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Primary Faculty

Jean Bidlack
Research Interest: Pharmacology of brain and lymphocytic opioid receptors
Robert Dirksen
Research Interest: Molecular Mechanisms of Calcium Signaling in Striated Muscle
Manoela Fogaça
Research Interest:

Understanding the molecular basis of behaviors relevant to stress and the actions of fast antidepressant and anxiolytic drugs, aiming to identify specific circuits, neuronal subpopulations and synaptic mechanisms involved in these responses.

Robert Freeman
Research Interest: Molecular biology of programmed cell death
Angela Glading
Research Interest: Role of cell-cell contact in regulating cellular function in both the normal and disease state
Suzanne Haber
Research Interest:

Basal ganglia and degenerative diseases

Denise Hocking
Research Interest:

Understanding the mechanisms by which the extracellular matrix protein, fibronectin, affects cell and tissue functions that are critical for wound repair. We study both the structural mechanisms and intracellular signaling events that mediate cell and tissue responses to matrix fibronectin. In turn, we are using this information to develop novel technologies for tissue engineering, and therapeutic approaches to promote tissue regeneration in chronic wounds.

Paul Kammermeier
Research Interest: G protein coupled receptor signaling and modulation of ion channels in neurons
Whasil Lee
Research Interest:

Mechanotransduction of musculoskeletal cells and associated human disease; Physiology and pathophysiology of mechanosensitive ion channels

John Lueck
Research Interest: Determining the therapeutic promise of engineered tRNAs for treatment of nonsense associated diseases and investigating the pathomechanisms of skeletal muscle weakness and wasting in myotonic dystrophy
David MacLean
Research Interest: Mechanisms of neurotransmitter receptor function
Cesare Orlandi
Research Interest: Orphan G protein coupled receptors in brain and visual systems
A. William Tank
Research Interest: Regulation of tyrosine hydroxylase gene expression in the nervous system
Verda Thomas
Research Interest: Identification of relevant cutting-edge microscopy technologies for implementation at the University of Rochester. Application of quantitative imaging and analysis techniques to a variety of research projects.

Director, Center for Advanced Light Microscopy and Nanoscopy

Houhui Xia
Research Interest: Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health
David Yule
Research Interest: Mechanisms Underlying Ca2+ Signaling Events in Exocrine Cells

Research Faculty

John Onukwufor
Research Interest:

Elucidate the molecular mechanisms of divalent metal neurotoxicity and mitochondrial dysfunction in Alzheimer's disease pathogenesis

Takahiro Takano
Research Interest: Purinergic signaling in peripheral nociceptive nerve, neurovascular coupling, stroke injury and astrocytic communication

Secondary Faculty

Douglas Anderson
Research Interest: LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.
Bradford Berk
Research Interest: Signaling transduction mechanisms in the vascular system
Paul Brookes
Research Interest: Cardioprotection against ischemia-reperfusion (IR) injury. Role of Mitochondria and metabolism in ischemic preconditioning and anesthetic preconditioning.
David Bushinsky
Research Interest: Internal Medicine
Laura Calvi
Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow
Chike Cao
Research Interest:

The role of CAv 1, 2 in tendon formation and heterotopic bone (HO) formation

Kavaljit Chhabra
Research Interest: Molecular basis of glucose sensing in the brain and beta cells
David Dean
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease
Ian Dickerson
Research Interest: Molecular mechanisms of neuropeptide signal transduction
Roman Eliseev
Research Interest:

Role of Mitochondria in regulation of cell fate in normal stem cells and cancer cells

Megan Falsetta
Research Interest:

Translational women’s health research; To identify previously unknown mechanisms of disease for disabling vulvar conditions, namely vulvodynia and lichens

Fabeha Fazal
Research Interest: Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis in acute and chronic lung injury
Robert Gross
Research Interest: Molecular pharmacology of neuronal signal transduction and ion channel activity
Stephen Hammes
Research Interest: Androgen Effects on Reproduction and Cancer
Minsoo Kim
Research Interest: Innate and adaptive immune responses and cancer immunotherapy
Nancy Krieger
Nancy S. Krieger, Ph.D.

Sergiy Nadtochiy
Research Interest: Human Structure and Function
George Porter
Research Interest: Mechanisms that control the development of the heart
Arshad Rahman
Research Interest: Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.
Eileen Redmond
Research Interest:

Vascular Effects of Alcohol-role of Notch

Peter Shrager
Peter Shrager, Ph.D.
Research Interest:

Neuron-neuroglia interactions

Eric Small
Research Interest:

To better understand the mechanisms that control cell identity and lineage commitment by studying the transcriptional regulation and function of cardiac tissue-restricted genes

Richard Waugh
Research Interest:

Cell Adhesion, Mechanical and thermodynamic properties of biological membranes; cellular mechanics and function of cytoskeletal proteins

R. White
Research Interest: Role of mitochondria in hypoxic pulmonary vasoconstriction.
Andrew Wojtovich
Research Interest: Optogenetics to study the roles of Reactive Oxygen Species (ROS) in mitochondrial physiology and stress signaling.
Jing Wu
Research Interest:

Vascular Biology and Inflammation in Hypertension and Kidney Disease

Emeritus Faculty

Marion Anders
Research Interest:

Metabolism and toxicity of halogen- and sulfur-containing chemicals and on the design and synthesis of mitochondrially targeted drugs

Martha Blair
Research Interest: Neural and neuroendocrine control of cardiovascular function
Patricia Hinkle
Research Interest: Molecular Mechanisms of Cell Regulation
Camillo Peracchia
Research Interest: Gap junctions, connexins, cell communication, calmodulin, calcium, channel gating
Ingrid Sarelius
Research Interest: Vascular cell communication and signaling
Trevor Shuttleworth
Research Interest: The nature of the conductances responsible for agonist-induced Ca2+ entry in non-excitable cells, and their roles in modulating overall Ca2+ signals