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Faculty

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Affiliated Faculty

Brian Altman, Ph.D.
Brian Altman, Ph.D.

Altman Lab

Biomedical Genetics
Research Interest:

Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism. 


Jennifer Anolik, M.D., Ph.D.
Jennifer Anolik, M.D., Ph.D.

Anolik Lab

Pathology & Laboratory Medicine
Microbiology & Immunology
Medicine
Research Interest: The role of B cells in the pathophysiology of human systemic lupus and rheumatoid arthritis and the study of new immuno-modulatory treatments

Jeevisha Bajaj, Ph.D.
Jeevisha Bajaj, Ph.D.

Bajaj Lab

Biomedical Genetics
Research Interest: Molecular mechanisms of cancer stem cell interactions with tumor microenvironment in disease progression

Lisa Beck, M.D.
Lisa Beck, M.D.

Beck Lab

Dermatology
Medicine
Research Interest: Cutaneous allergic inflammation, Atopic Dermatitis (eczema)

Bradford Berk, M.D., Ph.D.
Bradford Berk, M.D., Ph.D.

Berk Lab

Medicine
Pharmacology & Physiology
Neurology
Research Interest: Signaling transduction mechanisms in the vascular system

Rajnish Bharadwaj, M.B.B.S., Ph.D.
Rajnish Bharadwaj, M.B.B.S., Ph.D.

Bharadwaj Lab

Neuroscience
Pathology & Laboratory Medicine
Research Interest: Lysosomal and mitochondrial dysfunction in neurodegenerative diseases

Matthew Brewer, Ph.D.
Matthew Brewer, Ph.D.

Beck Lab

Brewer Lab

Dermatology
Research Interest:

The intersection between chronic inflammatory skin diseases (such as atopic dermatitis and psoriasis) and the underlying immune environment during times of stimulation (such as vaccination) and disease (both viral and bacterial pathogens).


Paul Brookes, Ph.D.
Paul Brookes, Ph.D.

Brookes Lab

Mitochondrial Research and Innovation Group

Anesthesiology and Perioperative Medicine
Pharmacology & Physiology
Research Interest: Cardioprotection against ischemia-reperfusion (IR) injury. Role of Mitochondria and metabolism in ischemic preconditioning and anesthetic preconditioning.

Laura Calvi, M.D.
Laura Calvi, M.D.

Calvi Lab

Medicine
Pharmacology & Physiology
Neurosurgery
Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow

Chike Cao, Ph.D.
Chike Cao, Ph.D.

Cao Lab

Orthopaedics
Pharmacology & Physiology
Research Interest:

The role of CAv 1, 2 in tendon formation and heterotopic bone (HO) formation


Darren Carpizo, M.D., Ph.D.
Darren Carpizo, M.D., Ph.D.

Carpizo Lab

Surgery
Research Interest: My laboratory studies cancer biology with an emphasis in developmental therapeutics and pancreatic cancer metastasis and dormancy

Kavaljit Chhabra, M.Pharm., Ph.D.
Kavaljit Chhabra, M.Pharm., Ph.D.

Chhabra Lab

Medicine
Pharmacology & Physiology
Research Interest: Molecular basis of glucose sensing in the brain and beta cells

Calvin Cole, Ph.D.
Calvin Cole, Ph.D.

Cole Lab

Surgery
Orthopaedics
Research Interest:

Research Interest: Elucidating the Mechanisms of Disease-related Skeletal Muscle Wasting with the goal of discovering viable therapies that will improve patients’ quality of life, and treatment outcomes related to the underlying pathology.


David Dean, Ph.D.
David Dean, Ph.D.

Dean Lab

Pharmacology & Physiology
Biomedical Engineering
Pediatrics
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease

Thomas Diekwisch, D.M.D., Ph.D.
Thomas Diekwisch, D.M.D., Ph.D.

Diekwisch Lab

Oral and Cranial Facial Sciences
Research Interest:

Our research interests span three areas including epigenetic mechanisms of mitotic cell division, chromatin, heterochromatin, histone variants and modifications;  biomineralization of odontogenic tissues and finally generating tools for engineering and regeneration of complex periodontal tissues.


Alison Elder, Ph.D.
Alison Elder, Ph.D.

Elder Lab

Environmental Medicine
Research Interest: Toxicology of inhaled ultrafine particles (UFPs) on the lung, cardiovascular and central nervous system

Roman Eliseev, M.D., Ph.D.
Roman Eliseev, M.D., Ph.D.

