Trainees

Research Interest: Define the information carriers in semen underlying Pb-induced transgenerational behavioral alterations.

Research Interest: mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding

Research Interest: Capturing the Influence of Structural Context and Solvent in Fixed-charge Force Fields for RNA

Research Interest: HIV TAR RNA Recognition by Multiple Lab-Evolved Proteins Provides Insight into Cyclic-Peptide Inhibitor Design

Research Interest: Pathomechanism of skeletal muscle weakness and degeneration in Myotonic Dystrophy

Research Interest: Elucidating guide-RNA design rules for efficient and highly specific Cas13 RNA-targeting in human cells

Research Interest: The Effect of U2 snRNA Pseudouridylation on Pre-mRNA Splicing in S. cerevisiae

Research Interest: Similarities and differences in tRNA quality control decay pathways in evolutionarily distant yeast species

Research Interest: Distinguishing the roles of TatSF1 and U2AF65 paralogues in HIV vs. host gene expression

Research Interest: The Role of DDX3X in the Translation of Cardiomyocyte Transcription Factors

Research Interest: Mechanisms Which Maintain the Reading Frame During Ribosome Stalls

Research Interest: Cracking the Function of PRRC2B in Translation Initiation

Research Interest: Exploring the use of suppressor tRNAs for suppression of nonsense mutations in the CFTR gene as a potential treatment for cystic fibrosis

Research Interest: Cancer-associated mutations of the pre-mRNA splicing factor U2AF2 alter splice site signal recognition

Research Interest: Identifying common features of piRNA precursors using computational and biophysical approaches

Research Interest: Structural Analysis of a Riboswitch Reveals Long-Range Interaction Spine Bridging Distant Domains

Research Interest: Hydrogen Bond Model Selection for RNA Force Fields

Research Interest: Structure and effector-binding analysis of a PreQ1-III riboswitch suggests a fold that is tolerant to binding pocket mutations

Research Interest: mRNA splicing is a marker of molecular pathology and disease severity in myotonic muscular dystrophy

Research Interest: Biology of 2'-O-methylation in the anticodon loop of yeast tRNAs

Research Interest: Evaluating the Potential of Tumor Suppressor p53 to Preserve Pancreatic Acinar Cell Identity

Research Interest: The Role of Csx28 in CRISPR-Cas13b Anti-Phage Defense

Research Interest: Lie Xi joined the Proschel Lab in 2016, and is currently applying his extensive molecular skill towards analyzing the effects of EIF2B mutations in VWM disease on astrocyte function. He also collaborates with the spinal cord research team on investigating the effects of new pharmacological treatments on the Immune response in acute SCI. Lie Xi also became a proud father this year!