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Emeritus Faculty

Primary Faculty

Research Faculty

Secondary Faculty

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FacultyAffiliationInterests
Robert Bambara, Ph.D.
Robert A. Bambara, Ph.D.

Primary Faculty

Emeritus Faculty

Human genome stability, DNA damage response, HIV replication and evolution
Michael Bulger, Ph.D.
Michael D. Bulger, Ph.D.

Secondary Faculty

Bulger Lab

Chromatin domains and long-range activation by enhancers
J. Butler, Ph.D.
J. Scott Butler, Ph.D.

Secondary Faculty

Butler Lab

Regulation of Gene Expression by Targeted Degradation of RNA
Gloria Culver, Ph.D.
Gloria Culver, Ph.D.

Secondary Faculty

Culver Lab

Assembly of the E. coli 30S ribosomal subunit, which is essential for cellular growth, so as to understand how infections might be controlled through selective inhibition of specific assembly control points.
Mark Dumont, Ph.D.
Mark E. Dumont, Ph.D.

Primary Faculty

Dumont Lab

Signal transduction; membrane protein structure, yeast molecular biology
Reyad Elbarbary, Ph.D.
Reyad Elbarbary, Ph.D.

Research Faculty

Maquat Lab

Dmitri Ermolenko, Ph.D.
Dmitri N. Ermolenko, Ph.D.

Primary Faculty

Ermolenko Lab

Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.
Chin-To Fong, M.D.
Chin-To Fong, M.D.

Secondary Faculty

Genetics of orofacial clefts
Peter Gibbs, Ph.D.
Peter E. M. Gibbs, Ph.D.

Research Faculty

Maines Lab

The role of human biliverdin reductase in cell signaling pathways, and the regulation of its expression in the cell.
David Goldfarb, Ph.D.
David S. Goldfarb, Ph.D.

Secondary Faculty

Goldfarb Lab

Molecular mechanisms that control the exchange of molecules and information between the nucleus and cytoplasm
Barry Goldstein, M.D., Ph.D.
Barry M. Goldstein, M.D., Ph.D.

Primary Faculty

Crystallography and structural chemistry of enzyme-ligand interactions.
Elizabeth Grayhack, Ph.D.
Elizabeth Grayhack, Ph.D.

Primary Faculty

Grayhack Lab

Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.
Alan Grossfield, Ph.D.
Alan M. Grossfield, Ph.D.

Primary Faculty

Grossfield Lab

Investigating membranes and membrane proteins via computer simulation
Thomas Gunter, Ph.D.
Thomas E. Gunter, Ph.D.

Primary Faculty

Emeritus Faculty

Membrane transport, bioenergetics, calcium regulation
Karlene Gunter, Ph.D.
Karlene K. Gunter, Ph.D.

Research Faculty

Role of mitochondria in calcium homeostasis, apoptosis and metabolic control
Fred Hagen, Ph.D.
Fred Hagen, Ph.D.

Research Faculty

Hagen Lab

Glycosyltransferases, proteomics, role of glycosylation in development
Jeffrey Hayes, Ph.D.
Jeffrey J. Hayes, Ph.D.

Primary Faculty

Hayes Lab

William A. Bernhard Memorial Lab

DNA structure; chromatin; protein-DNA interactions
Russell Hilf, Ph.D.
Russell Hilf, Ph.D.

Primary Faculty

Emeritus Faculty

Hormone action in mammory cancer; Photodynamic therapy of neoplasia
Jermaine Jenkins, Ph.D.
Jermaine Jenkins, Ph.D.

Research Faculty

Kielkopf Lab

Wedekind Lab

Crystallography of RNA and Protein-RNA complexes
Scott Kennedy, Ph.D.
Scott D.  Kennedy, Ph.D.

Research Faculty

NMR imaging and spectroscopy; Tumor biology; RNA structure determination; anion transport
Clara Kielkopf, Ph.D.
Clara L. Kielkopf, Ph.D.

Primary Faculty

Kielkopf Lab

Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.
George Kimmich, Ph.D.
George Kimmich, Ph.D.

Primary Faculty

Emeritus Faculty

Regulation of neurotransmitter uptake by glial and neuronal cells
Tatsuaki Kurosaki, Ph.D.
Tatsuaki Kurosaki, Ph.D.

Research Faculty

Maquat Lab

mRNA quality control (or mRNA surveillance) mechanism in human cells
Hartmut Land, Ph.D.
Hartmut Land, Ph.D.

Secondary Faculty

Land Lab

Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism
Christopher Lawrence, Ph.D.
Christopher W. Lawrence, Ph.D.

Primary Faculty

Emeritus Faculty

Molecular biology of DNA-damage induced mutagenesis
Xin Li, Ph.D.
Xin Zhiguo Li, Ph.D.