Eliseev Lab

Mitochondrial Research and Innovation Group

Orthopaedics
Pharmacology & Physiology
Research Interest:

Role of Mitochondria in regulation of cell fate in normal stem cells and cancer cells


Fabeha Fazal, Ph.D.
Fabeha Fazal, Ph.D.

Fazal Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis in acute and chronic lung injury

Benjamin Frisch, Ph.D.
Benjamin Frisch, Ph.D.

Frisch Lab

Pathology & Laboratory Medicine
Research Interest: Role of inflammatory mediators in bone marrow microenvironmental dysfunction during hematologic malignancies

Steve Georas, M.D.
Steve Georas, M.D.

Georas Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology
Environmental Medicine
Medicine
Research Interest:

Defining molecular mechanisms for respiratory-virus induced epithelial barrier dysfunction; exploring the use of oscillometry in the diagnosis and management of airways disorders; and determining how race neutral PFT interpretation strategies impact the utility of spirometry


Scott Gerber, Ph.D.
Scott Gerber, Ph.D.

Gerber Lab

Center for Tumor Immunology Research

Microbiology & Immunology
Surgery
Research Interest: The Gerber lab studies tumor immunology with a focus on harnessing the immune system to recognize and kill cancerous cells utilizing an immunotherapeutic approach to enhance the efficacy of chemo/radiotherapies to control or even cure both primary and metastatic malignancies.

Angela Glading, Ph.D.
Angela Glading, Ph.D.

Glading Lab

Pharmacology & Physiology
Biomedical Engineering
Research Interest: Role of cell-cell contact in regulating cellular function in both the normal and disease state

Lauren Hablitz, Ph.D.
Lauren Hablitz, Ph.D.

Hablitz Lab

Neurology
Research Interest:

Basic biological mechanisms of circadian synchrony and entrainment in health and disease. Understanding how circadian rhythms and sleep can enhance glymphatic, neuronal, and cerebrovascular function.


Stephen Hammes, M.D., Ph.D.
Stephen Hammes, M.D., Ph.D.

Hammes Lab

Medicine
Pharmacology & Physiology
Research Interest: Androgen Effects on Reproduction and Cancer

J. Christopher Holt, Ph.D.
J. Christopher Holt, Ph.D.

Holt Lab

Neuroscience
Otolaryngology
Research Interest:

Synaptic pharmaco-physiology of vestibular efferent-afferent interactions


Kirsi Järvinen-Seppo, M.D., Ph.D.
Kirsi Järvinen-Seppo, M.D., Ph.D.

Järvinen-Seppo Lab

Microbiology & Immunology
Pediatrics
Research Interest:

Food allergies disorders, caused by milk, eggs and peanuts.


Amy Kiernan, Ph.D.
Amy Kiernan, Ph.D.

Kiernan Lab

Ophthalmology
Flaum Eye Institute
Biomedical Genetics
Research Interest: Molecular development of the eye and inner ear; anterior segment dysgenesis (ASD) and developmental glaucoma; congenital deafness and vestibular dysfunction

Benjamin Korman, M.D.
Benjamin Korman, M.D.

Korman Lab

Medicine
Research Interest: Cellular and molecular processes leading to scleroderma (fibrosis)

Yi-Fen Lee, Ph.D.
Yi-Fen Lee, Ph.D.

Yi-Fen Lee Lab

Pathology & Laboratory Medicine
Urology
Research Interest: Extracellular vesicles (Evs), Exosomes, for their roles in cancer development, progression and response to treatment in Urology cancers.

Richard Libby, Ph.D.
Richard Libby, Ph.D.

Libby Lab

Biomedical Genetics
Flaum Eye Institute
Ophthalmology
Research Interest: Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death.

Alayna Loiselle, Ph.D.
Alayna Loiselle, Ph.D.

Loiselle Lab

Orthopaedics
Research Interest:

Musculoskeletal tissue regeneration


Xianghong Luan, MD
Xianghong Luan, MD
Oral and Cranial Facial Sciences
Research Interest:

Research in our laboratory focuses on materials design for tissue regeneration. Other areas of interest include microRNAs and the amelogenin extracellular matrix molecule.


Thomas Mariani, Ph.D.
Thomas Mariani, Ph.D.

Mariani Lab

Biomedical Genetics
Medicine
Environmental Medicine
Pediatrics
Research Interest:

Genetic mechanisms of susceptibility to congenital and infectious lung diseases, focusing on developmental antecedents and the influence of environmental factors.


