanchard DDe Vries JELee FArai K (1986 Aug). Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities. Proceedings of the National Academy of Sciences of the United States of America. Mosmann TRBond MWCoffman RLOhara JPaul WE (1986 Aug). T-cell and mast cell lines respond to B-cell stimulatory factor 1. Proceedings of the National Academy of Sciences of the United States of America. Krowka JFSingh BFotedar AMosmann TGiedlin MAPilarski LM (1986 May 15). A requirement for physical linkage between determinants recognized by helper molecules and cytotoxic T cell precursors in the induction of cytotoxic T cell responses. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRCherwinski HBond MWGiedlin MACoffman RL (1986 Apr 1). Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of immunology (Baltimore, Md. : 1950). Lee FYokota TOtsuka TMeyerson PVillaret DCoffman RMosmann TRennick DRoehm NSmith C (1986 Apr). Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities. Proceedings of the National Academy of Sciences of the United States of America. Giedlin MALongenecker BMMosmann TR (1986 Feb). Murine T-cell clones specific for chicken erythrocyte alloantigens. Cellular immunology. Pringle GADodd CMOsborn JWPearson CHMosmann TR (1985 Jan). Production and characterization of monoclonal antibodies to bovine skin proteodermatan sulfate. Collagen and related research. Yokota TArai NLee FRennick DMosmann TArai K (1985 Jan). Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells. Proceedings of the National Academy of Sciences of the United States of America. Yokota TLee FRennick DHall CArai NMosmann TNabel GCantor HArai K (1984 Feb). Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells. Proceedings of the National Academy of Sciences of the United States of America. Mosmann T (1983 Dec 16). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of immunological methods. Valle GBesley JWilliamson ARMosmann TRColman A (1983 Apr 15). Post-translational fate of variant MOPC 315 lambda chains in Xenopus oocytes and mouse myeloma cells. European journal of biochemistry / FEBS. Tsui FMahuran DJLowden JAMosmann TGravel RA (1983 Apr). Characterization of polypeptides serologically and structurally related to hexosaminidase in cultured fibroblasts. The Journal of clinical investigation. Lee JSDombroski DFMosmann TR (1982 Sep 28). Specificity of autoimmune monoclonal Fab fragments binding to single-stranded deoxyribonucleic acid. Biochemistry. Hozumi NWu GMurialdo HBaumal RMosmann TWinberry LMarks A (1982 Jul). Arrangement of lambda light chain genes in mutant clones of the MOPC 315 mouse myeloma cells. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRLongenecker BM (1982 Jan). The high background immune reactivity of mice to polymorphic determinants on xenogeneic erythrocytes: theoretical and practical implications. Journal of immunology (Baltimore, Md. : 1950). Maclean GDMosmann TRAkabutu JJLongenecker BM (1982). Preference of the early murine immune response for polymorphic determinants on human lymphoid-leukemia cells and the potential use of monoclonal antibodies to these determinants in leukemia-typing panel. Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine. Bleackley RCCaplan BHavele CRitzel RGMosmann TRFarrar JJPaetkau V (1981 Dec). Translation of lymphocyte mRNA into biologically-active Interleukin 2 in oocytes. Journal of immunology (Baltimore, Md. : 1950). Mackie EBMosmann TRBryan LELongenecker BM (1981 Jul). A strong, specific response of mice to serotype-specific antigenic determinants of Neisseria meningitidis, analyzed with mouse monoclonal antibodies. Journal of immunology (Baltimore, Md. : 1950). Lee JSLewis JRMorgan ARMosmann TRSingh B (1981 Apr 10). Monoclonal antibodies showing sequence specificity in their interaction with single-stranded DNAs. Nucleic acids research. Longenecker BMMosmann TR (1981). Nomenclature for chicken MHC (B) antigens defined by monoclonal antibodies. Immunogenetics. Longenecker BMMosmann TR (1981). Structure and properties of the major histocompatibility complex of the chicken. Speculations on the advantages and evolution of polymorphism. Immunogenetics. Mosmann TRGallatin MLongenecker BM (1980 Sep). Alteration of apparent specificity of monoclonal (hybridoma) antibodies recognizing polymorphic histocompatibility and blood group determinants. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRWilliamson AR (1980 Jun). Structural mutations in a mouse immunoglobulin light chain resulting in failure to be secreted. Cell. Williamson ARSinger HHSinger PAMosmann TR (1980 Apr). The value of tunicamycin for studies on immunoglobulin biosynthesis. Biochemical Society transactions. Longenecker BMMosmann TR (1980). Restricted expression of an MHC alloantigen in cells of the erythroid series: a specific marker for erythroid differentiation. Journal of supramolecular structure. Longenecker BMMosmann TR (1980). "Natural" antibodies to chicken MHC antigens are present in mice, rats, humans, alligators and allogeneic chickens. Immunogenetics. Wegmann TGMosmann TRCarlson GAOlijnyk OSingh B (1979 Sep). The ability of the murine placenta to absorb monoclonal anti-fetal H-2K antibody from the maternal circulation. Journal of immunology (Baltimore, Md. : 1950). Mosmann TRBaumal RWilliamson AR (1979 Jul). Mutations affecting immunoglobulin light chain secretion by myeloma cells. I. Functional analysis by cell fusion. European journal of immunology. Mosmann TRGravel YWilliamson ARBaumal R (1978 Feb). Modification and fate of J chain in myeloma cells in the presence and absence of polymeric immunoglobulin secretion. European journal of immunology. Singer PAMosmann TRWilliamson AR (1976 Sep). Genetic control of immunoglobulin production by individual cell lines. Annales d'immunologie. Hudson JBMisra VMosmann TR (1976 Jul 1). Properties of the multicapsid virions of murine cytomegalovirus. Virology. Hudson JBMisra VMosmann TR (1976 Jul 1). Cytomegalovirus infectivity: analysis of the phenomenon of centrifugal enhancement of infectivity. Virology. Mosmann TBaumal R (1976 Mar). Macroscopic cloning assay using complement fixation to isolate secretion variants of myeloma cells. Journal of immunological methods. (1976). W.H.O./I.A.B.S. symposium on the measurement of the number of organisms in bacterial vaccines. Geneva, 2-3 October 1975. Statement on the determination of opacity of bacterial suspensions for vaccine. Journal of biological standardization. Matos L (1976). [Delayed primary wound treatment]. Magyar traumatológia, orthopaedia és helyreállító sebészet. Mosmann TBaumal R (1975 Oct). Synthesis but not secretion of J chain by variant mouse myeloma cells which lose alpha-chain-synthesizing ability. Journal of immunology (Baltimore, Md. : 1950). Anderson TRSlotkin TA (1975 Aug 15). Maturation of the adrenal medulla--IV. Effects of morphine. Biochemical pharmacology. Mosmann TRHudson JB (1974 Nov). Structural and functional heterogeneity of the murine cytomegalovirus genome. Virology. Mosmann TRHudson JB (1973 Jul). Some properties of the genome of murine cytomegalovirus (MCV). Virology. Woods DRMosmann TRHanson SHendry DA (1971 Nov). Pigmentation and acriflavine resistance in Serratia marcescens. Journal of bacteriology.