Research Labs

Our faculty, staff and students work as a team to create an atmosphere of learning, growing and life-long friendships. If you are interested in joining our team, please feel free to contact us for more information.

Charles J. Lowenstein , M.D.

Dr. Charles LowensteinDr. Lowenstein's research is focused on vascular biology. One team of researchers explores mechanisms of exocytosis, through which endothelial cells release pro-inflammatory and pro-thrombotic mediators. A second group of scientists study how platelets communicate with endothelial cells. A third area of research involves an exploration of the role of microRNA in endothelial cells. A fourth team investigates how nitric oxide affects vascular inflammation. View Lowenstein Lab page

Bradford C. Berk, M.D., Ph.D.

Bradford BerkDr. Berk's laboratory is focused on defining the mechanisms by which cells in the vascular wall respond to hemodynamic and hormonal stimuli. View Berk Lab page

Zheng-Gen Jin, Ph.D.

Zheng-Gen JinDr. Jin’s research has been focused on molecular regulation of vascular endothelial function. Vascular endothelial cells in blood vessels produce a number of vasodilator and vasoconstrictor substances that not only physiologically regulate vasomotor tone and vascular homeostasis, but also mediate the recruitment and activity of inflammatory cells and the propensity towards atherosclerotic lesion
formation and thrombosis in the pathological condition. View Jin Lab page

Slava Korshunov , Ph.D.

Slava KorshunovDr. Korshunov's major focus is the understanding of mechanisms that regulate the structure of blood vessels (a process we call “vascular remodeling”) could prevent cardiovascular morbidity and mortality in humans.
View Korshunov Lab page


Coeli Lopes, Ph.D.

Coeli LopesThe major focus of Dr. Lopes current work involves the regulation of the slow delayed rectifier-like current (IKs) in the heart and the pathogenesis of the Long QT (LQT1) syndrome. View Lopes Lab page

Joseph Miano, Ph.D.

Joseph MianoMy lab utilizes state-of-the-art methods in molecular biology, genetics, genomics, and computational biology to acquire in-depth knowledge on the transcriptional regulation of gene expression and the functional role of regulatory proteins in Alzheimer’s disease and vascular occlusive disease.

View Miano Lab page

Craig Morrell, DVM, Ph.D.

Craig MorrellPlatelets have two major functions: hemostastis/thrombosis and an immune regulatory function. My laboratory uses in vitro techniques and in vivo mouse models to study both important platelet functions.
View Morrell Lab page

Jinjiang Pang, B.Med., Ph.D.

Jinjiang PangAngiogenesis, the formation of new blood vessels from existing ones, is a critical event for tissue development and repair, as well as being associated with many diseases (e.g. bronchopulmonary dysplasia, pulmonary artery hypertension, ischemic cardiomyopathy, retinopathy and tumor growth).

View Pang Lab page

Eric Small, Ph.D.

Eric SmallResearch in the Small Lab is focused on understanding the molecular mechanisms that control how a cell responds to its surroundings during development or following tissue injury.
View Small Lab page

Jane Sottile, Ph.D.

Jane SottileRemodelling of extracellular matrices occurs during development, wound healing, and in a variety of pathological processes including atherosclerosis, ischemic injury, and angiogenesis. Perturbing matrix remodelling events by preventing the turnover of extracellular matrix molecules, or by increasing the levels of matrix degrading proteases or inhibitors has been shown to result in fibrosis, arthritis, reduced angiogenesis, and developmental abnormalities.

View Sottile Lab page

Chen Yan, Ph.D.

Chen YanRegulation and function of cyclic nucleotide phosphodiesterases in the cardiovascular system. Second messenger cyclic nucleotides (cAMP and cGMP) regulate many signaling pathways in the cardiovascular system.

View Yan Lab page

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