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Affiliated Faculty

Olga Astapova, MD, PhD
Olga Astapova, MD, PhD

Astapova Lab

Medicine
Research Interest:

Roles of nuclear hormone receptors in metabolism and reproduction, particularly metabolic syndrome and polycystic ovary syndrome


Not accepting students at this time.
Danielle Benoit, Ph.D.
Danielle Benoit, Ph.D.

Benoit Lab

Chemical Engineering
Biomedical Engineering
Research Interest:

Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments


Mentor for Toxicology Ph.D. Program
Laura Calvi, M.D.
Laura Calvi, M.D.

Calvi Lab

Medicine
Pharmacology & Physiology
Neurosurgery
Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow

Mentor for Toxicology Ph.D. Program
Deborah Cory-Slechta, Ph.D.
Deborah Cory-Slechta, Ph.D.

Cory-Slechta Lab

Public Health Sciences
Environmental Medicine
Research Interest: Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.

Mentor for Toxicology Ph.D. Program
Lisa DeLouise, Ph.D., M.P.D.
Lisa DeLouise, Ph.D., M.P.D.

DeLouise Lab

Biomedical Engineering
Dermatology
Electrical & Computer Engineering
Research Interest: Understanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.

Mentor for Toxicology Ph.D. Program
David Dean, Ph.D.
David Dean, Ph.D.

Dean Lab

Pharmacology & Physiology
Biomedical Engineering
Pediatrics
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease

Mentor for Toxicology Ph.D. Program
Alison Elder, Ph.D.
Alison Elder, Ph.D.

Elder Lab

Environmental Medicine
Research Interest: Toxicology of inhaled ultrafine particles (UFPs) on the lung, cardiovascular and central nervous system

Mentor for Toxicology Ph.D. Program
Fabeha Fazal, Ph.D.
Fabeha Fazal, Ph.D.

Fazal Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis in acute and chronic lung injury

Mentor for Toxicology Ph.D. Program
Jacob Finkelstein, Ph.D.
Jacob Finkelstein, Ph.D.

Finkelstein Lab

Environmental Medicine
Radiation Oncology
Pediatrics
Research Interest: Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.

Mentor for Toxicology Ph.D. Program
Steve Georas, M.D.
Steve Georas, M.D.

Georas Lab

Microbiology & Immunology
Environmental Medicine
Medicine
Research Interest: Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system

Mentor for Toxicology Ph.D. Program
Scott Gerber, Ph.D.
Scott Gerber, Ph.D.

Gerber Lab

Center for Tumor Immunology Research

Microbiology & Immunology
Surgery
Research Interest: The Gerber lab studies tumor immunology with a focus on harnessing the immune system to recognize and kill cancerous cells utilizing an immunotherapeutic approach to enhance the efficacy of chemo/radiotherapies to control or even cure both primary and metastatic malignancies.

Mentor for Toxicology Ph.D. Program
Gail Johnson, Ph.D
Gail Johnson, Ph.D

Gail Johnson Lab

Pharmacology & Physiology
Anesthesiology and Perioperative Medicine
Research Interest: Molecular mechanisms of Neurodegeneration

Mentor for Toxicology Ph.D. Program
Todd Jusko, Ph.D.
Todd Jusko, Ph.D.

Rochester Environment and Child Health (REACH) Laboratory

Public Health Sciences
Pediatrics
Environmental Medicine
Research Interest: Environmental and Maternal and Child Health Epidemiology: Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.

Mentor for Toxicology Ph.D. Program
Matthew Kottmann, M.D.
Matthew Kottmann, M.D.

Kottmann Lab

Medicine
Research Interest: Investigating how novel receptor-based therapeutics modify cytokine production to mitigate lung injury and fibrosis

Mentor for Toxicology Ph.D. Program
B. Paige Lawrence, Ph.D.
B. Paige Lawrence, Ph.D.
Director

Lawrence Lab

Environmental Medicine
Microbiology & Immunology
Research Interest: Influence of environmental factors on the development and function of the immune system

Mentor for Toxicology Ph.D. Program
Xin Li, Ph.D.
Xin Li, Ph.D.

Li Lab

Biochemistry & Biophysics
Research Interest: Epigenetic inheritance, small silencing non-coding RNAs, translational control, lead toxicity, and comparative genomics.

Mentor for Toxicology Ph.D. Program
Ania Majewska, Ph.D.
Ania Majewska, Ph.D.

Majewska Lab

Neuroscience
Research Interest: Glia-neuron interactions during synaptic plasticity in health and disease

Mentor for Toxicology Ph.D. Program
Margot Mayer-Pröschel, Ph.D.
Margot Mayer-Pröschel, Ph.D.

Mayer-Pröschel Lab

Neuroscience
Biomedical Genetics
Research Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

Mentor for Toxicology Ph.D. Program
Richard Miller, M.D.
Richard Miller, M.D.

Richard Miller Lab

Environmental Medicine
Pathology & Laboratory Medicine
Obstetrics & Gynecology
Research Interest: Determining the impact of maternal stress and other maternal factors on the birth outcomes and in the children.

