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EHSC People

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Danielle Benoit, Ph.D.Danielle Benoit, Ph.D.
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Biomedical Engineering
Benoit Lab

Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments
Deborah Cory-Slechta, Ph.D.Deborah Cory-Slechta, Ph.D.
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Environmental Medicine
Cory-Slechta Lab

Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.
Daniel Croft, M.D., M.P.H.Daniel Croft, M.D., M.P.H.
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Medicine

Health effects of air pollution, with a current focus on the contribution of air pollution to individuals suffering from respiratory viral infections
Lisa DeLouise, Ph.D., M.P.D.Lisa A. DeLouise, Ph.D., M.P.D.
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Dermatology
DeLouise Lab

Understanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.
Alison Elder, Ph.D.Alison Elder, Ph.D.
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Environmental Medicine
Elder Lab

Defining the impact of inhaled ambient and workplace nano-/ultrafine particle-containing aerosols on the lung, cardiovascular system, and central nervous system, and defining the toxicological properties of the particles that are associated with a response.
Jacob Finkelstein, Ph.D.Jacob N. Finkelstein, Ph.D.
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Pediatrics
Finkelstein Lab

Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.
Dragony Fu, Ph.D.Dragony Fu, Ph.D.
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Biology
Fu Lab

Nucleic acid modification and repair mechanisms linked to neurodevelopmental disorders, mitochondrial diseases, and cancer.
Steve Georas, M.D.Steve Georas, M.D.
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Medicine
Georas Lab

Defining the role of environmental exposures on innate and adaptive immunity in asthma and other chronic lung diseases, with an emphasis on how particulate matter and endocrine disruptors act as risk factors.
Elaine Hill, Ph.D.Elaine Hill, Ph.D.
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Public Health Sciences
Hill Lab

Early origins research, linking in utero environment to later life health and educational attainment
Todd Jusko, Ph.D.Todd A. Jusko, Ph.D.
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Public Health Sciences
Rochester Environment and Child Health (REACH) Laboratory

Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.
Kirsi Järvinen-Seppo, M.D., Ph.D.Kirsi M. Järvinen-Seppo, M.D., Ph.D.
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Pediatrics
Järvinen-Seppo Lab

Food allergies disorders, caused by milk, eggs and peanuts.
Katrina Korfmacher, Ph.D.Katrina Korfmacher, Ph.D.
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Environmental Medicine

Community outreach and engagement, role of science in public decision-making
B. Paige Lawrence, Ph.D.B. Paige Lawrence, Ph.D.
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Environmental Medicine
Lawrence Lab

Delineating mechanisms by which environmental exposures during different life stages alter immune function; discovering how environmental factors modulate epigenetic programming of the developing immune system, and the consequences of these changes on susceptibility to infectious, allergic, or autoimmune disease later in life.
Xin Li, Ph.D.Xin Zhiguo Li, Ph.D.
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Biochemistry & Biophysics
Li Lab

Our research is to define the RNA functions in reproduction and transgenerational epigenetic inheritance.
Augusto Litonjua, M.D., M.P.H.Augusto A. Litonjua, M.D., M.P.H.
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Medicine
Pediatrics

Investigating factors that both increase and decrease the risk of developing asthma, wheezing, and allergic disorders in childhood
Tanzy Love, Ph.D.Tanzy Love, Ph.D.
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Biostatistics & Computational Biology

Finding hidden groups and their meanings; latent variable modeling; methods and techniques for Bayesian solutions.
Thomas Mariani, Ph.D.Thomas Mariani, Ph.D.
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Pediatrics
Mariani Lab

Systems Biology of Lung Development and Disease
Margot Mayer-Pröschel, Ph.D.Margot Mayer-Pröschel, Ph.D.
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Biomedical Genetics
Mayer-Pröschel Lab

Deciphering the impact of nutritional, toxicological, viral, and genetic insults, singly and in combination, on mammalian brain development and disease later in life.
Matthew McCall, Ph.D.Matthew McCall, Ph.D.
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Biostatistics & Computational Biology

Developing methods to estimate gene regulatory networks from gene pertubation experiments
Matthew McGraw, M.D.Matthew McGraw, M.D.
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Pediatrics

Understanding the mechanisms of aberrant airway epithelial repair after inhalation injuries
Gary Myers, M.D.Gary J. Myers, M.D.
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Neurology

Environmental toxins, specifically mercury; methyl mercury exposure
Mark Noble, Ph.D.Mark Noble, Ph.D.
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Biomedical Genetics
Noble Lab

Discovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.
M. Kerry O'Banion, M.D., Ph.D.M. Kerry O'Banion, M.D., Ph.D.
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Neuroscience
O'Banion-Olschowka Labs

Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure
Thomas O'Connor, Ph.D.Thomas O'Connor, Ph.D.
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The mechanisms by which early stress exposures, including prenatal maternal anxiety and caregiving stress, may persistently shape children's behavioral and biological health
Michael O'Reilly, Ph.D.Michael A. O'Reilly, Ph.D.
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Pediatrics
O'Reilly Lab

Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.
David Oakes, Ph.D.David Oakes, Ph.D.
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Biostatistics & Computational Biology

Univariate and multiivariate survival analysis and in the analysis of multiple event-time data
Günter Oberdörster, D.V.M., Ph.D.Günter Oberdörster, D.V.M., Ph.D.
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Environmental Medicine
Elder Lab

Biokinetics, Effects and Mechanisms of Inhaled Micro- and Nano- Particles: Dosimetry, Risk Extrapolation and Risk Assessment
Gloria Pryhuber, M.D.Gloria S. Pryhuber, M.D.
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Pediatrics
Pryhuber Lab

Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.
J. Edward Puzas, Ph.D.J. Edward Puzas, Ph.D.
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Orthopaedics
Puzas Lab

Deciphering the molecular signals that govern osteoporosis and arthritis, as well as cellular changes that contribute to difficulties such as the loosening of artificial joints, including defining how environmental toxins such as lead, play a role in bone and joint diseases.
Arshad Rahman, Ph.D.Arshad Rahman, Ph.D.
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Pediatrics
Arshad Rahman Lab

Determining how exogenous agents change lung microvasculature permeability, leading to pulmonary inflammation.
Irfan Rahman, Ph.D.Irfan Rahman, Ph.D.
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Environmental Medicine
Irfan Rahman Lab

Defining effects of inhaled environmental tobacco smoke, e-cigarettes, flavoring chemicals, and water pipe smoke toxicants on mitochondrial function, exosomes, and epigenetic chromatin modifiers in lung cell senescence, oxidative stress, and inflammation.
Matthew Rand, Ph.D.Matthew D. Rand, Ph.D.
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Environmental Medicine
Rand Lab

Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.
David Rich, Sc.D., M.P.H.David Rich, Sc.D., M.P.H.
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Public Health Sciences
Rich Lab

Examining associations between air pollution and cardiopulmonary and pregnancy outcomes, validating biomarkers that may explain associations and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposures.
Jacques Robert, Ph.D.Jacques Robert, Ph.D.
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Microbiology & Immunology
Robert Lab

Using a comparative biology approach to advance immunotoxicology, leveraging the amphibian Xenopus and the pox-like ranavirus FV3, to address long-term effects of water pollutants on immune cell development and on antiviral immunity across the lifespan.
Patricia Sime, M.D.Patricia Sime, M.D.
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Medicine
Sime Lab

Conducting clinical and translational toxicology research focusing on the lung, from studies of silica and radiation in lung fibrosis, to the effects of biomass and cigarette smoke exposure on lung inflammation and resolution pathways, to identifying key pathophysiologic pathways and developing novel therapeutics for lung inflammation and fibrosis.
Marissa Sobolewski, Ph.D.Marissa Sobolewski, Ph.D.
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Environmental Medicine
Sobolewski Lab

Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.
Martha Susiarjo, Ph.D.Martha Susiarjo, Ph.D.
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Environmental Medicine
Susiarjo Lab

Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.
Sally Thurston, Ph.D.Sally Thurston, Ph.D.
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Biostatistics & Computational Biology

Bayesian inference, modeling multiple outcomes, correction for measurement error bias, informative prior specification, latent variable models, and environmental health applications.
David Topham, Ph.D.David Topham, Ph.D.
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Microbiology & Immunology
Topham Lab
Program for Advanced Immune Bioimaging

Conducting clinical and translational research on respiratory pathogens, immunity, and infectious disease, including the study of environmental factors that affect immune responses to influenza and vaccination, seeking new approaches to enhance immunity, reduce pathology, and prevent disease.
Edwin Van Wijngaarden, Ph.D., M.Sc.Edwin Van Wijngaarden, Ph.D., M.Sc.
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Epidemiology
Public Health Sciences
VanWijngaarden Lab

Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.
Jacqueline Williams, Ph.D.Jacqueline Patricia Williams, Ph.D.
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Environmental Medicine
Jacqueline Williams Lab

Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.
Hugh Xia, M.Sc., Ph.D.Hugh Houhui Xia, M.Sc., Ph.D.
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Pharmacology & Physiology
Xia Lab

Investigating the role of environmental toxins such as arsenic on the protein phosphatase-1, a regulator of synaptic plasticity and cognition.
Wojciech Zareba, M.D., Ph.D.Wojciech Zareba, M.D., Ph.D.
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Medicine

Risk stratification of cardiac death and on clinical usefulness and prognostic significance of ECG parameters