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Faculty

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Affiliated Faculty

Danielle Benoit, Ph.D.

Danielle Benoit, Ph.D.

Assistant Professor

Benoit Lab

Biomedical Engineering - Developing novel polymeric materials for drug and cell delivery to promote tissue regeneration or treat diseases, including toxicity resulting from the introduction of foreign substances to the body.

Deborah Cory-Slechta, Ph.D.

Deborah Cory-Slechta, Ph.D.

Professor

Cory-Slechta Lab

Environmental Medicine - Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.

Lisa DeLouise, Ph.D., M.P.D.

Lisa DeLouise, Ph.D., M.P.D.

Associate Professor

DeLouise Lab

Dermatology - Understanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.

David Dean, Ph.D.

David Dean, Ph.D.

Professor

Dean Lab

Pediatrics - Delineating mechanisms that control DNA-protein complexes’ traffic through the cytoplasm, entry to the nucleus, and targeting to specific domains, and application of this to treat pulmonary diseases.

Alison Elder, Ph.D.

Alison Elder, Ph.D.

Associate Professor

Elder Lab

Environmental Medicine - Defining the impact of inhaled ambient and workplace nano-/ultrafine particle-containing aerosols on the lung, cardiovascular system, and central nervous system, and defining the toxicological properties of the particles that are associated with a response.

Jacob Finkelstein, Ph.D.

Jacob Finkelstein, Ph.D.

Professor

Finkelstein Lab

Pediatrics - Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.

Steve Georas, M.D.

Steve Georas, M.D.

Professor

Georas Lab

Medicine - Defining the role of environmental exposures on innate and adaptive immunity in asthma and other chronic lung diseases, with an emphasis on how particulate matter and endocrine disruptors act as risk factors.

Scott Gerber, Ph.D.

Scott Gerber, Ph.D.

Assistant Professor

Gerber Lab

Surgery - Conducting basic tumor immunology research, and also studying how environmental agents promote onset and/or progression of cancer.

Gail Johnson, Ph.D

Gail Johnson, Ph.D

Professor

Johnson Lab

Anesthesiology - Defining molecular mechanisms of neurodegeneration, and regulation of cell death and survival processes in the central nervous system.

Todd Jusko, Ph.D.

Todd Jusko, Ph.D.

Assistant Professor
Department of Public Health Sciences - Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.

B. Paige Lawrence, Ph.D.

B. Paige Lawrence, Ph.D.

Professor

Lawrence Lab

Environmental Medicine - Delineating mechanisms by which environmental exposures during different life stages alter immune function; discovering how environmental factors modulate epigenetic programming of the developing immune system, and the consequences of these changes on susceptibility to infectious, allergic, or autoimmune disease later in life.

Ania Majewska, Ph.D.

Ania Majewska, Ph.D.

Associate Professor

Majewska Lab

Neuroscience - Understanding structural and functional changes that occur at the specialized junctions between neurons (synapses) that lead to changes in brain function, including pioneering use of imaging techniques to study the structure and function of single synapses in complex networks in the intact brain; using these tools to better understand fetal alcohol syndrome and other developmental exposures that affect the brain.

Margot Mayer-Pröschel, Ph.D.

Margot Mayer-Pröschel, Ph.D.

Associate Professor

Mayer-Pröschel Lab

Biomedical Genetics - Deciphering the impact of nutritional, toxicological, viral, and genetic insults, singly and in combination, on mammalian brain development and disease later in life.

Richard Miller, M.D.

Richard Miller, M.D.

Professor

Richard Miller Lab

Obstetrics & Gynecology - Determining the impact of maternal stress and other maternal factors on the birth outcomes and in the children.

Mark Noble, Ph.D.

Mark Noble, Ph.D.

Professor

Noble Lab

Biomedical Genetics - Discovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.

M. Kerry O'Banion, M.D., Ph.D.

M. Kerry O'Banion, M.D., Ph.D.

Professor

O'Banion-Olschowka Labs

Neuroscience - Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, understanding injury arising from brain exposure to radiation, and characterizing effects of particulate matter exposure on Alzheimer's pathology and brain injury caused by methamphetamine exposure.

Michael O'Reilly, Ph.D.

Michael O'Reilly, Ph.D.

Professor

O'Reilly Lab

Pediatrics - Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.

Richard Phipps, Ph.D.

Richard Phipps, Ph.D.

