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Publications

2016 Publications

Carr R, Koziol-White C, Zhang J, Lam H, Ahn SS, Tall GG, Panettieri RA, Benovic JL. (2016) Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent MechanismsMol Pharmacol. 89(1):94-104.

Carstensen EL, Parker KJ, Dalecki D, Hocking DC. (2016) Biological Effects of Low-Frequency Shear Strain: 1. Physical Descriptors Ultrasound Med Biol. 42(1)1-15.

Dougherty DD, Chou T, Corse AK, Arulpragasam AR, Widge AS, Cusin C, Evans KC, Greenberg BD, Haber SN, Deckersbach T. (2016) Acute deep brain stimulation changes in regional cerebral blood flow in obsessive-compulsive disorder J Neurosurg. [Epub ahead of print]

Gerber S, Alzayady KJ, Burglen L, Brémond-Gignac D, Marchesin V, Roche O, Rio M, Funalot B, Calmon R, Durr A, Gil-da-Silva-Lopes VL, Ribeiro Bittar MF, Orssaud C, Héron B, Ayoub E, Berquin P, Bahi-Buisson N, Bole C, Masson C, Munnich A, Simons M, Delous M, Dollfus H, Boddaert N, Lyonnet S, Kaplan J, Calvas P, Yule DI, Rozet JM, Fares Taie L. (2016) Recessive and Dominant De Novo ITPR1 Mutations Cause Gillespie SyndromeAm J Hum Genet. [Epub ahead of print]

Haber SN. (2016) Corticostriatal circuitryDialogues Clin Neurosci. 18(1):7-21.

Sánchez-Fernández G, Cabezudo S, Caballero Á, García-Hoz C, Tall GG, Klett J, Michnick SW, Mayor F Jr, Ribas C. (2016) Protein kinase C ζ interacts with a novel binding region of Gαq to act as functional effector proteinJ Biol Chem. [Epub ahead of print]

Sneyd J, Means S, Zhu D, Rugis J, Won JH, Yule DI. (2016) Modeling Calcium Waves in an Anatomically Accurate Three-Dimensional Parotid Acinar CellJ Theor Biol. [Epub ahead of print]

Surve CR, To JY, Malik S, Kim M, Smrcka AV. (2016) Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and GβγSci Signal. 23;9(416):ra22.

Yang T, Colecraft HM. (2016) Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channelsChannels. 10(1):38-44.

2015 Publications

Alzayady KJ, Sebé-Pedrós A, Chandrasekhar R, Wang L, Ruiz-Trillo I, Yule DI. (2015) Tracing the Evolutionary History of Inositol, 1, 4, 5-trisphosphate receptor: Insights from Analyses of Capsaspora owczarzaki Ca2+ Release Channel Orthologs. Mol Biol Evol. 32(9):2236-2253.

Boschi NM, Takeuchi K, Sterling C, Tank AW. (2015) Differential expression of polycytosine-binding protein isoforms in adrenal gland, locus coeruleus and midbrainNeuroscience. 12;286:1-12.

Brand CS, Sadana R, Malik S, Smrcka AV, Dessauer CW. (2015) Adenylyl Cyclase 5 Regulation by Gβγ Involves Isoform Specific Use of Multiple Interaction SitesMol Pharmacol. 88:758-767.

Brennan JR, Hocking DC. (2015) Cooperative effects of fibronectin matrix assembly and initial cell-substrate adhesion strength in cellular self-assembly Acta biomaterialia. [Epub ahead of print]

Dalecki D, Mercado KP, Hocking DC. (2015) Quantitative Ultrasound for Nondestructive Characterization of Engineered Tissues and Biomaterials. Ann Biomed Eng. [Epub ahead of print]

Dalecki D, Hocking DC. (2015) Ultrasound technologies for biomaterials fabrication and imagingAnnals of biomedical engineering. 43(3):747-761.

