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Faculty

Primary Faculty

Deborah Cory-Slechta
Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.
Alison Elder
Defining the impact of inhaled ambient and workplace nano-/ultrafine particle-containing aerosols on the lung, cardiovascular system, and central nervous system, and defining the toxicological properties of the particles that are associated with a response.
Susan Holt
Lead curriculum writer for all Life Sciences Learning Center ‘classroom based’ science lessons and student assessment.
Katrina Korfmacher
Community outreach and engagement, role of science in public decision-making
B. Paige Lawrence
Delineating mechanisms by which environmental exposures during different life stages alter immune function; discovering how environmental factors modulate epigenetic programming of the developing immune system, and the consequences of these changes on susceptibility to infectious, allergic, or autoimmune disease later in life.
Richard Phipps
Investigating how environmental factors shape diseases involving immune and inflammatory components, including platelets, B cells, and lipid mediators, defining abnormal inflammatory and wound healing responses in the eye and lung, delineating molecular signaling in fibroblasts.
Irfan Rahman
Defining effects of inhaled environmental tobacco smoke, e-cigarettes, flavoring chemicals, and water pipe smoke toxicants on mitochondrial function, exosomes, and epigenetic chromatin modifiers in lung cell senescence, oxidative stress, and inflammation.
Matthew Rand
Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.
Martha Susiarjo
Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.
Marissa Terry
Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.
Jacqueline Williams
Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.

Adjunct Faculty

Stephen Dertinger

Stephen Dertinger, Ph.D.


Research Faculty

Ravi Misra
Understanding mechanisms of pathology in common inflammatory conditions of children
Isaac Sundar
Circadian disruption, Cigarette smoke-induced chromatin modifications, cellular senescence and DNA damage/repair

Secondary Faculty

Jacob Finkelstein
Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.
Mark Frampton
Effects of particle exposure on lung function, airway inflammation, and cardiovascular function.
Steve Georas
Defining the role of environmental exposures on innate and adaptive immunity in asthma and other chronic lung diseases, with an emphasis on how particulate matter and endocrine disruptors act as risk factors.
Todd Jusko
Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.
R. John Looney
Translational Research in Autoimmune Disease, B Cell Depletion
Thomas Mariani
Systems Biology of Lung Development and Disease
Richard Miller
Determining the impact of maternal stress and other maternal factors on the birth outcomes and in the children.
Gary Myers
Environmental toxins, specifically mercury; methyl mercury exposure
Michael O'Reilly
Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.
Gloria Pryhuber
Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.
J. Edward Puzas
Deciphering the molecular signals that govern osteoporosis and arthritis, as well as cellular changes that contribute to difficulties such as the loosening of artificial joints, including defining how environmental toxins such as lead, play a role in bone and joint diseases.
David Rich
Examining associations between air pollution and cardiopulmonary and pregnancy outcomes, validating biomarkers that may explain associations and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposures.
Patricia Sime
Conducting clinical and translational toxicology research focusing on the lung, from studies of silica and radiation in lung fibrosis, to the effects of biomass and cigarette smoke exposure on lung inflammation and resolution pathways, to identifying key pathophysiologic pathways and developing novel therapeutics for lung inflammation and fibrosis.
Edwin Van Wijngaarden
Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.

Emeritus Faculty

Thomas Clarkson
Understanding the toxicities, mechanisms of action, and dose-reponse relationship for methyl mercury and other heavy metals.
Günter Oberdörster
Biokinetics, Effects and Mechanisms of Inhaled Micro- and Nano- Particles: Dosimetry, Risk Extrapolation and Risk Assessment