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Faculty

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Affiliated Faculty

Kate Ackerman, M.D.

Kate Ackerman, M.D.

Associate Professor

Ackerman Lab

Pediatrics - Congenital Diaphragmatic Hernia

Lisa Beck, M.D.

Lisa Beck, M.D.

Associate Professor

Beck Lab

Dermatology - Treatment of atopic dermatitis and eczema

Bradford Berk, M.D., Ph.D.

Bradford Berk, M.D., Ph.D.

Professor

Berk Lab

Medicine - Signal transduction mechanisms in the vasculature

Paul Brookes, Ph.D.

Paul Brookes, Ph.D.

Associate Professor

Brookes Lab

Anesthesiology - Mitochondria and free radicals in cardiac ischemia-reperfusion

Edward Brown, Ph.D.

Edward Brown, Ph.D.

Associate Professor

Brown Lab

Biomedical Engineering - Multiphoton Laser Scanning Microscopy, novel in vivo imaging and measurement techniques, tumor biology, angiogenesis

W. Richard Burack, M.D., Ph.D.

W. Richard Burack, M.D., Ph.D.

Associate Professor

Burack Lab

Pathology & Laboratory Medicine - Whether the level of activation induced cytidine deaminase (AID) activity in Follicular lymphoma (FL) tumors can be used as a prognostic factor to identify FL patients who are more likely to transform into Diffuse Large B-cell lymphoma (DLBCL)

Laura Calvi, M.D.

Laura Calvi, M.D.

Assistant Professor

Calvi Lab

Medicine - Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow

Joe Chakkalakal, Ph.D.

Joe Chakkalakal, Ph.D.

Assistant Professor

Chakkalakal Lab

Orthopaedics - Satellite cells are a population of resident stem cells that serve as a renewable source of progenitors for the growth and regeneration of skeletal muscle.

Chawnshang Chang, Ph.D.

Chawnshang Chang, Ph.D.

George Hoyt Whipple Professorship of Pathology
Professor

Chang Lab

George H. Whipple Laboratory for Cancer Research

Pathology & Laboratory Medicine - Androgen Receptor: Molecular Mechanisms, in vivo function and clinic application

Jan Czyzyk, M.D.

Jan Czyzyk, M.D.

Assistant Professor

Czyzyk Lab

Pathology & Laboratory Medicine - Autoantibodies and diabetes

Alison Elder, Ph.D.

Alison Elder, Ph.D.

Associate Professor

Elder Lab

Environmental Medicine - Defining the impact of inhaled ambient and workplace nano-/ultrafine particle-containing aerosols on the lung, cardiovascular system, and central nervous system, and defining the toxicological properties of the particles that are associated with a response.

Roman Eliseev, M.D., Ph.D.

Roman Eliseev, M.D., Ph.D.

Assistant Professor

Eliseev Lab

Orthopaedics - Role of mitochondria in regulation of apoptosis and differentiation in cancer cells and in normal stem cells

Fabeha Fazal, Ph.D.

Fabeha Fazal, Ph.D.

Assistant Professor
Pediatrics - Understanding the role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis, especially in the settings of acute and chronic lung injury

Lin Gan, Ph.D.

Lin Gan, Ph.D.

Professor

Gan Lab

Ophthalmology - Development and degenerative diseases of sensory neurons, gene regulation

Steve Georas, M.D.

Steve Georas, M.D.

Professor

Georas Lab

Medicine - Defining the role of environmental exposures on innate and adaptive immunity in asthma and other chronic lung diseases, with an emphasis on how particulate matter and endocrine disruptors act as risk factors.

Stephen Hammes, M.D., Ph.D.

Stephen Hammes, M.D., Ph.D.

Professor

Hammes Lab

Medicine - How steroids regulate reproduction and hormone-dependent cancers

Denise Hocking, Ph.D.

Denise Hocking, Ph.D.

Associate Professor

Hocking Lab

Pharmacology & Physiology - Regulation of cell behavior by the extracellular matrix

Wei Hsu, PhD

Wei Hsu, PhD

Professor

Hsu Lab

Biomedical Genetics - Cellular Signaling in Neural Development and Disease

Jennifer Hunter, Ph.D.

Jennifer Hunter, Ph.D.

Assistant Professor

Hunter Lab

Ophthalmology - Mechanisms of light-induced retinal damage and development of non-invasive fluorescence imaging techniques

Gail Johnson, Ph.D

Gail Johnson, Ph.D

Professor

Johnson Lab

Anesthesiology - Defining molecular mechanisms of neurodegeneration, and regulation of cell death and survival processes in the central nervous system.

Jennifer Jonason, Ph.D.

Jennifer Jonason, Ph.D.

