Recent Graduates

Role of EVI1 in Hematopoietic Stem Cell Differentiation and Leukemia

Advisor: David Yule, Ph.D. & Archibald Perkins, M.D., Ph.D.

Now: TRIUMPH Postdoctoral Fellow at MD Anderson Cancer Center, Houston TX

Chronic PKCβII Activation Inhibits IKs Channel Membrane Localization via Phosphatidylinositol 4-phosphate: Implications for Long-QT1 Treatment

Advisor: Coeli Lopes, Ph.D.

Development of Acoustically-Modified Collagen-Based Biomaterials for Regenerative Medicine Applications

Advisor: Denise Hocking, Ph.D.

Now: Postdoctoral Fellow at the Department of Pharmacology and Physiology, University of Rochester, Rochester, NY

Neutrophil Elastase and GPNMB as Novel Potential Therapeutic Targets in a Tsc2-null Mouse Model for Lymphangioleiomyomatosis (LAM) Tumor Growth

Advisor: Stephen Hammes, M.D., Ph.D.

Now: Postdoctoral Fellow, Department of Medicine at University of Rochester, Rochester, NY

Biophysical and Molecular Mechanisms for QRS- and QTc-Interval Prolongation in Mice with Cardiac Expression of Expanded CUG repeat RNA

Advisor: Robert Dirksen, Ph.D.

Now: J.D. Candidate at UNH Franklin Pierce School of Law, Concord, NH

The Role of PLC-Dependent Hydrolysis of Phosphatidylinositol 4-Phosphate in Signaling and Disease

Advisor: Alan Smrcka, Ph.D.

Now: Scientist at Riparian Pharmaceuticals, Watertown, MA

Cooperative and Mechanistic Roles of Mecom in Hematopoiesis

Advisor: Robert Freeman, Ph.D. & Archibald Perkins, M.D., Ph.D.

Now: Postdoctoral Associate at Department of Biomedical Genetics/Cancer Center, University of Rochester, Rochester, NY

The Importance of G Protein Signaling in Immune Cell Function: A Novel Role for Active G Protein in Cell Adhesion and Migration and the Therapeutic Potential of Targeting G in Inflammation

Advisor: Alan Smrcka, Ph.D.

Now: Medical Writer at INVIVO Communications, Toronto, Ontario, Canada

Targeting the c-Cbl Tumor Suppressor Protein as a Novel Therapeutic Approach in Overcoming Acquired Tamoxifen Resistance in Luminal Breast Cancer

Advisor: Mark Noble, Ph.D.

Now: Scientific Writer at Bayer Corporation, Whippany, NJ

Region-specific Proteolysis Differentially Regulates Inositol 1,4,5-trisphosphate Receptor Activity

Advisor: David Yule, Ph.D.

Now: Postdoctoral Research Fellow at New York University, New York, NY

Mitochondrial Metabolism in Cardiac Ischemia-Reperfusion Injury

Advisor: Paul Brookes, Ph.D.

Now: Medical-Scientist Training Program at University of Rochester

The Role of Non-canonical Wnt Signaling in Heart Development and Repair

Advisor: Ethan Cohen, Ph.D.

Now: Postdoctoral Fellow at Columbia University, New York, NY

The Bone Microenvironment in the Setting of Acute Injury and Aging

Advisor: Laura Calvi, M.D.

Now: ORISE Fellow/Subject Matter Expert at Biomedical Advanced Research Development Authority, U.S. Department of Health and Humans Services, Washington, DC

Transglutaminase 2 Role in Neurological Disease and Injury: Alterations in Proliferation, Migration, and Metabolism

Advisor: Gail Johnson, Ph.D

Now: Postdoctoral Fellow at AMGEN, Cambridge, MA

Phosphorylation Regulates Molecular Chaperoning and GEF Functions of Ric-8A in Heterotrimeric G-protein Signaling

Advisor: Robert Freeman, Ph.D.

Now: Postdoctoral Research Associate at Stanford University, Stanford, CA

Linking the cytoskeleton to transcription: A role for myocardin-related transcription factors in heart development and disease

Advisor: Eric Small, Ph.D.

Now: Postdoctoral Research Fellow at Boston Children’s Hospital at Harvard Medical School, Boston, MA

Structural and Functional Impact of Mitochondrial Ca2+ Signaling in Skeletal Muscle

Advisor: Robert Dirksen, Ph.D.

Now: Research Scientist at Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA

Short- and Long-term Roles for Orai1 in Skeletal Muscle Structure and Function

Advisor: Robert Dirksen, Ph.D.

Now: Postdoctoral Fellow at Department of Pathology, Children’s Hospital of Philadelphia, Philadelphia, PA

Unique Regulatory Properties of Heterotetrameric Inositol 1,4,5-trisphosphate Receptors Revealed by Studying Concatenated Receptor Constructs

Advisor: David Yule, Ph.D.

Now: Regulatory Scientist at Camargo Pharmaceutical Services, Durham, NC

Regulation of Endothelial Cell Behavior and Vascular Function by Krev Interaction Trapped Protein 1 (KRIT1)

Advisor: Angela Glading, Ph.D.

Now: Scientist at Biogen Inc., Cambridge, MA

The Role of PIN1 in Neuronal Programmed Cell Death Following Trophic Factor Deprivation

Advisor: Robert Freeman, Ph.D.

Now: Resident, Anesthesiology at University of Rochester, Rochester, NY

Ca2+ Signaling Involved in Pancreatic Stellate Cell Proliferation and Identification of a Potential Therapeutic Target

Advisor: David Yule, Ph.D.

Now: Senior Scientist, Research & Development at Becton Dickinson (BD) Medical Technology, Franklin Lakes, NJ

Cell-type and Stimulus-specific Regulation of JUN and BIM by EGLN3 in Multiple Models of Neuronal Death

Advisor: Robert Freeman, Ph.D.

Regulation, Function, and Mechanisms of Cyclic Nucleotide Phosphodiesterase 1C in Pathological Cardiac Remodeling and Dysfunction

Advisor: Chen Yan, Ph.D.

Now: Postdoctoral Associate, Department of Medicine at University of Colorado-Denver, Aurora, CO

Heterotrimeric G-Protein α Subunit Chaperone Ric-8A as a Novel Target for Cancer Therapeutics

Advisor: Gregory Tall, Ph.D.

Now: Research Scientist at Novartis Institute for Biomedical Research, Cambridge, MA

Activation of Adhesion G Protein-coupled Receptors by a Tethered Agonist: Mechanism of Action and Pharmacological Modulation

Advisor: Gregory Tall, Ph.D.

Now: Postdoctoral Fellow at The Scripps Research Institute-Florida Campus, Jupiter, FL

The Role of STXBP5, VAMP8, and SNAP23 in Endothelial Exocytosis

Advisor: Charles Lowenstein, M.D.

Now: Research Fellow at Broad Institute of Massachusetts General Hospital, Cambridge, MA