Professor

Phipps Lab

Environmental Medicine - Investigating how environmental factors shape diseases involving immune and inflammatory components, including platelets, B cells, and lipid mediators, defining abnormal inflammatory and wound healing responses in the eye and lung, delineating molecular signaling in fibroblasts.

Gloria Pryhuber, M.D.

Gloria Pryhuber, M.D.

Professor
Chair

Pryhuber Lab

Pediatrics - Delineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.

Christoph Pröschel, Ph.D.

Christoph Pröschel, Ph.D.

Associate Professor

Pröschel Lab

Biomedical Genetics - Defining roles of glial progenitor cells and astrocytes as critical modulators in responses to chemical exposure, injury, or stress; discovering how exogenous factors contribute to neurodegenerative diseases; and developing new approaches to treat traumatic injury and neurodegenerative diseases.

J. Edward Puzas, Ph.D.

J. Edward Puzas, Ph.D.

Professor

Puzas Lab

Orthopaedics - Deciphering the molecular signals that govern osteoporosis and arthritis, as well as cellular changes that contribute to difficulties such as the loosening of artificial joints, including defining how environmental toxins such as lead, play a role in bone and joint diseases.

Arshad Rahman, Ph.D.

Arshad Rahman, Ph.D.

Associate Professor

Arshad Rahman Lab

Pediatrics - Determining how exogenous agents change lung microvasculature permeability, leading to pulmonary inflammation.

Irfan Rahman, Ph.D.

Irfan Rahman, Ph.D.

Professor

Irfan Rahman Lab

Environmental Medicine - Defining effects of inhaled environmental tobacco smoke, e-cigarettes, flavoring chemicals, and water pipe smoke toxicants on mitochondrial function, exosomes, and epigenetic chromatin modifiers in lung cell senescence, oxidative stress, and inflammation.

Matthew Rand, Ph.D.

Matthew Rand, Ph.D.

Associate Professor

Rand Lab

Environmental Medicine - Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.

David Rich, Sc.D., M.P.H.

David Rich, Sc.D., M.P.H.

Associate Professor

Rich Lab

Department of Public Health Sciences - Examining associations between air pollution and cardiopulmonary and pregnancy outcomes, validating biomarkers that may explain associations and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposures.

Jacques Robert, Ph.D.

Jacques Robert, Ph.D.

Associate Professor

Robert Lab

Microbiology & Immunology - Using a comparative biology approach to advance immunotoxicology, leveraging the amphibian Xenopus and the pox-like ranavirus FV3, to address long-term effects of water pollutants on immune cell development and on antiviral immunity across the lifespan.

Patricia Sime, M.D.

Patricia Sime, M.D.

Professor

Sime Lab

Medicine - Conducting clinical and translational toxicology research focusing on the lung, from studies of silica and radiation in lung fibrosis, to the effects of biomass and cigarette smoke exposure on lung inflammation and resolution pathways, to identifying key pathophysiologic pathways and developing novel therapeutics for lung inflammation and fibrosis.

Martha Susiarjo, Ph.D.

Martha Susiarjo, Ph.D.

Assistant Professor

Susiarjo Lab

Environmental Medicine - Studying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.

David Topham, Ph.D.

David Topham, Ph.D.

Professor

Topham Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology - Conducting clinical and translational research on respiratory pathogens, immunity, and infectious disease, including the study of environmental factors that affect immune responses to influenza and vaccination, seeking new approaches to enhance immunity, reduce pathology, and prevent disease.

Edwin Van Wijngaarden, Ph.D., M.Sc.

Edwin Van Wijngaarden, Ph.D., M.Sc.

Professor

VanWijngaarden Lab

Epidemiology - Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.

Jacqueline Williams, Ph.D.

Jacqueline Williams, Ph.D.

Professor

Jacqueline Williams Lab

Environmental Medicine - Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.

Hugh Xia, M.Sc., Ph.D.

Hugh Xia, M.Sc., Ph.D.

Associate Professor

Xia Lab

Pharmacology & Physiology - Investigating the role of environmental toxins such as arsenic on the protein phosphatase-1, a regulator of synaptic plasticity and cognition.

Michael Zuscik, Ph.D.

Michael Zuscik, Ph.D.

Associate Professor

Zuscik Lab

Orthopaedics - Defining the impact of obesity on bone repair, the molecular and cellular impact of chemical substances, including lead and benzo(a)pyrene, elucidating the molecular basis for deleterious effects of cigarette smoke on bone fracture healing, and uncovering basic signaling pathways involved with Pb-induced bone loss.