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Faculty

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Kate Ackerman
Research Interest: Genetics of Congenital Diaphragmatic Hernia in lung development

Brian Altman
Research Interest:

Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism. 

Patricia Chess
Research Interest: Effects of strain on pulmonary epithelium

Ethan Cohen
Research Interest: Wnt signaling in cardiovascular development

Carl D'Angio
Research Interest: Immunizations and infections in the premature infant

David Dean
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease

Andrew Dylag
Research Interest: Understanding how fluctuation in oxygen such as intermittent hypoxia and hyperoxia affect respiratory function in preterm neonates. Coupling oxygen exposures with exposure to viruses to see how they alter lung development in rodent models.

Alison Elder
Research Interest: Toxicology of inhaled ultrafine particles (UFPs) on the lung, cardiovascular and central nervous system

Fabeha Fazal
Research Interest: Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis in acute and chronic lung injury

Jacob Finkelstein
Research Interest: Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.

Steve Georas
Research Interest: Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system

Francis Gigliotti
Research Interest: Pneumocystis carinii pneumonia; Infections in the immunocompromised host

Denise Hocking
Research Interest:

Understanding the mechanisms by which the extracellular matrix protein, fibronectin, affects cell and tissue functions that are critical for wound repair. We study both the structural mechanisms and intracellular signaling events that mediate cell and tissue responses to matrix fibronectin. In turn, we are using this information to develop novel technologies for tissue engineering, and therapeutic approaches to promote tissue regeneration in chronic wounds.

Kirsi Järvinen-Seppo
Research Interest: Food allergies disorders, caused by milk, eggs and peanuts.

Matthew Kottmann
Research Interest: Investigating how novel receptor-based therapeutics modify cytokine production to mitigate lung injury and fibrosis

B. Paige Lawrence
Research Interest: Influence of environmental factors on the development and function of the immune system

Augusto Litonjua
Research Interest: Investigating factors that both increase and decrease the risk of developing asthma, wheezing, and allergic disorders in childhood

John Lueck
Research Interest: Determining the therapeutic promise of engineered tRNAs for treatment of nonsense associated diseases and investigating the pathomechanisms of skeletal muscle weakness and wasting in myotonic dystrophy

Thomas Mariani
Research Interest: Genetic mechanisms of susceptibility to chronic lung diseases, focusing on developmental antecedents and influence of environmental factors.

Matthew McGraw
Research Interest: Epithelial injury and abnormal repair in pediatric and adult lung disease

Ravi Misra
Research Interest: Understanding mechanisms of pathology in common inflammatory conditions of children

Michael O'Reilly
Research Interest: Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.

Günter Oberdörster
Research Interest: Biokinetics, Effects and Mechanisms of Inhaled Micro- and Nano- Particles: Dosimetry, Risk Extrapolation and Risk Assessment

Anthony Pietropaoli
Research Interest: Team approaches to patient-centered, clinical and translational investigation in sepsis and critical illness

Gloria Pryhuber
Research Interest: Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.

Homaira Rahimi
Research Interest: Juvenile Idiopathic arthritis. Imaging of lymph nodes as a martyr for arthritic flare in RA, lymphangiogenesis in Arthritic flare in murine model of erosive arthritis.

Arshad Rahman
Research Interest: Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.

Irfan Rahman
Research Interest: Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants.

Kristen Scheible
Research Interest: Neonatal immunology; T cell function in preterm infants

David Topham
Research Interest: Multiple roles of virus-specific Band T cells in determining the outcome of viral infection of the respiratory tract. Long term protective effect of immunological mechanisms.

R. White
Research Interest: Role of mitochondria in hypoxic pulmonary vasoconstriction.

Jacqueline Williams
Research Interest: Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.

Terry Wright
Research Interest: Immune response and Pathogenesis of lung injury and related pulmonary inflammation