Dusaban SS, Kunkel MT, Smrcka AV, Brown JH. (2015) Thrombin Promotes Sustained Signaling and Inflammatory Gene Expression through the CDC25 and Ras Associating Domains of Phospholipase C-epsilonJ Biol Chem. 290(44):26776-26783.

Georgiou DK, Dagnino-Acosta A, Lee CS, Griffin DM, Wang H, Lagor WR, Pautler RG, Dirksen RT, Hamilton SL. (2015) Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism. J Biol Chem. 290(39):23751-65.

Hammond CL, Wheeler SG, Ballatori N, Hinkle PM. (2015) Ostα-/- mice are not protected from western diet-induced weight gainPhysiol Rep. 3(1):e12263.

Hedgepeth SC, Garcia MI, Wagner LE 2nd, Rodriguez AM, Chintapalli SV, Snyder RR, Hankins GD, Henderson BR, Brodie KM, Yule DI, van Rossum DB, Boehning D. (2015) The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium releaseJ Biol Chem. 290 (11):7304-7313.

Jbabdi S, Sotiropoulos SN, Haber SN, Van Essen DC, Behrens TE. (2015) Measuring macroscopic brain connections in vivoNat Neurosci. 18(11):1546-1555.

Kammermeier PJ. (2015) Constitutive activity of metabotropic glutamate receptor 7.BMC Neurosci. 24 (16):17.

Kudrick N, Chan O, La Gamma EF, Kim JL, Tank AW, Sterling C, Nankova BB. (2015) Posttranscriptional regulation of adrenal TH gene expression contributes to the maladaptive responses triggered by insulin-induced recurrent hypoglycemia. Physiol Rep. 22;3(2).

Lamboley CR, Kake Guena SA, Touré F, Hébert C, Yaddaden L, Nadeau S, Bouchard P, Wei-LaPierre L, Lainé J, Rousseau EC, Frenette J, Protasi F, Dirksen RT, Pape PC. (2015) New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin.J Gen Physiol. 145(2):127-153.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. (2015) Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle functionSkelet Muscle. 29;5:4.

Lefever M, Li Y, Anglin B, Muthu D, Giuvelis D, Lowery JJ, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. (2015) Structural Requirements for CNS Active Opioid Glycopeptides.J Med Chem. 58:5728:5871.

Liu X, Wang C, Fujita T, Malmstrom HS, Nedergaard M, Ren YF, Dirksen RT. (2015) External Dentin Stimulation Induces ATP Release in Human Teeth. J Dent Res. 94(9):1259-1266.

Liu W, Wei-LaPierre L, Klose A, Dirksen RT, Chakkalakal JV. (2015) Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctionsElife. 27:4.

Malik S, deRubio RG, Trembley M, Irannejad R, Wedegaertner PB, Smrcka AV. (2015) G Protein βγ Subunits Regulate Cardiomyocyte Hypertrophy Through a Perinuclear Golgi Phosphatidylinositol 4-phosphate Hydrolysis Pathway.Mol Biol Cell. 26(6):1188-1198.

Malik S, Dolan TM, Maben ZJ, Hinkle PM. (2015) ACTH Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane. J Biol Chem. 290(46):27972-27985.

Mercado KP, Langdon J, Helguera M, McAleavey SA, Hocking DC, Dalecki D. (2015) Scholte wave generation during single tracking location shear wave elasticity imaging of engineered tissueThe Journal of the Acoustical Society of America. 138(2):EL138-44.

Mercado KP, Helguera M, Hocking DC, Dalecki D. Noninvasive Quantitative Imaging of Collagen Microstructure in Three-Dimensional Hydrogels Using High-Frequency Ultrasound. Tissue engineering. Part C, Methods. 21(7):671-682.

Michelucci A, Paolini C, Canato M, Wei-Lapierre L, Pietrangelo L, De Marco A, Reggiani C, Dirksen RT, Protasi F (2015) Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death. Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death. Anesthesiology. 123:603-617.

