Education / Graduate Education / PhD Programs / Biomedical Genetics and Genomics / Faculty & Students / Faculty Faculty Aging & Stress Cancer Biology Cell & Developmental Biology Disease Models Genomics & Bioinformatics Neurobiology RNA Biology ABCDEFGHIJKLMNOPQRSTUVWXYZAffiliated FacultyKate Ackerman, M.D.Email KateAckermanBiomedical GeneticsPediatricsResearch Interest: Genetics of Congenital Diaphragmatic Hernia in lung development Brian Altman, Ph.D.Email BrianAltmanAltman LabBiomedical GeneticsResearch Interest: Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism. Douglas Anderson, Ph.D.Email DouglasAndersonAnderson LabMedicinePharmacology & PhysiologyResearch Interest: LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.Jeevisha Bajaj, Ph.D.Email JeevishaBajajBajaj LabBiomedical GeneticsResearch Interest: Molecular mechanisms of cancer stem cell interactions with tumor microenvironment in disease progressionDanielle Benoit, Ph.D.Email DanielleBenoitBenoit LabChemical EngineeringBiomedical EngineeringResearch Interest: Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments Daniel Bergstralh, Ph.D.Email DanielBergstralhBergstralh LabBiologyBiomedical GeneticsResearch Interest: Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.Bradford Berk, M.D., Ph.D.Email BradfordBerkBerk LabMedicinePharmacology & PhysiologyNeurologyResearch Interest: Signaling transduction mechanisms in the vascular system Xin Bi, Ph.D.Email XinBiBi LabBiologyResearch Interest: Chromatin-mediated regulation of gene expression in eukaryotes.Benoit Biteau, Ph.D.Email BenoitBiteauBiteau LabBiomedical GeneticsResearch Interest: Molecular and Cellular Mechanisms that Control Tissue Homeostasis and Somatic Stem CellsDirk Bohmann, Ph.D.Email DirkBohmannBohmann LabBiomedical GeneticsResearch Interest: The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and diseasePaul Boutz, Ph.D.Email PaulBoutzBoutz LabBiochemistry & BiophysicsResearch Interest: Regulation of pre-mRNA splicing and polyadenylation in healthy and diseased states; the contribution of RNA processing to cancer biology; effects of small molecule drugs on RNA processing and gene expression.Michael Bulger, Ph.D.Email MichaelBulgerBulger LabPediatricsBiochemistry & BiophysicsResearch Interest: Chromatin domains and long-range activation by enhancersStephen Dewhurst, Ph.D.Email StephenDewhurstDewhurst LabMicrobiology & ImmunologyMark Dumont, Ph.D.Email MarkDumontDumont LabPediatricsBiochemistry & BiophysicsResearch Interest: Signal transduction; membrane protein structure, yeast molecular biologyThomas Eickbush, Ph.D.Email ThomasEickbushEickbush LabBiologyResearch Interest: Retrotransposable elements, protein: RNA and protein: DNA interactions, sequence specific endonucleases.Dmitri Ermolenko, Ph.D.Email DmitriErmolenkoErmolenko LabBiologyBiochemistry & BiophysicsResearch Interest: Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.Robert Freeman, Ph.D.Email RobertFreemanFreeman LabPharmacology & PhysiologyResearch Interest: Molecular biology of programmed cell deathElizabeth Grayhack, Ph.D.Email ElizabethGrayhackGrayhack LabBiochemistry & BiophysicsResearch Interest: Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.Isaac Harris, Ph.D.Email IsaacHarrisHarris LabBiomedical GeneticsResearch Interest: Understanding the roles of antioxidants in diseaseJeffrey Hayes, Ph.D.Email JeffreyHayesWilliam A. Bernhard Memorial LabHayes LabBiochemistry & BiophysicsResearch Interest: Regulation of transcription, nuclear processes, related to chromatin structure and function Aram Hezel, M.D.Email AramHezelBiomedical GeneticsMedicineResearch Interest: The molecular biology and genetics of pancreatic and biliary tract cancers Amy Kiernan, Ph.D.Email AmyKiernanKiernan LabOphthalmologyFlaum Eye