T32- Supported Training in Musculoskeletal Science In 2006, the CMSR initiated a formal T32-supported training program aiming to provide a comprehensive didactic and research education as well as career development mentoring to future scientists in the musculoskeletal field. Overall, the program targets the development of 1) critical laboratory skills, 2) basic orthopaedic clinical and scientific knowledge, and 3) personal and professional attributes necessary for pursuit of a career as an independent investigator. The mission statement reflects this: “To provide comprehensive training in musculoskeletal science with the aim of developing outstanding investigators in the field of orthopaedic research”. In addition to providing trainees access to a broad range of research opportunities (see the Research Programs link), the principle faculty utilize several key training components that have been highly successful since the inception of the program: A weekly CMSR-wide Lab Meeting The Foundations of Orthopaedic Science Curriculum (3 course series) Art of Science Course 6/20/16 Jennifer Jonason, PhD - "Peer-review: Being a Constructive Critic & Responding to a Critique" 6/27/16 Alayna Loiselle, PhD - "Publish or Perish: Step by Step Process for Writing a Manuscript" 7/11/16 Edward Schwarz, PhD - "Roadmap to the NIH" 7/18/16 Michael Zuscik, PhD - "The F31/F32 Application" Fellowship Guidelines 7/25/16 Susan Daiss, MDiv - "The Art of Observation in Science" 8/1/16 Tracey Baas, PhD - "Career Fate Determination" 8/8/16 Weimin Kaufamn, PhD - "Intellectual Property and Enterpreneurship" 8/15/16 Jack Daiss, PhD - "Academia vs. Industry" Four concurrently running Journal Clubs Trainee access to a Grant Writing/Specific Aims Development Core The William F. Neuman Visiting Scientist Seminar Series The Annual Center for Muscloskeletal Research Symposium Current Trainees Pre-doctoral Anna Bird (Dr. Jennifer Anolik) Sarah Catheline (Dr. Jennifer Jonason) Christopher Farnsworth (Dr. Robert Mooney) Margaret Thomas Freeberg (Dr. Hani Awad) Corey Hoffman (Dr. Laura Calvi) Sara Nowacki (Dr. Hani Awad) Post-doctoral Li Yue, PhD (Dr. John Elfar) Taketo Taguchi, PhD (Dr. Vera Gorbunova) Formal Training Activities Center Lab Meetings occur weekly on Wednesday morning. Each meeting is moderated by 2 trainees who take 30 minutes each to present either ‘dirty data’ for discussion of troubleshooting and research direction (Work in Progress) or formal presentations which provide background, hypotheses, experimental strategies, results and conclusions regarding a single project. The Foundations of Orthopaedic Science Curriculum, which was developed specifically for trainees in the CMSR, is a cornerstone of the Program. It encompasses a three course series (IND592, IND593, IND594). CMSR trainees at all levels (undergraduate, graduate & medical students, clinical residents & fellows, post-doctoral fellows), technical staff, and junior faculty attend the lectures. Journal Clubs meet on a biweekly basis. The presenter at each Journal Club meeting is a student or fellow and the paper to be discussed (not more than 6 months past publication) is chosen by the trainee in consultation with their faculty mentor. During the meeting, the presenter is responsible for providing enough background to bring the group up to speed on the specific topic and then moderates the group’s discussion of each figure and how it contributes to the overall conclusion(s) of the study. The William F. Neuman Visiting Scientist Seminar Series features invited distinguished speakers on a monthly basis. Over the past 5 years, we have been able to invite numerous internationally recognized skeletal biologists including Drs. Lawrence Raisz, Clifford Rosen, Nancy Lane, Christopher Evans, Ernesto Canalis, Mone Zaidi, David Roodman, Toshiyuki Yoneda, Larry Suva, Robert Gulberg, Tom Einhorn, Daniel Baron, Ian Cassady, Dan Gazit, Robert Heaney, Dana Gaddy, Larry Riggs, Roberto Pacifici, Greg Mundy, Robert Lindsay, Gerard Karsenty, Matt Warman, Karen Lyons, Henry Kronenberg, Jennifer Westendorf, Maurizio Pacifici, Ben Alman and numerous others. The Center for Musculoskeletal Research Symposium takes place annually at the beginning of the Fall Semester. The Symposium includes several components including a poster session for all trainees in the Center (including the T32-supported trainees) as well as trainees outside the Center performing musculoskeletal research. Plenary sessions with presentations by trainees performing meritorious research, internal faculty, and a visiting keynote speaker flank the poster session. Three trainee travel awards are announced at the end of the event to recognize outstanding research (2 pre- and 1 postdoctoral). Pre-baccalaureate Training in Musculoskeletal Science in the CMSR is structured to educate young scientists that are i) currently undergraduates in the Biology or Biomedical Engineering Departments at the University of Rochester, and ii) URM/underprivileged high school students from the Rochester City School District. In some rare cases, students also hail from other institutions around the country. The mission of the program is to provide early exposure to the basics of musculoskeletal science and facilitate undergraduate trainee involvement in cutting edge basic biomedical and clinical research. The goal is to energize the next generation of scientists in our field. Overall, the combination of these 6 elements provide trainees with an outstanding educational experience that compliments and extends the research-specific training provided by Program faculty.