Murrant CL, Sarelius IH. (2015) Local control of blood flow during active hyperAemia: what kinds of integration are important? J Physiol. 593(21)4699-4711.

Paolini C, Quarta M, Wei-LaPierre L, Michelucci A, Nori A, Reggiani C, Dirksen RT, Protasi F. (2015) Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice. Skelet Muscle. 5:10.

Pietrangelo L, D'Incecco A, Ainbinder A, Michelucci A, Kern H, Dirksen RT, Boncompagni S, Protasi F. (2015) Age-dependent uncoupling of mitochondria from Ca2+ release units in skeletal muscle.Oncotarget. 6(34):35358-35371.

Rebbeck RT, Willemse H, Groom L, Casarotto MG, Board PG, Beard NA, Dirksen RT, Dulhunty AF. (2015) Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β1a subunit. Skelet Muscle. 5:23.

Rocheleau AD, Sumagin R, Sarelius IH, King MR. (2015) Simulation and Analysis of Tethering Behavior of Neutrophils with PseudopodsPLoS One. 10(6):e0128378.

Rodriguez-Romaguera J, Do-Monte FH, Tanimura Y, Quirk GJ, Haber SN. (2015) Enhancement of Fear Extinction with Deep Brain Stimulation: Evidence for Medial Orbitofrontal Involvement. Neuropsychopharmacology. 40 (7):1726-1733.

Rodriguez-Romaguera J, Greenberg BD, Haber SN, Quirk GJ. (2015) A Cross Species Approach to Understanding DBS Modulation of Fear. Brain Stimul. 8(5):986-988.

Sarelius IH, Glading AJ. (2015) Control of vascular permeability by adhesion molecules.Tissue Barriers. 3 (1-2):e985954.

Sarelius IH, Titus PA, Maimon N, Okech W, Wilke-Mounts SJ, Brennan JR, Hocking DC. (2015) Extracellular matrix fibronectin initiates endothelium-dependent arteriolar dilation via the heparin-binding, matricryptic RWRPK sequence of FNIII1The Journal of physiology. [Epub ahead of print]

Smrcka AV. (2015) Regulation of Phosphatidylinositol-specific Phospholipase C at the Nuclear Envelope in Cardiac Myocytes. J Cardiovasc Pharmacol. 65 (3):203-210

Smrcka AV. (2015) Fingerprinting G protein-coupled receptor signaling. Sci Signal.8(405).

Stoveken HM, Hajduczok AG, Xu L, Tall GG. (2015) Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.Proc Natl Acad Sci USA. 112(19)6194-6199.

Tank AW, Lee Wong D. (2015) Peripheral and central effects of circulating catecholamines
Compr Physiol. 5 (1):1-15.

Vervloessem T, Yule DI, Bultynck G, Parys JB. (2015) The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca²?-release channel. Biochim Biophys Acta. Biochim Biophys Acta. 1853(9):1992-2005.

Yang T, Justus S, Li Y, Tsang SH. (2015) BEST1: the Best Target for Gene and Cell Therapies.Molecular therapy. 23(12):1805-1809.

2014 Publications

Gehret AU, Hinkle PM. (2014) siRNA screen identifies the phosphatase acting on the G protein-coupled thyrotropin-releasing hormone receptor. ACS Chem Biol. 8 (3):588-598.

Gildner CD, Roy DC, Farrar CS, Hocking DC. (2014) Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function. Matrix Biol. 34:33-45.

Goonasekera SA, Davis J, Kwong JQ, Accornero F, Wei-Lapierre L, Sargent MA, Dirksen RT, Molkentin JD. (2014) Enhanced Ca2+ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy. Hum Mol Genet. 23 (14):3706-3715.

Haber SN, Behrens TE. (2014) The Neural Network Underlying Incentive-Based Learning: Implications for Interpreting Circuit Disruptions in Psychiatric Disorders.Neuron. 83 (5):1019-1039.

Heilbronner SR, Haber SN. (2014) Frontal cortical and subcortical projections provide a basis for segmenting the cingulum bundle: implications for neuroimaging and psychiatric disorders.J Neurosci. 34 (30):10041-10054.

Hocking DC, Raeman CH, Dalecki D. (2014) Investigation of effects of ultrasound on dermal wound healing in diabetic mice. J Acoust Soc Am. 135 (4):2370.

Hocking DC, Kennedy GA, Sundram S. (2014) Mental Disorders in Asylum Seekers: The Role of the Refugee Determination Process and Employment. J Nerv Ment Dis. 203 (1):28-32.

Kamal FA, Mickelsen DM, Wegman KM, Travers JG, Moalem J, Hammes SR, Smrcka AV, Blaxall BC. (2014) Simultaneous adrenal and cardiac g-protein-coupled receptor-gβγ inhibition halts heart failure progression.J Am Coll Cardiol. 63 (23):2549-2557.

Kan W, Adjobo-Hermans M, Burroughs M, Faibis G, Malik S, Tall GG, Smrcka AV. (2014) M3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency.J Biol Chem. 289 (16):11206-11218.

Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe JI. (2014) Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents. J Immunol. 193 (7):3803-3815.

Li Y, St Louis L, Knapp BI, Muthu D, Anglin B, Giuvelis D, Bidlack JM, Bilsky EJ, Polt R. (2014) Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to β-endorphin?.J Med Chem. 57 (6):2237-2246.

Liebscher I, Ackley B, Araç D, Ariestanti DM, Aust G, Bae BI, Bista BR, Bridges JP, Duman JG, Engel FB, Giera S, Goffinet AM, Hall RA, Hamann J, Hartmann N, Lin HH, Liu M, Luo R, Mogha A, Monk KR, Peeters MC, Prömel S, Ressl S, Schiöth HB, Sigoillot SM, Song H, Talbot WS, Tall GG, White JP, Wolfrum U, Xu L, Piao X. (2014) New functions and signaling mechanisms for the class of adhesion G protein-coupled receptorsAnn N Y Acad Sci. 1333:43-64.

Maimon N, Titus PA, Sarelius IH. (2014) Pre-exposure to adenosine, acting via A2A receptors on endothelial cells, alters the PKA-dependence of adenosine-induced dilatation in skeletal muscle resistance arterioles. J Physiol. 592 (Pt12):2575-2590.

Mercado KP, Helguera M, Hocking DC, Dalecki D. (2014) Characterizing collagen microstructure using high frequency ultrasound. J Acoust Soc Am. 135 (4):2373.

Mercado KP, Helguera M, Hocking DC, Dalecki D. (2014) Estimating Cell Concentration in Three-Dimensional Engineered Tissues Using High Frequency Quantitative Ultrasound. Ann Biomed Eng. 42 (6):1292-1304.

O-Uchi J, Jhun BS, Xu S, Hurst S, Raffaello A, Liu X, Yi B, Zhang H, Gross P, Mishra J, Ainbinder A, Kettlewell S, Smith GL, Dirksen RT, Wang W, Rizzuto R, Sheu SS. (2014) Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter. Antioxid Redox Signal. 21 (6):863-879.

Oldenburger A, Timens W, Bos S, Smit M, Smrcka AV, Laurent AC, Cao J, Hylkema M, Meurs H, Maarsingh H, Lezoualc'h F, Schmidt M. (2014) Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smokeFASEB J. 28 (11):4617-4628.

Papasergi MM, Patel BR, Tall GG. (2014) The G protein α chaperone Ric-8 as a potential therapeutic targetMol Pharmacol. 87 (1):52-63.

Riazi S, Kraeva N, Muldoon SM, Dowling J, Ho C, Petre MA, Parness J, Dirksen RT, Rosenberg H (2014) Malignant hyperthermia and the clinical significance of type-1 ryanodine receptor gene (RYR1) variants: proceedings of the 2013 MHAUS Scientific Conference.Can J Anaesth. 61:1040-1049.