InstituteBiomedical GeneticsResearch Interest: Molecular development of the eye and inner ear; anterior segment dysgenesis (ASD) and developmental glaucoma; congenital deafness and vestibular dysfunction Hartmut Land, Ph.D.Email HartmutLandLand LabBiochemistry & BiophysicsBiomedical GeneticsResearch Interest: Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell MetabolismAmanda Larracuente, Ph.D.Email AmandaLarracuenteLarracuente LabBiologyResearch Interest: Satellite DNA (repetitive DNA typically found at centromeres and telomeres), Meiotic Drive, and Selfish DNA using genomic, population genetic, molecular and cytological methods.Xin Li, Ph.D.Email XinLiLi LabBiochemistry & BiophysicsResearch Interest: Epigenetic inheritance, small silencing non-coding RNAs, translational control, lead toxicity, and comparative genomics.Richard Libby, Ph.D.Email RichardLibbyLibby LabBiomedical GeneticsFlaum Eye InstituteOphthalmologyResearch Interest: Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death. Alayna Loiselle, Ph.D.Email AlaynaLoiselleLoiselle LabOrthopaedicsResearch Interest: Musculoskeletal tissue regenerationLynne Maquat, Ph.D.Email LynneMaquatMaquat LabBiochemistry & BiophysicsResearch Interest: RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.Thomas Mariani, Ph.D.Email ThomasMarianiMariani LabBiomedical GeneticsMedicineEnvironmental MedicinePediatricsResearch Interest: Genetic mechanisms of susceptibility to congenital and infectious lung diseases, focusing on developmental antecedents and the influence of environmental factors. David Mathews, M.D., Ph.D.Email DavidMathewsMathews LabBiochemistry & BiophysicsResearch Interest: Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.Margot Mayer-Pröschel, Ph.D.Email MargotMayer-PröschelMayer-Pröschel LabNeuroscienceBiomedical GeneticsResearch Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies. Matthew McCall, Ph.D.Email MatthewMcCallBiomedical GeneticsBiostatistics & Computational BiologyResearch Interest: Developing methods to estimate gene regulatory networks from gene perturbation experimentsHelene McMurray, Ph.D.Email HeleneMcMurrayMcMurray LabPathology & Laboratory MedicineResearch Interest: Analysis of gene regulatory networks in cancer; role of immunogenetics in transplant Stephano Mello, Ph.D.Email StephanoMelloMello LabBiomedical GeneticsResearch Interest: Understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation.Edward Messing, M.D.Email EdwardMessingPathology & Laboratory MedicineUrologyResearch Interest: Prostate and Bladder cancer Patrick Murphy, Ph.D.Email PatrickMurphyPatrick Murphy LabBiomedical GeneticsResearch Interest: The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.Keith Nehrke, Ph.D.Email KeithNehrkeNehrke LabPharmacology & PhysiologyMedicineResearch Interest: Integrative PhysiologyMark Noble, Ph.D.Email MarkNobleNoble LabBiomedical GeneticsNeuroscienceResearch Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury. Mitchell O'Connell, Ph.D.Email MitchellO'ConnellO'Connell LabBiochemistry & BiophysicsResearch Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool developmentMichael O'Reilly, Ph.D.Email MichaelO'ReillyO'Reilly LabPediatricsEnvironmental MedicineResearch Interest: Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.Catherine Ovitt, Ph.D.Email CatherineOvittOvitt LabBiomedical GeneticsResearch Interest: Protective and regenerative strategies for salivary gland function and radiation therapies.Alexander Paciorkowski, M.D.Email AlexanderPaciorkowskiPaciorkowski LabNeuroscienceBiomedical GeneticsNeurologyPediatricsResearch Interest: Pediatric Neurology, Human GeneticsJames Palis, M.D.Email JamesPalisPalis LabBiomedical GeneticsPediatricsResearch Interest: Cellular and Molecular events underlying the ontogeny