Matthew McGraw, M.D.
Matthew McGraw, M.D.

McGraw Lab

Pediatrics
Research Interest: Epithelial injury and abnormal repair in pediatric and adult lung disease

Helene McMurray, Ph.D.
Helene McMurray, Ph.D.
Director

McMurray Lab

Pathology & Laboratory Medicine
Research Interest: Analysis of gene regulatory networks in cancer; role of immunogenetics in transplant

Craig Morrell, D.V.M., Ph.D.
Craig Morrell, D.V.M., Ph.D.

Morrell Lab

Medicine
Microbiology & Immunology
Pathology & Laboratory Medicine
Research Interest: Platelet functions in hemostasis/thrombosis and vascular inflammation. Platelet driven immune responses.

Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest:

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.


Gowrishankar Muthukrishnan, Ph.D.
Gowrishankar Muthukrishnan, Ph.D.

Muthukrishnan Lab

Orthopaedics
Microbiology & Immunology
Research Interest:

Understanding host-pathogen interactions and the osteoimmunology of orthopaedic infections


Maiken Nedergaard, M.D., DMSc
Maiken Nedergaard, M.D., DMSc

Nedergaard Lab

Neurosurgery
Biomedical Engineering
Neurology
Neuroscience
Research Interest: The basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction.

Anne Nichols, Ph.D.
Anne Nichols, Ph.D.

Loiselle Lab

Nichols Lab

Research Interest:

The Identity, Function, and Fate of Epitenon-Derived Progenitor Cells in Tendon Healing


Mark Noble, Ph.D.
Mark Noble, Ph.D.

Noble Lab

Biomedical Genetics
Neuroscience
Research Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury.

James Palis, M.D.
James Palis, M.D.

Palis Lab

Biomedical Genetics
Pediatrics
Research Interest: Cellular and Molecular events underlying the ontogeny of the hematopoietic system.

Jinjiang Pang, B.Med., Ph.D.
Jinjiang Pang, B.Med., Ph.D.

Pang Lab

Medicine
Research Interest: Molecular mechanisms of angiogenesis and vascular remodeling in physiological and pathological conditions.

Hae-Ryung Park, Ph.D.
Hae-Ryung Park, Ph.D.

Park Lab

Environmental Medicine
Research Interest:

Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism of the targets and neurological diseases. Explore novel roles of extracellular vesicles (EV) in receptor signaling and cell communication. Identify EV-encapsulated biomolecules released by the placenta in response to environmental perturbation. Explore the roles of placenta-derived EVs on neurodevelopment or neurodegeneration


Archibald Perkins, M.D., Ph.D.
Archibald Perkins, M.D., Ph.D.

Perkins / Zhang Lab

Pathology & Laboratory Medicine
Research Interest: Genetic mechanisms in acute myeloid leukemia and myelodysplastic syndrome with focus on the zinc finger oncoprotein EVI1

Christoph Pröschel, Ph.D.
Christoph Pröschel, Ph.D.

Pröschel Lab

Biomedical Genetics
Research Interest:

Using primarily human pluripotent stem cell models, we examine astrocyte development in normal and pathological conditions, the role of astrocytes in modulating response to injury or stress, the role of altered RNA processing and translation in neural development, and the utility of glial precursor cells and their astrocytic progeny for cell transplantation therapy.


Homaira Rahimi, M.D.
Homaira Rahimi, M.D.

Rahimi Lab

Schwarz Lab

Pediatrics
Research Interest: Juvenile Idiopathic arthritis. Imaging of lymph nodes as a martyr for arthritic flare in RA, lymphangiogenesis in Arthritic flare in murine model of erosive arthritis.

Arshad Rahman, Ph.D.
Arshad Rahman, Ph.D.

Arshad Rahman Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.

Irfan Rahman, Ph.D.
Irfan Rahman, Ph.D.

Irfan Rahman Lab

Environmental Medicine
Medicine
Public Health Sciences
Dentistry
Research Interest: Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants.

Regina Rowe, M.D., Ph.D.
Regina Rowe, M.D., Ph.D.

Rowe Lab

Pediatrics
Research Interest:

Mechanisms of how allergic inflammation impacts innate immune cell antiviral responses.


Edward Schwarz, Ph.D.
Edward Schwarz, Ph.D.

Schwarz Lab

Pathology & Laboratory Medicine
Urology
Medicine
Biomedical Engineering
Microbiology & Immunology
Orthopaedics
Research Interest: Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants

Ruchira Singh, Ph.D.
Ruchira Singh, Ph.D.

