Effects of particle exposure on lung function, airway inflammation, and cardiovascular function.
The role of the alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli.
Regulation of airway immune responses by respiratory viruses, allergens, and pollutants
How environmental chemicals contribute to adverse immunological development over the entire lifespan.
Neurodegenerative diseases affecting the basal ganglia, particularly Parkinson disease, Huntington disease, and HIV related neurologic disorders
Translational Research in Autoimmune Disease, B Cell Depletion
Reproductive and perinatal toxicology, Normal development of the embryo/fetus
Systems Biology of Lung Development and Disease
Environmental toxins, specifically mercury; methyl mercury exposure
Developmental Biology of the Lung
Molecular and Cellular Biology of the Skeletal System
The Pryhuber lab is currently focused on three NIH funded studies, the Prematurity and Respiratory Outcomes Program, the Respiratory Pathogens Research Center study of longitudinal respiratory and gut microbiome development, lymphocyte maturity, viral infections and respiratory outcomes at 3 years of age in preterm and full term infants, and most recently, providing the Human Tissue Core for the Lung Molecular Atlas Program.
Modulation of Pulmonary Inflammation using Gene Transfer Techniques
Occupational and environmental epidemiology, cancer epidemiology