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National Dental Practice Based Research Network

EIOH is part of national effort that will transform oral health and clinical practice throughout the U.S.  Read more
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Developing Optimal Implant Designs & Surface Properties

Dental implants are widely used to replace missing teeth. Our research focuses on developing optimal implant designs and surface properties to improve wound  healing events and to ensure a long lasting rehabilitation. In particular, we are interested in tailored approaches to create well defined topographical features with desired chemical composition. In addition to the development of novel surface modifications, our lab is focusing on the interplay between surface properties and wear during implant placement.

Surface Roughness Parameters as a Predictor of Wear During Implant Placement

Biomaterial surface modifications are used to trigger particular tissue responses. In common, most surface modification of metal implants will increase the roughness. The surface surface features created may not withstand the implant placement procedure and detach from the surface. Surface roughness parameters are used to provide numerical data to evaluate and estimate the overall release of particles from the implant surface.

Effect of Titanium Particles on Early Bone Loss

Early bone loss is a common finding after implant placement and  is considered a normal event associated with wound healing. We have recently demonstrated that surgical sites pre-treated with Titanium particles demonstrated increased bone resorption resulting in early bone loss compared to control sites in the rabbit tibia. Our laboratory will investigate the mechanisms behind early bone loss triggered by titanium particles in vivo to establish novel approaches to prevent complications.


Environmental Agents and Oral Health

  • Recently Completed
    Mercury Vapor from Amalgam and Methylmercury Co-Exposure on Neurodevelopment

    The aim of the project is to quantify the level of risk for adverse neurodevelopmental outcomes attributable to prenatal and postnatal co-exposure to mercury vapor from dental amalgam and methylmercury from fish consumption.  This multinational collaborative project will capitalize on the availability of mothers and children participating in the well-characterized Seychelles Child Development Nutrition Study.
    Sponsor: NIH/NIEHS/NIDCR
    Award number: R01 ES015578
    Principal Investigator: Gene E. Watson II, D.D.S., M.S., Ph.D.

Health Services Research

  • Recently Completed
    Oral Health Surveillance

    To conduct oral health surveillance of preschool and elementary school children in collaboration with the Monroe County Department of Health.
    Principal Investigator: Sangeeta Gajendra, D.D.S., M.P.H

  • Recently Completed
    Utility of Teledentistry to Reduce Oral Disease Burden in Preschool Children

    An exploration of teledentistry, an approach that uses an intraoral camera to image teeth and tooth surfaces. To determine if teledentistry is useful in reducing oral disease burden in preschool inner city children, an intervention study will be conducted in inner-city childcare centers participating in Health-e-Access project.
    Sponsor: NIH
    Award number : K23 DE017230
    Principal Investigator: Dorota Kopycka-Kedzierawski D.D.S., M.P.H.

Craniofacial Development

  • Genetic basis of cleft lip and palate
  • Molecular genetic analysis of craniofacial development
  • Genetic reg. network in craniofacial development

Salivary Diagnosis and Therapy

  • Radioprotection by targeted SiRNA delivery to salivary glands
  • Salivary gland precursor cells

Skeletal, Alveolar and Dental Tissue Regeneration

  • Mammary stem cells in development and cancer

Periodontal Diagnosis and Therapy

Periodontal Diagnosis and Therapy

Clinical Research

Implants, dental materials, lasers

Our Latest Research Publications

View our latest dental research publications

More Research

Center for Oral Biology