Ruisanchez É, Dancs P, Kerék M, Németh T, Faragó B, Balogh A, Patil R, Jennings BL, Liliom K, Malik KU, Smrcka AV, Tigyi G, Benyó Z. (2014) Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase.FASEB J. 28 (2):880-890.

Sevastyanova TN, Kammermeier PJ. (2014) Cooperative Signaling Between Homodimers of Metabotropic Glutamate Receptors 1 and 5.Mol Pharmacol. 86 (5):492-504.

Sromek AW, Provencher BA, Russell S, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. (2014) Preliminary Pharmacological Evaluation of Enantiomeric Morphinans.ACS Chem Neurosci. 5 (2): 93-99.

Surve CR, Lehmann D, Smrcka AV. (2014) A Chemical Biology Approach Demonstrates GTP-binding Protein Gβγ Subunits are Sufficient to Mediate Directional Neutrophil Chemotaxis.J Biol Chem. 289 (25):17791-17801.

Thompson JL, Shuttleworth TJ. (2014) AKAP79-mediated PKA-phosphorylation of STIM1 determines selective activation of ARC channels, a store-independent Orai channel.
J Physiol. [Epub ahead of print]

Tziortzi AC, Haber SN, Searle GE, Tsoumpas C, Long CJ, Shotbolt P, Douaud G, Jbabdi S, Behrens TE, Rabiner EA, Jenkinson M, Gunn RN.(2014) Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography.Cereb Cortex. 24 (5):1165-1177.

Vervloessem T, Yule DI, Bultynck G, Parys JB. (2014) The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca<sup>2+</sup>-release channel.Biochim Biophys Acta. [Epub ahead of print]

Wagner LE 2nd, Groom LA, Dirksen RT, Yule DI. (2014) Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clamp.Cell Calcium. 56:96-107.

Wheeler SG, Hammond CL, Jornayvaz FR, Samuel VT, Shulman GI, Soroka CJ, Boyer JL, Hinkle PM, Ballatori N. (2014) Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity. Am J Physiol Gastrointest Liver Physiol. 306:G425-G438.

Yarotskyy V, Dirksen RT. (2014) RGK proteins: fashioning muscle with “Rad” new brakes.Channels (Austin). 8 (4):286-7.

Yarotskyy V, Dirksen RT (2014). Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibersBiophys J. 107 (9):2027-2036.

Yule DI. (2014) Special issue: Ca²? signaling and secretory function. Preface. Cell Calcium. 55(6):281.

2013 Publications

Alzayady KJ, Chandrasekhar R, Yule DI. (2013) Fragmented Inositol 1,4,5-Trisphosphate Receptors Retain Tetrameric Architecture and Form Functional Ca2+ Release Channels. J. Biol. Chem. 288 (16):11122-11134.

Alzayady KJ, Wagner LE 2nd, Chandrasekhar R, Monteagudo AM, Godiska R, Tall GG, Joseph SK, Yule DI. (2013) Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits. J Biol Chem. 288 (41) :29772-29784.

Anders MW. (2013) Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion 13 (5) 454-463.

Beqollari D, Kammermeier PJ. (2013) The interaction between mGluR1 and the calcium channel Cav2.1 preserves coupling in the presence of long Homer proteins. Neuropharmacology 66:302-310.

Chan P, Thomas CJ, Sprang SR, Tall GG. (2013) Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein alpha subunits. Proc. Natl. Acad. Sci. U.S.A. 110 (10):3794-3799.

Dusaban SS, Purcell NH, Rockenstein E, Masliah E, Cho MK, Smrcka AV, Brown JH. (2013) Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proc. Natl. Acad. Sci. U.S.A. 110 (9):3609-3614.

Garvin KA, Dalecki D, Yousefhussien M, Helguera M, Hocking DC. (2013) Spatial patterning of endothelial cells and vascular network formation using ultrasound standing wave fields. J Acoust Soc Am. 134 (2):1483-1490.

