A clinical trial is a research study involving human volunteers, and is designed to answer specific health questions. Carefully conducted clinical trials are the safest and fastest way to find effective treatments, and new ways to improve health.
You can search for all studies that are currently enrolling participants at the University of Rochester by typing in keywords in the search box below. If you don’t find a study that interests you right now, consider signing up for our Volunteer Registry, which will notify you of future studies.
Examining the Quality of Life of People with Sesame Allergy
Lead Researcher: Bushra Tbakhi
The purpose of this study is to better understand individuals' and families' experiences
with having (or having a child or children) with Ig-E-mediated sesame allergy and
how managing sesame allergy affects your quality of life. We hope that by investigating
the effects of the Food Allergy Safety, Treatment, Education, and Research (FASTER)
Act on individuals' quality of life, we can gain a better understanding of its impact
and determine if it has been beneficial. This knowledge will enable us, as medical
professionals, to advocate more effectively to policymakers.
If you decide to take part in this study, you will be asked to complete 1 survey consisting
of 6 parts that will take about 10 minutes to complete. The surveys will collect
your demographic information, ask questions about how sesame allergies affect your/your
child’s quality of life, before and after the FASTER Act / January 2023.
You can participate if you are 18 years or older with a sesame allergy or the parent
of a child with a sesame allergy. If you are interested click on the link below.
View Study Details
Parent Cafe Study for Caregivers of Children with Medical Complexity
Lead Researcher: Nathaniel Bayer
We are starting peer and emotional support group sessions for caregivers of infants
with medical complexity. We are looking for interested parents and caregivers to participate
in our research and share their experience and perspective. A child with medical complexity
means that a child has/had 2 or more long-term diagnoses and uses/used medical devices
(like a feeding tube or tracheostomy).
Depending on the status and age of your child, you could either help us design the
support groups, lead the support groups, or participate in the support groups as an
attendee. Families with different diagnoses, outcomes, racial and ethnic backgrounds,
genders, sexual orientations, religions, geographic regions and physical abilities
all provide important insight and perspective. We are recruiting caregivers of children
who have fully recovered, have recovered with ongoing needs, are undergoing treatment,
or have passed away. Your lived experience and perspective matters.
View Study Details
Social Engagement Coaching for Caregivers
Lead Researcher: Kathi Heffner
Taking care of a loved one who has dementia can become increasingly difficult. Over
time, people can experience more stress as they adjust to their progressing role as
caregiver.
The purpose of this study is to evaluate the effects of the ‘Social Engage’ coaching
program on dementia caregivers, and to determine if a computer-based planning tool
can further improve program effects.
The study will also examine how subjective social connectedness may relate to the
ways in which people respond to social cues.
The Social Engage program involves up to nine 30-minute virtual sessions (such as
via Zoom) conducted over 8-10 weeks. Sessions are flexible and individualized to help
you enhance your relationships and improve well-being while managing caregiving stress.
Participation also involves two in-person study visits, one before and one after completing
the Social Engage program. Visits are flexibly scheduled and parking is free.
Study visits involve answering some questions about yourself, including your mood
and stress, and what caregiving has been like for you. Visits also include some computer-based
tasks.
View Study Details
Staccato Alprazolam for Seizure Rescue
Lead Researcher: Thomas Wychowski
Epilepsy is a brain disorder characterized by recurrent seizures. It can occur as
a result of a brain injury, a structural brain lesion, as a part of many medical diseases,
or it may be something someone is born with. When seizures are not well controlled,
patients might experience seizure emergencies and have a need for acute treatment
in addition to their regular medicines. After patient's seizure types are evaluated
and approved, they will be trained on using the Staccato alprazolam device at home
for prolonged seizures. Study involves enrolling a study partner (family member, caregiver)
to participate in the study with the patient. Patients aged 12 and older with focal
or generalized epilepsy who have long seizures are eligible to participate.
View Study Details
UBRT21040 / Early START / Sara Hardy
Lead Researcher: Sara Hardy
High grade gliomas (HGGs) are rapidly progressive brain tumors resulting in death
for most patients between 6 months and 2 years after diagnosis. It is important for
patients with HGG to discuss and document their wishes at the end of life. However,
many of these patients experience early changes in cognition which impede their decision-making.
For this reason, these patients should have early discussions with their providers.
However, implementation of this remains challenging in clinical practice.
In this study, we will create an Early STructured Advanced care Referrals by Telehealth
(Early START) visit for patients soon after their initial oncology visit. A checklist
and pre-visit guide were developed to help guide the visit for both the provider and
patient. Providers will receive special training in running these visits. Caregivers
and/or family members will be encouraged to participate. Visits will be done using
video or telephone and recorded. For patients who do not have access to technology
for these visits, it will be provided. After the visit, patients, caregivers and/or
family who participated, and providers will fill out surveys to address feasibility
of having these extra visits and improve the visits for future. Patients will be followed
until death. Caregivers and/or family who participated will be asked about whether
end of life was in line with the patient's wishes. We will also use the patient's
medical record to assess other aspects of end of life. We will compare end of life
outcomes with other similar patients treated at our center.
View Study Details
UCCS19102 / MAAT-G JIT (Breast) / Magnuson
Lead Researcher: Allison Magnuson
Cancer-related cognitive dysfunction (CRCD) affects up to 75% of patients receiving
chemotherapy and older adults are at greater risk of developing CRCD, which can negatively
affect their functional independence and quality of life. Memory and Attention Adaptation
Training (MAAT) is a promising treatment for CRCD that improves perceived cognition
in younger cancer survivors, but needs to be adapted for older adults to address their
unique needs. The proposed study will adapt MAAT for older adults using feedback from
key stakeholders (older adults with cancer and their caregivers), and subsequently
test the ability of MAAT to improve or maintain cognition for older adults with breast
cancer receiving adjuvant chemotherapy.
View Study Details
UCCS21065 / Dyadic Life Review / Lee Kehoe
Lead Researcher: Lee Kehoe
The purpose of this study is to test the feasibility of a telehealth Dyadic Life Review
(DLR), adapted from individual Life Review Therapy, with caregivers of older adults
with advanced cancer, including those with Mild Cognitive Impairment (MCI). The study
will enroll 20 dyads of caregivers and older patients with advanced cancer and 20
dyads of caregivers and patients with advanced cancer and Mild Cognitive Impairment
(MCI).
View Study Details
UOCPC22010 / UR-GOAL 2 / Kah Poh Loh
Lead Researcher: Kah Poh Loh
The objective of this study is to conduct a pilot randomized trial to evaluate the
preliminary efficacy of the UR-GOAL tool vs. usual care in improving shared decision
making and communication between 100 older patients with AML and their oncologists.
View Study Details