Regulation of macrophage function in innate immunity
Differentiation of CD4 T lymphocytes in infectious and autoimmune disease
Dynamic regulation of leukocyte adhesion and migration
Innate immunity in influenza infection, Regulation of immune responses via trail formation
Understanding mechanisms for generating and maintaining T cell memory, with particular emphasis on responses primed by immunization with dendritic cells
Molecular and cellular events that regulate T cell signaling and activation
The regulation of cytokine responses of human and mouse T-cell subsets in infections asthma, allergy and autoimmunity
Standardization of immunological techniques for clinical investigation of human immune status.
B cell responses to influenza infection and vaccination; B cell memory; mucosal immunology; mathematical modeling of B cell responses
Influenza specific immunity, vaccine design and regulation of T cell responses to pathogens.
Conducting clinical and translational research on respiratory pathogens, immunity, and infectious disease, including the study of environmental factors that affect immune responses to influenza and vaccination, seeking new approaches to enhance immunity, reduce pathology, and prevent disease.
Innate immunity, Host-microbial interactions, Immunoparasitology, Mucosal immunology