Assistant Professor

Jonason Lab

Orthopaedics - Skeletal development and osteoarthritis

Kirsi Järvinen-Seppo, M.D., Ph.D.

Kirsi Järvinen-Seppo, M.D., Ph.D.

Associate Professor

Järvinen-Seppo Lab

Pediatrics - Food allergies disorders, caused by milk, eggs and peanuts.

Amy Kiernan, Ph.D.

Amy Kiernan, Ph.D.

Associate Professor

Kiernan Lab

Ophthalmology - Molecular development of the inner ear; regeneration; congenital deafness and vestibular dysfunction

Yi-Fen Lee, Ph.D.

Yi-Fen Lee, Ph.D.

Associate Professor

Yi Fen Lee Lab

Urology - Vitamin D Receptor and TR4 Nuclear Receptor

Richard Libby, Ph.D.

Richard Libby, Ph.D.

Associate Professor

Libby Lab

Ophthalmology - Neurobiology of glaucoma; specifically the death of retinal ganglion cells (RGCs), the output neurons of the retina.

Alayna Loiselle, Ph.D.

Alayna Loiselle, Ph.D.

Assistant Professor

Loiselle Lab

Orthopaedics - cellular and molecular mechanisms of musculoskeletal tissue regeneration and pathology

Anne Luebke, Ph.D.

Anne Luebke, Ph.D.

Associate Professor

Luebke Lab

NeuroscienceBiomedical Engineering - Role of cochlear outer hair cells in hearing and hearing loss, at both the molecular and systems levels

Thomas Mariani, Ph.D.

Thomas Mariani, Ph.D.

Associate Professor

Mariani Lab

Pediatrics - Systems Biology of Lung Development and Disease

Margot Mayer-Pröschel, Ph.D.

Margot Mayer-Pröschel, Ph.D.

Associate Professor

Mayer-Pröschel Lab

Biomedical Genetics - Deciphering the impact of nutritional, toxicological, viral, and genetic insults, singly and in combination, on mammalian brain development and disease later in life.

Joseph Miano, Ph.D.

Joseph Miano, Ph.D.

Professor
Associate Professor

Miano Lab

Medicine - Discovery and function of long noncoding RNAs and CArG regulatory elements in mouse and human genomes; genome editing in mice

Robert Mooney, Ph.D.

Robert Mooney, Ph.D.

Professor

Mooney Lab

Pathology & Laboratory Medicine - Bone diseases, particularly osteoporosis and osteoarthritis

Craig Morrell, D.V.M., Ph.D.

Craig Morrell, D.V.M., Ph.D.

Assistant Professor

Morrell Lab

Medicine - Function of Platelets: Hemostastis/Thrombosis and Immune Regulatory Function

Maiken Nedergaard, M.D., DMSc

Maiken Nedergaard, M.D., DMSc

Professor

Nedergaard Lab

Neurosurgery - The basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction.

Mark Noble, Ph.D.

Mark Noble, Ph.D.

Professor

Noble Lab

Biomedical Genetics - Discovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.

John Olschowka, Ph.D.

John Olschowka, Ph.D.

Professor
Associate Chair for Education

O'Banion-Olschowka Labs

Neuroscience - Neural-immune interactions

Catherine Ovitt, Ph.D.

Catherine Ovitt, Ph.D.

Associate Professor

Ovitt Lab

Biomedical Genetics - Analysis of Genes Involved in Salivary Gland Function

James Palis, M.D.

James Palis, M.D.

Professor

Palis Lab

Pediatrics - Pediatric Hematology and Oncolog

Archibald Perkins, M.D., Ph.D.

Archibald Perkins, M.D., Ph.D.

Professor

Perkins Lab

Pathology & Laboratory Medicine - Genes that impact the development of leukemias and other human malignancies

Richard Phipps, Ph.D.

Richard Phipps, Ph.D.

Professor

Phipps Lab

Environmental Medicine - Investigating how environmental factors shape diseases involving immune and inflammatory components, including platelets, B cells, and lipid mediators, defining abnormal inflammatory and wound healing responses in the eye and lung, delineating molecular signaling in fibroblasts.

Christoph Pröschel, Ph.D.

Christoph Pröschel, Ph.D.

Associate Professor

Pröschel Lab

Biomedical Genetics - Defining roles of glial progenitor cells and astrocytes as critical modulators in responses to chemical exposure, injury, or stress; discovering how exogenous factors contribute to neurodegenerative diseases; and developing new approaches to treat traumatic injury and neurodegenerative diseases.

J. Edward Puzas, Ph.D.

J. Edward Puzas, Ph.D.

Professor

Puzas Lab

Orthopaedics - Deciphering the molecular signals that govern osteoporosis and arthritis, as well as cellular changes that contribute to difficulties such as the loosening of artificial joints, including defining how environmental toxins such as lead, play a role in bone and joint diseases.

