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Genomics & Bioinformatics

Xin Bi, Ph.D.Xin Bi, Ph.D.

Email XinBi

Bi Lab


Research Interest: 
Chromatin-mediated regulation of gene expression in eukaryotes.


Michael Bulger, Ph.D.Michael Bulger, Ph.D.

  | Associate Professor, Pediatrics

Research Interest:
Chromatin domains and long-range activation by enhancers.


Karl Glastad, Ph.D. Karl Glastad, Ph.D. 

 | Lab Website

Assistant Professor

Research Interest: Plasticity of aging, stress response, and metabolism. Also behavioral plasticity, why not?


Jeffrey J. Hayes, Ph.D.Jeffrey J. Hayes, Ph.D.

  | Visit Lab Website

Professor - Department of Biochemistry and Biophysics (SMD)

Chair - Department of Biochemistry and Biophysics (SMD)

Shohei Koide Professor in Biochemistry and Biophysics - Department of Biochemistry and Biophysics (SMD)

Research Interest: Regulation of transcription, nuclear processes, related to chromatin structure and function.


Hartmut Land, Ph.D.Hartmut Land, Ph.D.

  | Professor & Chair, Biomedical Genetics

Research Interest:
Molecular mechanisms of carcinogenesis and cancer cell metabolism.


Richard Libby, Ph.D.Hongbo Liu, Ph.D.

  | Assistant Professor, Department of Biomedical Genetics (SMD)

Research Interest:
Functional genome of aging and age-related diseases, with specific focus on human genetic variation, epigenome, and 3D genome, by leveraging the power of large-scale biobanks, single-cell multi-omics technologies, machine-learning/AI models and molecular experiments.


Thomas Mariani, Ph.D.Thomas Mariani, Ph.D.

  | Associate Professor, Pediatrics

Research Interest:
Systems Biology of Lung Development and Disease.


David Mathews, M.D., Ph.D.David Mathews, M.D., Ph.D.

  | Associate Professor, Biochemistry & Biophysics

Research Interest:
Computational biology and genomics of RNA.


Marlies P. Rossmann, M.D., Ph.D. Marlies P. Rossmann, M.D., Ph.D. 

Research Interest: Elucidate the metabolic origins of a variety of diseases, facilitate novel metabolism-centered differentiation therapies for hematological malignancies, and combat the decline in lymphoid cell production by the aging hematopoietic system.




Gabriella R. Sterne, Ph.D.Gabriella R. Sterne, Ph.D.

 | Lab website

Associate Professor, Department of Biomedical Genetics



Stephano Spano Mello, Ph.D.Stephano Spano Mello, Ph.D.

  | Visit Lab Website

Assistant Professor, Department of Biomedical Genetics

Research Interest:
Understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation.


Alexander Paciorkowski, M.D.Alexander Paciorkowski, M.D.

  | Assistant Professor, Neurology

Research Interests:
Pediatric Neurology, Human Genetics.



Peng Yao, Ph.D.Peng Yao, Ph.D.

  | Lab website

Associate Professor, Department of Medicine , Department of Biochemistry and Biophysics

Research Interest:
Pathophysiological function and molecular mechanism of new non-coding RNAs (and RBPs) and new modes of gene regulation in cardiac system and cardiovascular disease.


Douglas Stuart Portman, Ph.D.Douglas Stuart Portman, Ph.D.

  | Professor, Department of Biomedical Genetics (SMD), Department of Biology RC (RC)Department of Neuroscience

Research Interests: 
Neural circuit development and function; Genetic control of behavior; Sex differences in neurobiology.


Laurie A. Steiner, M.D.Laurie A. Steiner, M.D.

 | Visit Steiner Lab

Associate Professor - Department of Pediatrics , Neonatology (SMD)

Research Interest:
Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.


Paula M. Vertino, Ph.D.Paula M. Vertino, Ph.D.

| Professor - Department of Biomedical Genetics (SMD)

  • Wilmot Distinguished Professorship in Cancer Genomics - Cancer Center

Professor - Department of Pathology and Laboratory Medicine (SMD)

Research Interest:
Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic intervention.