Welcome to the Thakar Lab
Immune response to infections, vaccination and environmental exposures depends on several factors including age, immunogenicity of the antigens, host genotype and host’s immune history.
The research focus of our lab is to delineate the effects of these factors using bioinformatics, systems biology, and dynamic modeling tools. We typically integrate different datasets including gene expression, metabolomics, single-cell RNA seq, proteomics, serum cytokine levels and known information about signaling and metabolic pathways. Recently, we are also working with adaptive immune receptor repertoire sequencing.