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News & Events

In the Division

Dr. Thu Le Receives Award from ASN

July 27, 2020

Thu H. Le, M.D., F.A.H.A., professor of Medicine and Chief of the Division of Nephrology, has been given the American Society of Nephrology Midcareer Mentor Award. This award recognizes individuals who have made contributions to the kidney community through the mentorship and development of other clinicians or researchers. This award recognizes those who have inspired others to pursue nephrology and become leaders in the transformation of healthcare through innovations in research, education, and practice.

Dr. Le is John J. Kuiper Distinguished Professor of Medicine and Chief of the Division of Nephrology at the University of Rochester. As a clinical investigator, she is dedicated to patient care as well as research. She served on the study sections for the American Heart Association and the National Kidney Foundation, and was a regular member of the NIH Genetics of Health and Disease Study Section from 2012-2018.

Dr. Le has mentored dozens of students and trainees, and has guided numerous early career faculty in order to help them achieve success. Her passion for mentorship and dedication to promoting the careers of others have garnered numerous awards for teaching and training excellence, and helped many physician scientists launch successful careers.

Coordinating Coronavirus Research: Creating Options for Our Sickest COVID-19 Patients

July 14, 2020

When the first COVID-19 cases hit the University of Rochester Medical Center’s ICU back in March of 2020, there were no proven treatments available, but experimental therapies were cropping up around the world. Quickly, a team of URMC clinicians and researchers mobilized to bring the most promising clinical trials - that address the broadest swath of patients’ needs - to URMC. Since then, URMC has joined three clinical trials that provide extra treatment options for some of the sickest COVID-19 patients.

COVID-19 causes a wide range of outcomes: some infected people never show a single symptom, while many battle the disease for weeks in the ICU. The difference between those outcomes seems to lie in a careful balance of the immune response. In the beginning of the disease, the immune system helps fight off the virus. But for those who land in the hospital, this early, helpful immune response gives way to uncontrolled over-activation of the immune system, causing system-wide inflammation and severe complications. 

The three COVID-19 inpatient clinical trials currently running at URMC attack the disease at both ends of this balance. 

“Our goal has always been to promote effective therapies through clinical trials,” said Martin Zand, M.D., Ph.D., Professor of Medicine in Nephrology, senior associate dean for Clinical Research and co-director of the Clinical & Translational Science Institute. “Our team is working hard to make sure that the trials we bring to URMC have the greatest chance of benefiting our own patients, and significantly advancing the science of COVID-19 to benefit patients around the world.”

Study by Thu Le Highlights Diet-Gene Interactions in Kidney Disease

November 10, 2019

Research by Thu H. Le, M.D., F.A.H.A., professor of Medicine and Chief of the Division of Nephrology, suggests that the benefits of a dietary compound on kidney health may depend on an individual's genetics. Published in JASN (Journal of the American Society of Nephrology), the study may be helpful for tailoring interventions to prevent or treat kidney disease. A summary of the study appears in the research news aggregate service, Newswise.