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URMC / Center for AIDS Research


Center for AIDS Research

Improving the prevention, detection and treatment of HIV infection, AIDS and related diseases.

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To provide leadership, services and infrastructure necessary to: establish multidisciplinary collaborations that achieve high-impact discoveries; support the early career development of diverse young HIV/AIDS investigators; and to establish a distinctive scientific identity, placing the University of Rochester at the forefront of HIV/AIDS research.

Recent Publications

Hammond, JW, Lu, S-M and Gelbard, HA. (2016) Platelet activating factor enhances synaptic vesicle exocytosis via PKC, elevated intracellular calcium, and modulation of synapsin 1 dynamics and phosphorylation. Front. Cell. Neurosci. | doi: 10.3389/fncel.2015.00505.

Liu*, B., Qiu*, X., Zhu, T., Tian, W., Hu, R., Ekholm, S., Schifitto, G., Zhong, J. (2016) Spatial regression analysis of serial DTI for subject-specific longitudinal changes of neurodegenerative disease, NeuroImage : Clinical. 2016;11:291-301. doi:10.1016/j.nicl.2016.02.009

Shah, K., Yang, H., Luque, A.E., Hall,W.J., Dewhurst, S. (2016) Enhancing Physical Function In Hiv-Infected Older Adults: A Randomized Controlled Clinical Trial. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 2016;35(6):563-573. doi:10.1037/hea0000311.

Adler D, Wallace M, Bennie T, Abar B, Sadeghi R, Meiring M, Williamson A, Bekker L. (2015) High Risk HPV Persistence Among HIV-infected Young Women in South Africa. International Journal of Infectious Diseases. 33: e219-21.

Anderson AM, Harezlak J, Bharti A, Mi D, Taylor MJ, Daar ES, Schifitto G, Zhong J, Alger JR, Brown MS et al: (2015) Plasma and cerebrospinal fluid biomarkers predict cerebral injury in HIV-infected individuals on stable combination antiretroviral therapy.  Journal of acquired immune deficiency syndromes. 2015;69(1):29-35.

Blanchard C, Brooks L, Beckley A, Colquhoun J, Dewhurst S, Dunman PM. Neomycin Sulfate Improves the Antimicrobial Activity of Mupirocin-Based Antibacterial Ointments. Antimicrob Agents Chemother. 2015 Nov 23;60(2):862-72.

Huang H, Santoso  N, Power D, Simpson S, Dieringer M, Miao H, Gurova K, Giam CZ, Elledge SJ, Zhu J. (2015) FACT Proteins, SUPT16H and SSRP1, are Transcriptional Suppressors of Human Retroviruses (HIV-1/HTLV-1) that Facilitate Viral Latency. J Biol Chem. 290(45): 27297-310.

Johnson BA. (2015) “On Huberized calibration regression for censored medical cost data.” Statistics in Biosciences 7(2):367-378.

Kiebala M, Singh MV, Piepenbrink MS, Qiu X, Kobie JJ, Maggirwar SB. Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. PLoS One. 2015 Jun 15;10(6):e0130061.

Kobie, J.J., Zheng, B., Piepenbrink, M.S., Hessell A.J., Haigwood, N.L., Keefer, M.C., and Sanz, I.  (2015) Functional and molecular characterization of novel and conserved cross-clade HIV envelope specific human monoclonal antibodies.   Monoclon Antib Immunodiagn Immunother. Apr;34(2):65-72.

Lin M, He H, Schifitto G, Zhong J. (2015) Simulation of changes in diffusion related to different pathologies at cellular level after traumatic brain injury. Magn Reson Med. 2015. Epub 2015/08/11. doi: 10.1002/mrm.25816.

Liu, Z.P., Wu, C., Miao H., Wu, H. (2015). RegNetwork: an Integrated Database of Transcriptional and Posttranscriptional Regulatory Networks in Human and Mouse.

Power D, Santoso N, Dieringer M, Yu J, Huang H, Simpson S, Seth I, Miao H, Zhu J. (2015) IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency. Virology, 2015. 481: p. 142-50.  

Puccini, JM, Marker, DF, Fitzgerald, T, Barbieri, J, Kim, CS, Miller-Rhodes, P, Lu, S-M, Dewhurst, S and HA Gelbard.  (2015) LRRK2 Modulates Neuroinflammation and Neurotoxicity in Models of HIV-1 Associated Neurocognitive DisordersJ. Neurosci. 2015 Apr 1;35(13):5271-83. doi: 10.1523/JNEUROSCI.0650-14.2015. 

Shah K, Majeed Z, Yang H, Guido J, Polesskaya O, Hilton TN, Hall WJ, Luque AE. (2015) Functional Limitations and Adipokines in HIV-Infected Older Adults. J Frailty Aging, 4(1), 41–46.

Shah K, McMahon JM, Trabold N, Aidala AA, Chen M, Pouget ER, Simmons J, Klostermann K. (2015). Determinants of physical and global functioning in adult HIV-positive heterosexual men. AIDS Care, 27(9), 1079–1086.

Sheik DA, Brooks L, Frantzen K, Dewhurst S, Yang J. Inhibition of the enhancement of infection of human immunodeficiency virus by semen-derived enhancer of virus infection using amyloid-targeting polymeric nanoparticles. ACS  Nano. 2015 Feb 24;9(2):1829-36.

Singh, V. B., Wooten, A. K., Jackson, J. W., Maggirwar, S. B., Kiebala, M. (2015). Investigating the role of ankyrin-rich membrane spanning protein in human immunodeficiency virus type-1 Tat-induced microglia activation. J Neurovirol. 2015 Apr;21(2):186-98. doi: 10.1007/s13365-015-0318-2. Epub 2015 Jan 31.

Stephenson R, Finneran, C, Goldenberg, T, Coury-Doniger, P, Senn, T,  Urban, M, Schwartz, A, Sullivan, P. (2015). Willingness to use couples HIV testing and discussion of sexual agreements among heterosexuals. SpringerPlus, 4, 169.

Tivarus ME, Pester B, Schmidt C, Lehmann T, Zhu T, Zhong J, Leistritz L, Schifitto G. (2015) Are structural changes Induced by lithium in the HIV Brain accompanied by changes in functional connectivity? PLoS One. 2015 Oct 5;10(10):e0139118. doi: 10.1371/journal.pone.0139118. eCollection 2015.

Zhang, G, Guo, D, Dash, P, Arainga, M, Wiederin, JL, Haverland, NA, Knibbe-Hollinger, J, Martinez-Skinner, A, Ciborowski, P, Goodfellow, VS, Wysocki, TA, Wyosocki, BJ, Poluektova, LY, Liu, X-M, McMillan, JM, Gorantla, S, Gelbard, HA  and Gendelman, HE. (2015) The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-Acting Antiretroviral Therapy.  Nanomedicine. 2015 Oct 12. pii: S1549-9634(15)00187-2. doi: 10.1016/j.nano.2015.09.009. [Epub ahead of print]; selected for cover of January 2016