Arshad Rahman, Ph.D.

Arshad Rahman, Ph.D.

Associate Professor

Arshad Rahman Lab

Pediatrics - Determining how exogenous agents change lung microvasculature permeability, leading to pulmonary inflammation.

Irfan Rahman, Ph.D.

Irfan Rahman, Ph.D.

Professor

Irfan Rahman Lab

Environmental Medicine - Defining effects of inhaled environmental tobacco smoke, e-cigarettes, flavoring chemicals, and water pipe smoke toxicants on mitochondrial function, exosomes, and epigenetic chromatin modifiers in lung cell senescence, oxidative stress, and inflammation.

Jesse Schallek, Ph.D.

Jesse Schallek, Ph.D.

Assistant Professor

Advanced Retinal Imaging Alliance

Ophthalmology - Examining the role of blood flow regulation and capillary level neurovascular coupling in the central nervous system

Edward Schwarz, Ph.D.

Edward Schwarz, Ph.D.

Professor

Schwarz Lab

Orthopaedics - Novel therapies for musculoskeletal diseases

Michael Sellix, Ph.D.

Michael Sellix, Ph.D.

Assistant Professor

Sellix Lab

Medicine - <q>Clock-controlled</q> gene expression in the ovary

Patricia Sime, M.D.

Patricia Sime, M.D.

Professor

Sime Lab

Medicine - Conducting clinical and translational toxicology research focusing on the lung, from studies of silica and radiation in lung fibrosis, to the effects of biomass and cigarette smoke exposure on lung inflammation and resolution pathways, to identifying key pathophysiologic pathways and developing novel therapeutics for lung inflammation and fibrosis.

Patricia Simpson-Haidaris, Ph.D.

Patricia Simpson-Haidaris, Ph.D.

Associate Professor
Medicine - Role of Fibrinogen in Acute Inflammation.

Ruchira Singh, Ph.D.

Ruchira Singh, Ph.D.

Assistant Professor

Singh Lab

Ophthalmology - Cellular and molecular mechanisms of retinal and neurodegenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems

Harold Smith, Ph.D.

Harold Smith, Ph.D.

Professor

Smith Lab

Biochemistry & Biophysics - RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.

Jane Sottile, Ph.D.

Jane Sottile, Ph.D.

Associate Professor

Sottile Lab

Medicine - Mechanisms That Control Extracellular Matrix Remodeling

Laurie Steiner, M.D.

Laurie Steiner, M.D.

Assistant Professor
Professor

Steiner Lab

PediatricsMedicine - Pediatric Biomedical Research

Juilee Thakar, Ph.D.

Juilee Thakar, Ph.D.

Assistant Professor

Thakar Lab

Microbiology & Immunology - Identification of immune signatures and characterization of dynamics of immune responses by using systems biology approaches.

David Topham, Ph.D.

David Topham, Ph.D.

Professor

Topham Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology - Conducting clinical and translational research on respiratory pathogens, immunity, and infectious disease, including the study of environmental factors that affect immune responses to influenza and vaccination, seeking new approaches to enhance immunity, reduce pathology, and prevent disease.

Hugh Xia, M.Sc., Ph.D.

Hugh Xia, M.Sc., Ph.D.

Associate Professor

Xia Lab

Pharmacology & Physiology - Investigating the role of environmental toxins such as arsenic on the protein phosphatase-1, a regulator of synaptic plasticity and cognition.

Lianping Xing, B.Med., Ph.D.

Lianping Xing, B.Med., Ph.D.

Associate Professor

Xing Lab

Pathology & Laboratory Medicine - Regulation of bone cell function in inflammatory bone loss

Chen Yan, Ph.D.

Chen Yan, Ph.D.

Associate Professor

Yan Lab

Medicine - Regulation and Function of Cyclic Nucleotide Phosphodiesterases in the Cardiovascular System

Tingting Yang, Ph.D.

Tingting Yang, Ph.D.

Assistant Professor

Yang Lab

Pharmacology & Physiology - Structure and function of calcium-activated chloride channels

Xinping Zhang, B.Med., Ph.D.

Xinping Zhang, B.Med., Ph.D.

Associate Professor

Zhang Lab

Orthopaedics - Skeletal repair and reconstruction

Michael Zuscik, Ph.D.

Michael Zuscik, Ph.D.

Associate Professor

Zuscik Lab

Orthopaedics - Defining the impact of obesity on bone repair, the molecular and cellular impact of chemical substances, including lead and benzo(a)pyrene, elucidating the molecular basis for deleterious effects of cigarette smoke on bone fracture healing, and uncovering basic signaling pathways involved with Pb-induced bone loss.