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Affiliated Faculty

Jennifer Anolik, M.D., Ph.D.
Jennifer Anolik, M.D., Ph.D.

Anolik Lab

Pathology & Laboratory Medicine
Microbiology & Immunology
Medicine
Research Interest: The role of B cells in the pathophysiology of human systemic lupus and rheumatoid arthritis and the study of new immuno-modulatory treatments

Olga Astapova, M.D., Ph.D.
Olga Astapova, M.D., Ph.D.

Astapova Lab

Medicine
Research Interest:

Mechanisms of androgen actions in the ovary


Danielle Benoit, Ph.D.
Danielle Benoit, Ph.D.

Benoit Lab

Chemical Engineering
Biomedical Engineering
Research Interest:

Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments


Laura Calvi, M.D.
Laura Calvi, M.D.

Calvi Lab

Medicine
Pharmacology & Physiology
Neurosurgery
Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow

Deborah Cory-Slechta, Ph.D.
Deborah Cory-Slechta, Ph.D.

Cory-Slechta Lab

Public Health Sciences
Environmental Medicine
Neuroscience
Research Interest: Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.

Lisa DeLouise, Ph.D., M.P.D.
Lisa DeLouise, Ph.D., M.P.D.

DeLouise Lab

Biomedical Engineering
Dermatology
Electrical & Computer Engineering
Research Interest: Understanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.

David Dean, Ph.D.
David Dean, Ph.D.

Dean Lab

Pharmacology & Physiology
Biomedical Engineering
Pediatrics
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease

Alison Elder, Ph.D.
Alison Elder, Ph.D.

Elder Lab

Environmental Medicine
Research Interest: Toxicology of inhaled ultrafine particles (UFPs) on the lung, cardiovascular and central nervous system

Fabeha Fazal, Ph.D.
Fabeha Fazal, Ph.D.

Fazal Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis in acute and chronic lung injury

Jacob Finkelstein, Ph.D.
Jacob Finkelstein, Ph.D.

Finkelstein Lab

Environmental Medicine
Radiation Oncology
Pediatrics
Research Interest: Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.

Steve Georas, M.D.
Steve Georas, M.D.

Georas Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology
Environmental Medicine
Medicine
Research Interest: Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system

Todd Jusko, Ph.D.
Todd Jusko, Ph.D.

Rochester Environment and Child Health (REACH) Laboratory

Public Health Sciences
Pediatrics
Environmental Medicine
Research Interest: Environmental and Maternal and Child Health Epidemiology: Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.

Matthew Kottmann, M.D.
Matthew Kottmann, M.D.

Kottmann Lab

Medicine
Research Interest: Investigating how novel receptor-based therapeutics modify cytokine production to mitigate lung injury and fibrosis

B. Paige Lawrence, Ph.D.
B. Paige Lawrence, Ph.D.
Director

Lawrence Lab

Environmental Medicine
Microbiology & Immunology
Research Interest: Influence of environmental factors on the development and function of the immune system

Ania Majewska, Ph.D.
Ania Majewska, Ph.D.

Majewska Lab

Neuroscience
Research Interest: Glia-neuron interactions during synaptic plasticity in health and disease

Margot Mayer-Pröschel, Ph.D.
Margot Mayer-Pröschel, Ph.D.

Mayer-Pröschel Lab

Neuroscience
Biomedical Genetics
Research Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest:

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.


Mark Noble, Ph.D.
Mark Noble, Ph.D.

Noble Lab

Biomedical Genetics
Neuroscience
Research Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury.

M. Kerry O'Banion, M.D., Ph.D.
M. Kerry O'Banion, M.D., Ph.D.

O'Banion-Olschowka Labs

Neuroscience
Research Interest: Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure

Thomas O'Connor, Ph.D.
Thomas O'Connor, Ph.D.

Wynne Center for Family Research

Neuroscience
Psychiatry
Obstetrics & Gynecology
Research Interest: The mechanisms by which early stress exposures, including prenatal maternal anxiety and caregiving stress, may persistently shape children's behavioral and biological health

Michael O'Reilly, Ph.D.
Michael O'Reilly, Ph.D.

O'Reilly Lab

Pediatrics
Environmental Medicine
Research Interest: Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.

Hae-Ryung Park, Ph.D.
Hae-Ryung Park, Ph.D.

Park Lab

Environmental Medicine
Research Interest:

Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism of the targets and neurological diseases. Explore novel roles of extracellular vesicles (EV) in receptor signaling and cell communication. Identify EV-encapsulated biomolecules released by the placenta in response to environmental perturbation. Explore the roles of placenta-derived EVs on neurodevelopment or neurodegeneration


Gloria Pryhuber, M.D.
Gloria Pryhuber, M.D.

Pryhuber Lab

Pediatrics
Environmental Medicine
Research Interest: Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.

Christoph Pröschel, Ph.D.
Christoph Pröschel, Ph.D.

Pröschel Lab

Biomedical Genetics
Research Interest:

Astrocyte development in normal and pathological conditions, role of astrocytes in modulating response to injury or stress, utility of glial precursor cells and their astrocytic progeny for cell transplantation therapy


Arshad Rahman, Ph.D.
Arshad Rahman, Ph.D.

Arshad Rahman Lab

Pharmacology & Physiology
Pediatrics
Research Interest: Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.

Irfan Rahman, Ph.D.
Irfan Rahman, Ph.D.

Irfan Rahman Lab

Environmental Medicine
Medicine
Public Health Sciences
Dentistry
Research Interest: Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants.

Matthew Rand, Ph.D.
Matthew Rand, Ph.D.

Rand Lab

Environmental Medicine
Research Interest: Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.

David Rich, Sc.D., M.P.H.
David Rich, Sc.D., M.P.H.

Rich Lab

Environmental Medicine
Public Health Sciences
Research Interest: Environmental, Cardiovascular, and Maternal and Child Health Epidemiology: Examining associations between air pollution and cardiopulmonary and pregnancy outcomes, examining mechanisms of such cardiopulmonary and pregnancy responses, and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposure.

Jacques Robert, Ph.D.
Jacques Robert, Ph.D.

Robert Lab

Microbiology & Immunology
Environmental Medicine
Research Interest: Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology

Regina Rowe, M.D., Ph.D.
Regina Rowe, M.D., Ph.D.

Rowe Lab

Pediatrics
Research Interest:

Mechanisms of how allergic inflammation impacts innate immune cell antiviral responses.


Marissa Sobolewski-Terry, Ph.D.
Marissa Sobolewski-Terry, Ph.D.

Sobolewski Lab

Environmental Medicine
Research Interest:

Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.


Martha Susiarjo, Ph.D.
Martha Susiarjo, Ph.D.

Susiarjo Lab

Environmental Medicine
Research Interest: Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.

David Topham, Ph.D.
David Topham, Ph.D.

Program for Advanced Immune Bioimaging

Topham Lab

Microbiology & Immunology
Research Interest: Multiple roles of virus-specific Band T cells in determining the outcome of viral infection of the respiratory tract. Long term protective effect of immunological mechanisms.

Houhui Xia, M.Sc., Ph.D.
Houhui Xia, M.Sc., Ph.D.

Xia Lab

Pharmacology & Physiology
Neuroscience
Research Interest: Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health

Edwin van Wijngaarden, Ph.D., M.Sc.
Edwin van Wijngaarden, Ph.D., M.Sc.

VanWijngaarden Lab

Epidemiology
Public Health Sciences
Environmental Medicine
Research Interest: Environmental and Neurologic Epidemiology: Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.