of the hematopoietic system. Archibald Perkins, M.D., Ph.D.Email ArchibaldPerkinsPerkins / Zhang LabPathology & Laboratory MedicineResearch Interest: Genetic mechanisms in acute myeloid leukemia and myelodysplastic syndrome with focus on the zinc finger oncoprotein EVI1 Eric Phizicky, Ph.D.Email EricPhizickyPhizicky LabBiochemistry & BiophysicsResearch Interest: tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.Douglas Portman, Ph.D.Email DouglasPortmanPortman LabNeuroscienceBiomedical GeneticsBiologyResearch Interest: Neural circuit development and function; Genetic control of behavior; Sex differences in neurobiologyChristoph Pröschel, Ph.D.Email ChristophPröschelPröschel LabBiomedical GeneticsResearch Interest: Astrocyte development in normal and pathological conditions, role of astrocytes in modulating response to injury or stress, utility of glial precursor cells and their astrocytic progeny for cell transplantation therapyJacques Robert, Ph.D.Email JacquesRobertRobert LabMicrobiology & ImmunologyEnvironmental MedicineResearch Interest: Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunologyRegina Rowe, M.D., Ph.D.Email ReginaRoweRowe LabPediatricsResearch Interest: Mechanisms of how allergic inflammation impacts innate immune cell antiviral responses. Andrew Samuelson, Ph.D.Email AndrewSamuelsonSamuelson LabBiomedical GeneticsResearch Interest: Understanding the genetic, cell biological and molecular basis for age-driven proteostatic deteriorationEdward Schwarz, Ph.D.Email EdwardSchwarzSchwarz LabPathology & Laboratory MedicineUrologyMedicineBiomedical EngineeringMicrobiology & ImmunologyOrthopaedicsResearch Interest: Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants Ruchira Singh, Ph.D.Email RuchiraSinghSingh LabFlaum Eye InstituteBiomedical GeneticsOphthalmologyResearch Interest: Using patient-derived human induced pluripotent stem cells (hiPSCs) to study the molecular mechanism of specific retinal and neurological diseases and applying that knowledge to pharmacologically target certain retinal disorders in patient-derived cells. Marissa Sobolewski-Terry, Ph.D.Email MarissaSobolewski-TerrySobolewski LabEnvironmental MedicineResearch Interest: Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.Laurie Steiner, M.D.Email LaurieSteinerSteiner LabPediatricsMedicineResearch Interest: Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.Martha Susiarjo, Ph.D.Email MarthaSusiarjoSusiarjo LabEnvironmental MedicineResearch Interest: Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.Michael Telias, Ph.D.Email MichaelTeliasTelias LabOphthalmologyFlaum Eye InstituteNeuroscienceResearch Interest: Retinal degeneration and maladaptive plasticity in inner retinal circuits.Marissa Terry, Ph.D.Email MarissaTerryJuilee Thakar, Ph.D.Email JuileeThakarThakar LabProgram for Advanced Immune Bioimaging Microbiology & ImmunologyResearch Interest: Systems approach utilizing bioinformatics, and dynamic modeling tools to study immune response to infections and vaccination. Charles Thornton, M.D.Email CharlesThorntonThornton LabNeurologyNeuroscienceResearch Interest: Myotonic dystrophy, repeat expansion diseases, and therapeutic development for neuromuscular disorders.Paula Vertino, Ph.D.Email PaulaVertinoVertino LabBiomedical GeneticsResearch Interest: Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic interventionMichael Welte, Ph.D.Email MichaelWelteWelte LabBiologyResearch Interest: How microtubule motors, such as kinesins and dyneins, transport organelles and other cargoes throughout the cell.Jack Werren, Ph.D.Email JackWerrenBiologyResearch Interest: Evolutionary GeneticsJiyong Zhao, Ph.D.Email JiyongZhaoLand LabZhao LabBiomedical GeneticsResearch Interest: Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation