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Central Nervous System Metastasis Program

UR Medicine / Neurosurgery / Services / Central Nervous System Metasis Program / Clinical Trials

 

Clinical Trials

Clinical Trials

CBRT20074 / A071701 / Nimish Mohile

This trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such as abemaciclib, paxalisib, and entrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Genetic testing may help doctors tailor treatment for each mutation.

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