Garvin KA, Vanderburgh J, Hocking DC, Dalecki D. (2013) Controlling collagen fiber microstructure in three-dimensional hydrogels using ultrasound. J Acoust Soc Am. 134 (2):1491-1502.

Gunter TE, Gerstner B, Gunter KK, Malecki J, Gelein R, Valentine WM, Aschner M, Yule DI. (2013) Manganese Transport via the Transferrin Mechanism. Neurotoxicology 34:118-127.

Haber SN, Heilbronner SR. (2013) Translational research in OCD: circuitry and mechanisms. Neuropsychopharmacology 38 (1):252-253.

Haber SN, Safadi Z, Milad MR. (2013) Meeting report: "Depression and Anxiety Spectrum disorders: from basic science to the clinic and back". Biol. Mood Anxiety Disord. 3 (1):6.

Haynes WIA, Haber SN. (2013) The organization of prefrontal-subthalamic inputs in primates provides an anatomical substrate for both functional specificity and integration: implications for Basal Ganglia models and deep brain stimulation. J. Neurosci. 33 (11):4804-4814.

Hoot MR, Sypek EI, Reilley KJ, Carey AN, Bidlack JM, McLaughlin JP. (2013) Inhibition of Gβγ-subunit signaling potentiates morphine-induced antinociception but not respiratory depression, constipation, locomotion, and reward. Behav. Pharmacol. 24 (2):144-152.

Jbabdi S, Lehman JF, Haber SN, Behrens TE. (2013) Human and Monkey Ventral Prefrontal Fibers Use the Same Organizational Principles to Reach Their Targets: Tracing versus Tractography. J. Neurosci. 33 (7):3190-3201.

Kemeny LV, Schnur A, Czepan M, Rakonczay Z Jr, Gal E, Lonovics J, Lázár G, Simonka Z, Venglovecz V, Maleth J, Judak L, Németh IB, Szabó K, Almássy J, Virag L, Geisz A, Tiszlavicz L, Yule DI, Wittmann T, Varro A, Hegyi P. (2013) Na+/Ca2+ exchangers regulate the migration and proliferation of human gastric myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 305 (8):G552-563

Kraeva N, Zvaritch E, Rossi AE, Goonasekera SA, Zaid H, Frodis W, Kraev A, Dirksen RT, Maclennan DH, Riazi S. (2013) Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease. Neuromuscul Disord. 23 (2):120-132.

Lefebvre R, Legrand C, Groom L, Dirksen RT, Jacquemond V. (2013) Ca(2+) Release in Muscle Fibers Expressing R4892W and G4896V Type 1 Ryanodine Receptor Disease Mutants.PLoS One 8 (1):e54042.

Mailly P, Aliane V, Groenewegen HJ, Haber SN, Deniau JM. (2013) The Rat Prefrontostriatal System Analyzed in 3D: Evidence for Multiple Interacting Functional Units. J. Neurosci. 33 (13) :5718-5727.

McLaughlin NC, Didie ER, Machado AG, Haber SN, Eskandar E, Greenberg BD. (2013) Improvements in anorexia symptoms after deep brain stimulation for intractable obsessive-compulsive disorder. Biol Psychiatry. 73 (9):e29-e31.

Monaco G, Decrock E, Nuyts K, Wagner Ii LE, Luyten T, Strelkov SV, Missiaen L, De Borggraeve WM, Leybaert L, Yule DI, De Smedt H, Parys JB, Bultynck G. (2013) Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to Inhibit the IP3 Receptor. PLoS One 8 (8):e73386.

Oner SS, Maher EM, Gabay M, Tall GG, Blumer JB, Lanier SM. (2013) Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.J. Biol. Chem. 288 (5):3003-3015.

Provencher BA, Sromek AW, Li W, Russell SE, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. (2013) Synthesis and Pharmacological Evaluation Aminothiazolomorphinans at Mu and Kappa Opioid Receptors. J Med Chem. 14;56(21):8872-8878.