Primary Faculty

Li Lab

Small non-coding RNA regulation in germ cells; paternal aging; transgenerational inheritance.
Bin Liu, Ph.D.
Bin Liu, Ph.D.

Research Faculty

Yu Lab

Regulation of mRNA stability of monocyte chemoattractant protein-1 (MCP-1) by PDGF and Angiotensin II (Ang II) in smooth muscle cells (SMC)
Mahin Maines, Ph.D.
Mahin Maines, Ph.D.

Primary Faculty

Emeritus Faculty

Maines Lab

Heme oxygenases and second messenger gases: CO and NO.
Lynne Maquat, Ph.D.
Lynne Maquat, Ph.D.

Primary Faculty

Maquat Lab

RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.
Elizabeth Mathew, Ph.D.
Elizabeth Mathew, Ph.D.

Research Faculty

Dumont Lab

Structure and functions of G protein coupled receptors (GPCRs), in particular, the yeast GPCR, Ste2p
David Mathews, M.D., Ph.D.
David H. Mathews, M.D., Ph.D.

Primary Faculty

Mathews Lab

Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.
Kermit Mercer, B.S.
Kermit Ray Mercer, B.S.

Primary Faculty

William A. Bernhard Memorial Lab

Electron paramagnetic resonance (epr) research and instrumentation
Benjamin Miller, Ph.D.
Benjamin L. Miller, Ph.D.

Secondary Faculty

Benjamin Miller Lab

Carbohydrate and protein recognition, molecular design, and biomolecular sensing
Tihomir Miralem, Ph.D.
Tihomir Miralem, Ph.D.

Research Faculty

Maines Lab

Joshua Munger, Ph.D.
Joshua C. Munger, Ph.D.

Primary Faculty

Munger Lab

Mechanisms of metabolic network manipulation induced by viral infection and oncogenic mutation.
Eric Phizicky, Ph.D.
Eric Phizicky, Ph.D.

Primary Faculty

Phizicky Lab

tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.
Terry Platt, Ph.D.
Terry Platt, Ph.D.

Primary Faculty

Emeritus Faculty

Molecular mechanisms of gene expression; transcription termination and mRNA 3' and formation in Escherichia coli and yeast; protein-nucleic acid.
Bogdan Polevoda, Ph.D.
Bogdan Polevoda, Ph.D.

Research Faculty

Smith Lab

The two cotranslational processes, cleavage of N-terminal methionine and N-terminal acetylation (N- acetylation).
Maximilian Popp, Ph.D.
Maximilian Popp, Ph.D.

Research Faculty

Maquat Lab

J. Puzas, Ph.D.
J. Edward Puzas, Ph.D.

Secondary Faculty

Puzas Lab

Molecular and Cellular Biology of the Skeletal System
Elena Rustchenko-Bulgac, Ph.D.
Elena P. Rustchenko-Bulgac, Ph.D.

Research Faculty

Rustchenko-Bulgac Lab

Chromosomes instability of human fungal pathogen Candida albicans.
Mohammad Salim, Ph.D.
Mohammad Salim, Ph.D.

Research Faculty

Wedekind Lab

Alan Senior, Ph.D.
Alan E. Senior, Ph.D.

Primary Faculty

Emeritus Faculty

Multidrug-resistance in cancer; ATP synthesis in bacteria and mitochondria
William Simon, Ph.D.
William Simon, Ph.D.

Primary Faculty

Emeritus Faculty

Simon Lab

Optical pattern recognition of biological specimens
Harold Smith, Ph.D.
Harold C. Smith, Ph.D.

Primary Faculty

Smith Lab

RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.
Hironao Wakabayashi, M.D., Ph.D
Hironao Wakabayashi, M.D., Ph.D

Research Faculty

Rustchenko-Bulgac Lab

Structural and functional analyses of factor VIII
Richard Waugh, Ph.D.
Richard E. Waugh, Ph.D.

Secondary Faculty

Waugh Lab

Cell Adhesion, Mechanical and thermodynamic properties of biological membranes; cellular mechanics and function of cytoskeletal proteins
Joseph Wedekind, Ph.D.
Joseph E. Wedekind, Ph.D.

Primary Faculty

Wedekind Lab

Structure and function analysis of gene regulation by riboswitches and microRNAs as a basis for therapeutic development.
Yi-Tao Yu, Ph.D.
Yi-Tao Yu, Ph.D.

Primary Faculty

Yu Lab

RNA modification; pre-mRNA splicing; snRNP biogenesis; telomerase RNA modification and aging; nonsense-disease therapeutics.
Jian Zhu, Ph.D.
Jian Zhu, Ph.D.

Secondary Faculty

Zhu Lab

Host-virus interactions, particularly for HIV and herpes viruses