Current Trainees in the Center for RNA Biology
Current Trainees in the Center for RNA Biology
Post-Doctoral Fellows and Students
Research Interest:
Investigating mechanisms that regulate transcription during terminal erythroid maturation
Research Interest:
Transcriptional and epigenetic regulation of hematopoietic cell lineage differentiation
Research Interest:
Awarded a K00/R01 Pathway to Independence Award
Research Interest:
Investigating differential intron sensitivity to PUF60, a gene that is deleted or amplified in developmental syndromes and cancers
Research Interest:
The Effect of Integrator Subunit 11 Mutations on Integrator Function and Neuronal Development
Research Interest:
Determining the role of FAM120A in mRNA Post transcriptional Control and its regulation by uORF and m6A
Research Interest:
Translational control and metabolism
Research Interest:
Suppression of cerebral cavernous malformation nonsense mutation using anti-codon edited tRNAs
Research Interest:
Development of Tools and tRNA-based Therapeutics for Rescue of PTC-derived Disease and Elongation Efficiency of CFTR
Research Interest:
Single-molecule studies of translation inhibitors and ribosome collision
Research Interest:
The Human Integrator Complex is Required for HSV-1 Infection
Research Interest:
Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 Mutations
Research Interest:
HEXIM1 Integrates Transcriptional Stress and Cell Cycle Arrest Following Dual Disruption of Integrator and NELF
Research Interest:
Modeling the effects of cancer-associated spliceosome mutations and identifying driving intronic features using deep-learning neural networks
Research Interest:
Developing novel thermodynamic parameters for RNA folding stability in simulated cellular environments to improve the accuracy of RNA secondary structure predictions.
Research Interest:
A partition function approach to modeling RNA optical melting curves
Research Interest:
Context Dependent Structural Changes of Internalized GPCR Signaling Centers
Research Interest:
Translational regulation of cardiac aging process in cardiac myocytes and fibroblasts; translation elongation and termination; protein science and biochemistry
Research Interest:
A 2.49Å cryo-electron microscopy structure of CRISPR-associated heptameric membrane pore BpyCsx27 reveals important lipid interactions and a hydrophobic gating mechanism
Research Interest:
Using All-Atom Simulations to Estimate Small Molecule-RNA Binding Affinities
Research Interest:
My research focuses on anticodon-edited tRNAs (ACE-tRNAs) for use in nonsense-mediated Duchenne muscular dystrophy using patient-derived cells and mice.
Research Interest:
Structural Analysis and Mechanism of Translation Regulation by a Class I Type III preQ1 Riboswitch from Escherichia coli
Research Interest:
Investigating Dynamic Exchanges Among Pre-mRNA Splicing Factor Complexes
Research Interest:
Structure and function analysis of a polyamine riboswitch reveals a fold exapted from the SAM-I riboswitch to reject off-target ligands for spermidine sensing in a pseudoknot interf
Research Interest:
Characterization and function of a novel Integrator-associated complex
Research Interest:
Understanding the mismatch of RNA secondary structure based on prediction models
Research Interest:
Targeting A. baumannii efflux pumps via small molecule inhibitors to improve existing antibiotic treatments' effectiveness and combat adaptive efflux-mediated drug resistance.
Research Interest:
RNAProbClust: A tool for clustering aptamer sequences from SELEX experiments
Research Interest:
Cryo-EM Data Recovery from Damaged Particles
Research Interest:
Defining the roles of 5’UTR length and secondary structure in eukaryotic translation initiation
Research Interest:
RBP PTMs, etiology, and medicine for metabolic syndrome and heart failure
Research Interest:
Probing the role of the Integrator complex during Erythropoiesis
Research Interest:
Hidden Intermediates of GPCR Signaling through Time-Resolved Cryo-EM
Research Interest:
Nuclear Inhibitor of Protein Phosphatase-1(NIPP1) regulates phosphorylation of SF3B1, a cancer-relevant pre-mRNA splicing factor
Research Interest:
Elucidating the Epigenetic Mechanisms that Regulate stress and steady-state Erythropoiesis, with the overarching goal of ameliorating symptoms in hemoglobinopathies.
Research Interest:
Role of influenza PA on host adaptation
Research Interest:
Regulation of Insulin Receptor Translation by a Conserved uORF
Research Interest:
Developing a 9-dimensional RNA-barcode to characterize RNA-containing structures
Research Interest:
Type VI CRISPR and associated bacterial anti-phage defense systems
Research Interest:
RNA Aptamers for Cardiac-Cell Specific Delivery of RNA Drugs
Research Interest:
RNA helicases & translation factors in cardiomyocytes and proteasome degradation pathway
