Recent Graduates

Differential Regulation of Opioid Receptor Signaling via Gα Proteins

Advisor: Jean Bidlack, Ph.D.

Now: Postdoctoral Fellow at Biogen, Cambridge, MA

Regulation, Function and Mechanism of Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

Advisor: Chen Yan, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester, NY

FGF21 Reduced Morphine Preference and the Development of Acute Antinociceptive Tolerance and Physical Dependence

Advisor: Jean Bidlack, Ph.D.

Now: Preclinical Scientist at Akero Therapeutics Inc., Boston, MA

Advisor: Angela Glading, Ph.D.

Now: Research Scientist at Vertex Pharmaceuticals, Boston, MA

Functional Analysis of Disease-associated Mutations in the Inositol 1,4,5-Trisphosphate Receptor

Advisor: David Yule, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester, NY

Now: Postdoctoral Fellow at Stanford University, Stanford, CA

Optogenetic Control of Mitochondria Alters Cellular Energy Sensing and Hypoxia Resistance

Advisor: Andrew Wojtovich, Ph.D.

Now: Postdoctoral Fellow at University of Washington, Seattle, WA

Role of EVI1 in Hematopoietic Stem Cell Differentiation and Leukemia

Advisor: Archibald Perkins, M.D., Ph.D. & David Yule, Ph.D.

Now: TRIUMPH Postdoctoral Fellow at MD Anderson Cancer Center, Houston TX

Chronic PKCβII Activation Inhibits IKs Channel Membrane Localization via Phosphatidylinositol 4-phosphate: Implications for Long-QT1 Treatment

Advisor: Coeli Lopes, Ph.D.

Now: Postdoctoral Fellow at M.D. Anderson Cancer Center, Houston, TX

Understanding Molecular Mechanisms of G-protein subunit βγ Activation of Downstream Effectors

Now: Postdoctoral Researcher at Purdue University, West Lafayette, IN

Development of Acoustically-Modified Collagen-Based Biomaterials for Regenerative Medicine Applications

Advisor: Denise Hocking, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester, NY

Neutrophil Elastase and GPNMB as Novel Potential Therapeutic Targets in a Tsc2-null Mouse Model for Lymphangioleiomyomatosis (LAM) Tumor Growth

Advisor: Stephen Hammes, M.D., Ph.D.

Now: Postdoctoral Fellow at UT Southwestern, Dallas TX

Biophysical and Molecular Mechanisms for QRS- and QTc-Interval Prolongation in Mice with Cardiac Expression of Expanded CUG repeat RNA

Advisor: Robert Dirksen, Ph.D.

Now: J.D. Candidate at UNH Franklin Pierce School of Law, Concord, NH

The Role of PLC-Dependent Hydrolysis of Phosphatidylinositol 4-Phosphate in Signaling and Disease

Advisor: Alan Smrcka, Ph.D.

Now: Scientist at Riparian Pharmaceuticals, Watertown, MA

Cooperative and Mechanistic Roles of Mecom in Hematopoiesis

Advisor: Robert Freeman, Ph.D. & Archibald Perkins, M.D., Ph.D.

Now: Scientist, Translational Biology at Constellation Pharmaceuticals, Cambridge, MA

The Importance of G Protein Signaling in Immune Cell Function: A Novel Role for Active G Protein in Cell Adhesion and Migration and the Therapeutic Potential of Targeting G in Inflammation

Advisor: Alan Smrcka, Ph.D.

Now: Sr. Medical Writer at McCann Health Medical Communications, Toronto, Ontario, Canada

Targeting the c-Cbl Tumor Suppressor Protein as a Novel Therapeutic Approach in Overcoming Acquired Tamoxifen Resistance in Luminal Breast Cancer

Advisor: Mark Noble, Ph.D.

Now: Assistant Scientific Director of Global Medical Affairs at AbbVie Inc., Chicago, IL

Region-specific Proteolysis Differentially Regulates Inositol 1,4,5-trisphosphate Receptor Activity

Advisor: David Yule, Ph.D.

Now: Postdoctoral Research Fellow at New York University, New York, NY

Mitochondrial Metabolism in Cardiac Ischemia-Reperfusion Injury

Advisor: Paul Brookes, Ph.D.

Now: Resident, Internal Medicine at Icahn School of Medicine at Mount Sinai, New York, NY