Ram R, Wescott AP, Varandas K, Dirksen RT, Blaxall BC. (2013) Mena associates with Rac1 and modulates connexin43 remodeling in cardiomyocytes.Am J Physiol Heart Circ Physiol. 306 (1):H154-H159.

Reifler A, Lenk GM, Li X, Groom L, Brooks SV, Wilson D, Bowerson M, Dirksen RT, Meisler MH, Dowling JJ. (2013) Murine Fig4 is dispensable for muscle development but required for muscle function. Skelet Muscle 3 (1):21.

Roy DC, Hocking DC. (2013) Recombinant Fibronectin Matrix Mimetics Specify Integrin Adhesion and Extracellular Matrix Assembly. Tissue Eng. Part A. 19 (3-4):558-570.

Roy DC, Mooney NA, Raeman CH, Dalecki D, Hocking DC. (2013) Fibronectin matrix mimetics promote full-thickness wound repair in diabetic mice. Tissue Eng Part A. 19 (21-22):2517-2526.

Sebag JA, Zhang C, Hinkle PM, Bradshaw AM, Cone RD. (2013) Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish. Science 341 (6143):278-281.

Smrcka AV. (2013) Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics. Trends Pharmacol. Sci. 34 (5):290-298.

Sevilla CA, Dalecki D, Hocking DC. (2013) Regional Fibronectin and Collagen Fibril Co-Assembly Directs Cell Proliferation and Microtissue Morphology.PLoS One. 8 (10) :e77316.

Sumagin R, Sarelius IH. (2013) Emerging Understanding of Roles for Arterioles in Inflammation. Microcirculation 20 (8):679-692.

Sun Z, Smrcka AV, Chen S. (2013) WDR26 functions as a scaffolding protein to promote Gβγ-mediated PLCβ2 activation in leukocytes. J. Biol. Chem. 288 (23):16715-16725.

Tall GG. (2013) Ric-8 regulation of heterotrimeric G proteins. J. Recept. Signal. Transduct. Res. 33 (3):139-143.

Tall GG, Patel BR, Chan P. (2013) Ric-8 folding of G proteins better explains Ric-8 apparent amplification of G protein-coupled receptor signaling. Proc. Natl. Acad. Sci. U.S.A. 110 (34):E3148.

Thompson JL, Shuttleworth TJ. (2013) Exploring the unique features of the ARC channel, a Store-independent Orai channel. Channels (Austin) 7 (5):364-373.

Thompson JL, Shuttleworth TJ. (2013) How Many Orai's Does It Take to Make a CRAC Channel? Sci. Rep. 3:1961.

Thompson JL, Shuttleworth TJ. (2013) Molecular basis of activation of the arachidonate-regulated ARC channel, a store-independent Orai channel, by plasma membrane STIM1. J. Physiol. 591 (Pt 14):3507-3523.

Thompson JL, Mignen O, Shuttleworth TJ. (2013) The ARC Channel-An Endogenous Store-Independent Orai Channel. Curr Top Membr. 71:125-148.

Tziortzi AC, Haber SN, Searle GE, Tsoumpas C, Long CJ, Shotbolt P, Douaud G, Jbabdi S, Behrens TE, Rabiner EA, Jenkinson M, Gunn RN. (2013) Connectivity-Based Functional Analysis of Dopamine Release in the Striatum Using Diffusion-Weighted MRI and Positron Emission Tomography. Cereb. Cortex. 24 (5):1165-1177.

Vanalstine MA, Wentland MP, Alvarez J, Cao Q, Cohen DJ, Knapp BI, Bidlack JM. (2013) Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. Bioorg. Med. Chem. Lett. 23 (7):2128-2133.

Wei-Lapierre L, Carrell EM, Boncompagni S, Protasi F, Dirksen RT. (2013) Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue. Nat Commun. 4:2805.

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