Honors & News
August 30, 2012
NIH Awards $7.5M, Designates URMC Orthopaedics as Center of Research Translation
The University of Rochester Medical Center was granted a $7.5 million Center of Research Translation (CORT) award for programs designed to find new therapies for arthritis and bone healing. With a rising population of older adults, musculoskeletal diseases are a major economic burden in the United States and in the health-care system, and the award places the URMC in a leadership role for seeking solutions.
Regis O'Keefe, M.D., Ph.D., the Marjorie Strong Wehle Professor in Orthopaedics and department chair, is the principal investigator. He noted that the unique structure of CORT requires collaboration among scientists, and rewards institutions that build on previous work in a highly integrated environment.
One of the three key initiatives of the CORT grant is Translating how PTH therapy can improve the healing of major bone defects caused by trauma. Led by Edward M. Schwarz, Ph.D., the Burton Professor of Orthopaedics and director of the URMC Center for Musculoskeletal Research, investigators are studying the role of PTH in preventing the body's negative reaction to reconstructive surgery following trauma or cancer.
April 17, 2012
Serious, drug-resistant staph infections are a growing problem in health care in the United States and across the globe. In a coordinated effort to stop these superbugs, investigators from the University of Rochester Medical Center have been selected to lead an ambitious, five-year project, with an emphasis on infections from complex orthopedic surgeries such as joint replacement, fracture repair, or trauma.
AOTrauma, part of the Switzerland-based AO Foundation, awarded $3 million to a team led by Stephen l. Kates, M.D., professor of Orthopaedics at URMC. The URMC has been studying ways to combat Methicillin-Resistant Staphylococcus Aureus (MRSA) for several years. Edward M. Schwarz, Ph.D., a co-investigator on the AOTrauma project, the Burton Professor of Orthopaedics, and director of the URMC Center for Musculoskeletal Research, is leading the development of a vaccine to prevent MRSA infections following bone and joint surgery.
- Increased numbers of CD23(+) CD21(hi) Bin-like B cells in human reactive and rheumatoid arthritis lymph nodes.Eur J Immunol. 46, 1752-7. (2016 Jul 01).
- 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery.Ann Biomed Eng. (2016 Jun 20).
- Antioxidant impregnated ultra-high molecular weight polyethylene wear debris particles display increased bone remodeling and a superior osteogenic:osteolytic profile vs. conventional UHMWPE particles in a murine calvaria model.J Orthop Res. 34, 845-51. (2016 May 01).