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Development of gene delivery techniques to the lung using electroporation and modified nucleic acids

The Multifactorial Roles of Platelets in Malaria Infection

Scar formation and inflammatory signaling after a myocardial infarction

Tau Post-Translational Modifications mediate cellular dysfunctions in Alzheimer’s Disease

Exploring neurophysiological changes of multisensory processing in knockout mouse models of childhood rare diseases

Phagocytosis of osteoblast in the MDS-like environment

The mechanism behind sexual dimorphism in TNF-induced erosive inflammatory arthritis

Presenilin 1-dependent regulation of lysosome function and tau clearance

Neuro-skeletal biology and tissue regeneration

Mitochondrial genetics and function as determinants of mesenchymal stem cell fate

T. gondii-induced peripheral tissue reprogramming

Inflammatory processes involved in the onset and development of Osteoarthritis

The effect of mitochondrial dysfunction and oxidative stress on tau pathology.

Vision loss in CLN3 disease using a patient-derived hiPSC model

The molecular mechanisms leading to the onset and progression of osteoarthritis in aging and after injury and development of therapeutic treatments for articular cartilage protection and regeneration

Role of Jag1 during Inner Ear development

The role of senescent cells in fracture healing

Megakaryocytes and platelets roles' in immunity and Origin of lung megakaryocytes and their roles in shaping immune responses

Investigating ligand presentation by XNC4, a non-polymorphic MHC class I-like molecule that confers resistance to infections by non-TB mycobacteria in Xenopus

The role of repetitive elements in zygotic genome activation.

Investigating Lymphatics in Inflammatory-Erosive Arthritis

Identifying the contributions of the mycobiome to skin in health and disease.

https://quintanalab.bwh.harvard.edu/research/

The effects of modulating Sigma-1 receptor signaling on pathogenic activities of astrocytes in Parkinson's Disease

Transcription factor regulation of progenitor cells during development

Elucidating the Epigenetic Mechanisms that Regulate stress and steady-state Erythropoiesis, with the overarching goal of ameliorating symptoms in hemoglobinopathies.

Age differences in proactive and reactive cognitive-motor interactions

Using optogenetics to explore chimeric antigen receptor (CAR) T cell effector function in solid tumors

Mechanisms underlying TANGO2 Deficiency Disorder in a C. elegans model.

Investigating the role of the immune system in the development of cancer cachexia during pancreatic cancer.

Investigating mechanisms of bone marrow microenvironmental dysfunction in acute myeloid leukemia

Investigating the mechanisms of pancreatic cancer dormancy

Epigenetic regulation of breast cancer invasion

Role of energy metabolism in regulating mesenchymal stem cell fate. Mitochondrial function in adipogenic versus osteogenic lineages.