Mentor for Toxicology Ph.D. Program
Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest: The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.

Mentor for Toxicology Ph.D. Program
Mark Noble, Ph.D.
Mark Noble, Ph.D.

Noble Lab

Biomedical Genetics
Neuroscience
Research Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury.

Mentor for Toxicology Ph.D. Program
M. Kerry O'Banion, M.D., Ph.D.
M. Kerry O'Banion, M.D., Ph.D.

O'Banion-Olschowka Labs

Neuroscience
Research Interest: Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure

Mentor for Toxicology Ph.D. Program
Michael O'Reilly, Ph.D.
Michael O'Reilly, Ph.D.

O'Reilly Lab

Pediatrics
Environmental Medicine
Research Interest: Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.

Mentor for Toxicology Ph.D. Program
Hae-Ryung Park, Ph.D.
Hae-Ryung Park, Ph.D.

Park Lab

Environmental Medicine
Research Interest: Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism of the targets and neurological diseases. Explore novel roles of extracellular vesicles (EV) in receptor signaling and cell communication. Identify EV-encapsulated biomolecules released by the placenta in response to environmental perturbation. Explore the roles of placenta-derived EVs on neurodevelopment or neurodegeneration

Mentor for Toxicology Ph.D. Program
Gloria Pryhuber, M.D.
Gloria Pryhuber, M.D.

Pryhuber Lab

Pediatrics
Environmental Medicine
Research Interest: Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.

Mentor for Toxicology Ph.D. Program
Christoph Pröschel, Ph.D.
Christoph Pröschel, Ph.D.

Pröschel Lab

Biomedical Genetics
Research Interest: Glial progenitor cells and role of astrocytes as critical modulators in CNS disease and repair

Mentor for Toxicology Ph.D. Program
J. Edward Puzas, Ph.D.
J. Edward Puzas, Ph.D.

Puzas Lab

Orthopaedics
Environmental Medicine
Biomedical Engineering
Research Interest: Molecular signals that govern osteoporosis and arthritis

Mentor for Toxicology Ph.D. Program
Arshad Rahman, Ph.D.
Arshad Rahman, Ph.D.

Arshad Rahman Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.

Mentor for Toxicology Ph.D. Program
Irfan Rahman, Ph.D.
Irfan Rahman, Ph.D.

Irfan Rahman Lab

Environmental Medicine
Medicine
Public Health Sciences
Dentistry
Research Interest: Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants.

Mentor for Toxicology Ph.D. Program
Matthew Rand, Ph.D.
Matthew Rand, Ph.D.

Rand Lab

Environmental Medicine
Research Interest: Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.

Mentor for Toxicology Ph.D. Program
David Rich, Sc.D., M.P.H.
David Rich, Sc.D., M.P.H.

Rich Lab

Environmental Medicine
Public Health Sciences
Research Interest: Environmental, Cardiovascular, and Maternal and Child Health Epidemiology: Examining associations between air pollution and cardiopulmonary and pregnancy outcomes, examining mechanisms of such cardiopulmonary and pregnancy responses, and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposure.

Mentor for Toxicology Ph.D. Program
Jacques Robert, Ph.D.
Jacques Robert, Ph.D.

Robert Lab

Microbiology & Immunology
Environmental Medicine
Research Interest: Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology

Mentor for Toxicology Ph.D. Program
Marissa Sobolewski, Ph.D.
Marissa Sobolewski, Ph.D.

Sobolewski Lab

Environmental Medicine
Research Interest: Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.

Mentor for Toxicology Ph.D. Program
Martha Susiarjo, Ph.D.
Martha Susiarjo, Ph.D.

Susiarjo Lab

Environmental Medicine
Research Interest: Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.

Mentor for Toxicology Ph.D. Program
David Topham, Ph.D.
David Topham, Ph.D.

Program for Advanced Immune Bioimaging

Topham Lab

Microbiology & Immunology
Research Interest: Multiple roles of virus-specific Band T cells in determining the outcome of viral infection of the respiratory tract. Long term protective effect of immunological mechanisms.

Mentor for Toxicology Ph.D. Program
Jacqueline Williams, Ph.D.
Jacqueline Williams, Ph.D.

Jacqueline Williams Lab

Environmental Medicine
Radiation Oncology
Research Interest: Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.

Mentor for Toxicology Ph.D. Program
Houhui Xia, M.Sc., Ph.D.
Houhui Xia, M.Sc., Ph.D.

Xia Lab

Pharmacology & Physiology
Neuroscience
Research Interest: Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health

Mentor for Toxicology Ph.D. Program
Edwin van Wijngaarden, Ph.D., M.Sc.
Edwin van Wijngaarden, Ph.D., M.Sc.

VanWijngaarden Lab

Epidemiology
Public Health Sciences
Environmental Medicine
Research Interest: Environmental and Neurologic Epidemiology: Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.

Mentor for Toxicology Ph.D. Program