In the News Anna Bird Awarded CTSI Trainee Pilot Grant Anna Bird, a graduate student working toward her doctorate in the laboratory of Jennifer Anolik, M.D., Ph.D. was awarded a CTSI Trainee Pilot Grant to study the immunologic mechanisms underlying systemic lupus erythematosus. 12th Annual Lupus Golf Tournament Thank you to the Formicola Family for organizing this fundraiser which was held on August 17, 2015 at the Pinewood Country Club. Our own Jennifer Anolik, M.D., Ph.D., a specialist in lupus and lupus researcher, participated in the tournament. Jennifer Anolik, M.D., Ph.D. Inducted into the American Society of Clinical Investigation Dr. Anolik will be inducted into the American Society of Clinical Investigation (ASCI) this weekend in Chicago. This membership is a recognition achieved by only a small subset of physician scientists. For those who are not familiar with this organization, ASCI comprises more than 3,000 physician-scientists from all medical specialties elected to the Society for their outstanding records of scholarly achievement in biomedical research. The ASCI represents active physician-scientists who are at the bedside, at the research bench, and at the blackboard. Many of its senior members are widely recognized leaders in academic medicine. Only 80 other physicians in the country are elected into this society annually. What’s more, only 18 other physicians from the University of Rochester have ever been elected for this honor. Members are elected to the Society for their outstanding records of scholarly achievement in biomedical research and members must be 50 years old or younger. Jennifer Anolik, M.D., Ph.D. Receives Competitive NIH Grant to Study Rheumatoid Arthritis A research team at the medical center led by Dr. Jennifer Anolik was chosen by the National Institutes of Health to become one of 11 NIH Accelerating Medicines Partnership in Rheumatoid Arthritis (RA) and Lupus Network. The research team will focus on RA, collecting joint tissue and analyzing how immune cells communicate with bone cells. The team hopes to better understand how these cells communicate in order to uncover novel approaches to halting or slowing the series of events the lead to inflammation. John Looney, M.D. Installed as Rosenfeld Distinguished Professor On June 20, 2014, John Looney, M.D. was installed as the Dr. Stephen I. Rosenfeld and Elise A. Rosenfeld Distinguished Professor in Allergy and Clinical Immunology at a celebration in the company of his colleagues and friends at the Genesee Valley Club in Rochester. Dr. Looney is board certified in allergy and immunology as well as rheumatology, infectious diseases and internal medicine and has been on the faculty since 1984. Dr. Looney is a compassionate clinician, has mentored countless students, residents and fellows and has a distinguished career in basic and clinical research. Dr. Stephen Rosenfeld and Dr. John Looney Dr. John Looney is one of six URMC faculty members to begin new research projects Six URMC faculty members are beginning new research projects funded by Clinical and Translational Science Institute pilot awards for 2014-2015. The CTSI's pilot program offers faculty members one-year awards for up to $50,000 to facilitate new research and future funding. Dr. Looney's project will examine the role of the gut microbiome in preventing allergic diseases. Dr. Ritchlin Recieves CTSI Grant In the hopes of advancing treatments for psoriatic arthritis, or even preventing it, researchers at UR Medicine are now studying a specific molecule on the surface of the cells that lead to the crippling condition. The research, led by Christopher Ritchlin, M.D., M.P.H., Chief of the Department of Allergy/Immunology, and Rheumatology, is supported by a 2-year, $250,000 incubator grant from the Clinical and Translational Science Institute (CTSI), which began on July 1. "If we can identify targets that we can inhibit, we can block the formation of these bone-resorbing cells," said Ritchlin. "We can develop new medications to stop bone-resorbing diseases like arthritis, osteoporosis, metastatic cancer." Minsoo Kim , Associate Professor of Microbiology and Immunology, and Brendan Boyce, Professor of Pathology and Laboratory Medicine, are co-principal investigators. Read more in Sean Dobbins' article at CTSI Stories. Recently Published Journal Articles Patients with rheumatoid arthritis in clinical remission manifest persistent joint inflammation on histology and imaging studies Anandarajah A, Thiele R, Giampoli E, Monu J, Seo GS, Feng C, Ritchlin CT. J Rheum. 2014 Nov;41(11):2153-60. doi: 10.3899/jrheum.140411. Epub 2014 Oct 1. Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche Wang W, Rangel-Moreno J, Owen T, Barnard J, Nevarez S, Ichikawa HT, Anolik JH. J Immunol. 2014 Apr 1;192(7):3011-20. doi: 10.4049/jimmunol.1302003. Epub 2014 Feb 26. Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan MJ, Anolik JH.