Singh Lab

Flaum Eye Institute
Biomedical Genetics
Ophthalmology
Research Interest:

Using patient-derived human induced pluripotent stem cells (hiPSCs) to study the molecular mechanism of specific retinal and neurological diseases and applying that knowledge to pharmacologically target certain retinal disorders in patient-derived cells.


Eric Small, Ph.D.
Eric Small, Ph.D.

Small Lab

Medicine
Pharmacology & Physiology
Biomedical Engineering
Research Interest:

To better understand the mechanisms that control cell identity and lineage commitment by studying the transcriptional regulation and function of cardiac tissue-restricted genes


Laurie Steiner, M.D.
Laurie Steiner, M.D.

Steiner Lab

Pediatrics
Medicine
Research Interest:

Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.


Martha Susiarjo, Ph.D.
Martha Susiarjo, Ph.D.

Susiarjo Lab

Environmental Medicine
Research Interest:

Our research program focuses on mechanisms underlying gene environment interaction in pregnancy. We are interested in elucidating how environmental factors influence epigenetic regulation of developmental-relevant genes including imprinted genes, and how exposure modulates maternal-fetal health.


Michael Telias, Ph.D.
Michael Telias, Ph.D.

Telias Lab

Ophthalmology
Flaum Eye Institute
Neuroscience
Research Interest:

Retinal degeneration and maladaptive plasticity in inner retinal circuits.


Juilee Thakar, Ph.D.
Juilee Thakar, Ph.D.

Thakar Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology
Research Interest: Systems approach utilizing bioinformatics, and dynamic modeling tools to study immune response to infections and vaccination.

Paula Vertino, Ph.D.
Paula Vertino, Ph.D.

Vertino Lab

Biomedical Genetics
Research Interest: Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic intervention

Collynn Woeller, Ph.D.
Collynn Woeller, Ph.D.

Woeller Lab

Flaum Eye Institute
Environmental Medicine
Ophthalmology
Research Interest: Understanding the key molecular and cellular pathways involved in eye disease, with a particular focus on Thyroid Eye Disease (TED)

Terry Wright, Ph.D.
Terry Wright, Ph.D.
Pediatrics
Microbiology & Immunology
Research Interest: Immune response and Pathogenesis of lung injury and related pulmonary inflammation

Chia-Lung Wu, Ph.D.
Chia-Lung Wu, Ph.D.

Chia-Lung Wu Lab

Orthopaedics
Research Interest: Identifying the molecular mechanisms by which genetic and epigenetic regulators modulate development, homeostasis and disease progression of musculoskeletal tissues, with a particular focus on cartilage and bone.

Lianping Xing, B.Med., Ph.D.
Lianping Xing, B.Med., Ph.D.

Xing Lab

Pathology & Laboratory Medicine
Research Interest: Regulation of bone cell function in inflammatory bone loss

Chen Yan, Ph.D.
Chen Yan, Ph.D.

Yan Lab

Medicine
Research Interest: Regulation and Function of Cyclic Nucleotide Phosphodiesterases in the Cardiovascular System

Peng Yao, Ph.D.
Peng Yao, Ph.D.

Yao Lab

Mitochondrial Research and Innovation Group

Biochemistry & Biophysics
Medicine
Research Interest:

Pathophysiological function and molecular mechanism of new non-coding RNAs and RNA-binding proteins and translational control in cardiac system and cardiovascular disease


Zhenqiang Yao, B.Med., Ph.D.
Zhenqiang Yao, B.Med., Ph.D.

Yao - Zhenqiang Lab

Pathology & Laboratory Medicine
Dentistry
Research Interest:

NF-kB signaling pathway, Apoptosis signaling pathway, Bone metabolism, and Osteoimmunology.


Shu-Yuan Yeh, Ph.D.
Shu-Yuan Yeh, Ph.D.

George H. Whipple Laboratory for Cancer Research

Shu-Yuan Yeh Lab

Urology
Pathology & Laboratory Medicine
Research Interest: Role of the estrogen receptor (ER) and androgen receptor (AR) in urological diseases, including prostate cancer, bladder cancer, benign prostatic hyperplasia (BPH) and male fertility.

Xinping Zhang, B.Med., Ph.D.
Xinping Zhang, B.Med., Ph.D.

Zhang Lab

Orthopaedics
Research Interest: Molecular mechanisms of skeletal repair in bone loss due to traumatic injury, tumor and bone graft.