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Nida Meednu Pellett

Nida Meednu Pellett, Ph.D.

Ph.D. 2009
University of Rochester

Staff Scientist
Division of Allergy, Immunology and Rheumatology

Research Overview

Dr. Meednu Pellett is a research assistant professor in the lab of Jennifer Anolik, M.D., Ph.D. She joined the lab in 2011 and has been working on the role of B cells in the pathogenesis of autoimmune diseases. Her research focus is to understand the underlying pathogenic mechanisms of autoimmune diseases, specifically systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), on the role of B cells in the development and progression of these diseases. Autoimmune diseases are characterized by the presence of antibodies against self-antigens. As an antibody producing cells, the B cell is a key player in the pathogenesis of autoimmune diseases. However, B cells also have other functions beyond antibody production.  Dr. Meednu Pellett’s research focus is to investigate autoantibody independent functions of B cells including interaction with other immune cells and other relevant organ systems. Her research focus in RA is to understand the mechanism of how B cells interact with osteoclasts and osteoblasts to contribute to bone erosion process in this disease.