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Research

Cancer Biology

About

 

The Cell Biology of Disease program has research groups investigating a wide variety of topics in cancer biology. The James P. Wilmot Cancer Institute is leading efforts in cancer biology at the University and includes faculty from many different clinical and basic science departments.  Areas under current investigation include radiation biology, solid tumor biology, blood cancers, cancer biomarkers, cancer susceptibility factors, cancer genomics, cancer immunology, and cancer therapeutics.

Centers and Groups

Faculty

Cardiovascular Disease

About

The Cell Biology of Disease program has research groups studying a vast array of disorders affecting the cardiovascular system. These groups use state of the art cell biological and clinical tools to investigate heart and blood vessel function and disease states, with particular focus on determining the molecular pathways controlling cardiac and vessel disease, developing new diagnostic tools for early detection of cardiovascular disease, and using regenerative biology to speed recovery.

Centers and Groups

Cardiovascular Research Institute (CVRI)

Faculty

Infectious Disease, Hematology and Autoimmune Disease

About

The Cell Biology of Disease program has research groups investigating a variety of topics related to inflammation, blood borne disease, and immune system dysfunction. These groups work in numerous departments and centers throughout the University of Rochester. Current areas being actively studied include HIV/AIDS, leukemia, cystic fibrosis, vaccine development, bacterial and viral infections, allergies, and autoimmune disorders.

Centers and Groups

Faculty

Lung Biology and Disease

About

Investigators in the Cell Biology of Disease program are interested in the underlying cell biology and physiology of lung development and disease. There are active research programs probing developmental lung disorders, complications following surgery, the effects of environmental exposure on lung function, and age related lung disease. Research topics include lung cancer, neonatal lung disease that results from premature birth, chronic obstructive pulmonary disease (COPD), infection, environmental exposure of airborne toxins, asthma, and lung scarring.

Centers and Groups

Example Faculty

Metabolic Disorders, Reproduction and Physiology

About

Many of our Cell Biology of Disease researchers are focused on disorders of metabolic processes and basic cellular physiology. Work in these areas include extensive efforts studying diabetes, diabetic retinopathy, cellular stress, mitochondrial biology and disorders, fertility and obesity.

Centers and Groups

Faculty

Orthopaedic and Musculoskeletal Research

About

The Cell Biology of Disease program faculty study various aspects of the musculoskeletal system. Many of these faculty are members of the URMC Center for Musculoskeletal Research, one the nation’s top NIH funded centers for orthopaedic research. Major research areas include bone biology and disease, cartilage biology and arthritis, musculoskeletal stem cell biology, musculoskeletal repair and maintenance, musculoskeletal development, and bone cancer biology.

Centers and Groups

Faculty

Neurology and Neurodegenerative Disease

About

The University of Rochester has researchers investigating many different neurological diseases. These groups, which span over 10 departments and multiple centers, study both neurological disease (e.g. Alzheimer’s disease, stroke, spinal cord injury, psychiatric disorders) and fundamental biology of the brain that contributes to disease onset and progression (e.g. glial biology, neuroinflammation, glymphatic system). Furthermore, neurodegenerative diseases are studied using a variety of models systems, and in patients.  

Centers and Groups

Faculty

Pediatric Disease, Developmental Biology, and Aging

About

The Cell Biology of Disease program faculty have a strong interest in pediatric disease, developmental biology, and aging. Research areas include studying developmental and age related diseases in most organ systems, including lungs, heart, brain, sensory systems, and bone. Furthermore, many groups collaborate with investigations studying the basic cell biology that controls normal development and aging.

Centers and Groups

Faculty

Regenerative Medicine and Stem Cells

About

The Cell Biology of Disease faculty study various aspects of regenerative biology as it applies to a wide range of diseases. Research groups use cell biological tools to induce recovery after injury and disease, including stem cells, viral mediated gene transfer and cell based therapeutic approaches.  

Centers and Groups

Faculty

Sensory Systems Biology and Disease

About

The University of Rochester has active research programs investigating the biology underlying sensory disorders. Using a variety of advanced cell biological techniques, these groups study low vision and blindness, hearing and balance disorders, and oral disease. There is a wide spectrum of research in these areas, from developmental disorders affecting children to age-related sensory loss.  

Centers and Groups

Faculty