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Faculty

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Affiliated Faculty

Xin Bi, Ph.D.

Xin Bi, Ph.D.

Associate Professor

Bi Lab

Biology - Chromatin-mediated regulation of gene expression in eukaryotes.

Dirk Bohmann, Ph.D.

Dirk Bohmann, Ph.D.

Professor

Bohmann Lab

Biomedical Genetics - The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease

Paul Brookes, Ph.D.

Paul Brookes, Ph.D.

Associate Professor

Brookes Lab

Anesthesiology - Mitochondria and free radicals in cardiac ischemia-reperfusion

Michael Bulger, Ph.D.

Michael Bulger, Ph.D.

Associate Professor

Bulger Lab

Pediatrics - Chromatin domains and long-range activation by enhancers

Scott Butler, Ph.D.

Scott Butler, Ph.D.

Associate Professor

Butler Lab

Microbiology & Immunology - Regulation of Gene Expression by Targeted Degradation of RNA

Gloria Culver, Ph.D.

Gloria Culver, Ph.D.

Professor
Chair

Culver Lab

Biology - Assembly of the <em>E. coli</em> 30S ribosomal subunit, which is essential for cellular growth, so as to understand how infections might be controlled through selective inhibition of specific assembly control points.

Ian Dickerson, Ph.D.

Ian Dickerson, Ph.D.

Associate Professor

Dickerson Lab

Neuroscience - Molecular mechanisms of neuropeptide signal transduction

Mark Dumont, Ph.D.

Mark Dumont, Ph.D.

Professor

Dumont Lab

Biochemistry & Biophysics - Signal transduction; membrane protein structure, yeast molecular biology

Dmitri Ermolenko, Ph.D.

Dmitri Ermolenko, Ph.D.

Assistant Professor

Ermolenko Lab

Biochemistry & Biophysics - Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.

Sina Ghaemmaghami, Ph.D.

Sina Ghaemmaghami, Ph.D.

Assistant Professor

Ghaemmaghami Lab

Biology - Molecular mechanisms of prion propagation and pathogenesis

David Goldfarb, Ph.D.

David Goldfarb, Ph.D.

Professor

Goldfarb Lab

Biology - Molecular mechanisms that control the exchange of molecules and information between the nucleus and cytoplasm

Vera Gorbunova, Ph.D.

Vera Gorbunova, Ph.D.

Professor

Gorbunova Lab

Biology - Mechanisms of aging and the role of DNA repair and genomic instability in the aging process.

Elizabeth Grayhack, Ph.D.

Elizabeth Grayhack, Ph.D.

Associate Professor

Grayhack Lab

Biochemistry & Biophysics - Role of the genetic code in regulating protein synthesis and mRNA metabolism in <em>Saccharomyces cerevisiae</em>.

Alan Grossfield, Ph.D.

Alan Grossfield, Ph.D.

Associate Professor

Grossfield Lab

Biochemistry & Biophysics - Investigating membranes and membrane proteins via computer simulation

Clara Kielkopf, Ph.D.

Clara Kielkopf, Ph.D.

Associate Professor

Kielkopf Lab

Biochemistry & Biophysics - Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.

Hartmut Land, Ph.D.

Hartmut Land, Ph.D.

Professor
Chair

Land Lab

Biomedical Genetics - Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism

Xin Li, Ph.D.

Xin Li, Ph.D.

Assistant Professor

Li Lab

Biochemistry & Biophysics - Small RNAs in germ cells; epigenetic inheritance; bioinformatics

Lynne Maquat, Ph.D.

Lynne Maquat, Ph.D.

Professor

Maquat Lab

Biochemistry & Biophysics - RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.

David Mathews, M.D., Ph.D.

David Mathews, M.D., Ph.D.

Associate Professor

Mathews Lab

Biochemistry & Biophysics - Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.

Margot Mayer-Pröschel, Ph.D.

Margot Mayer-Pröschel, Ph.D.

Associate Professor

Mayer-Pröschel Lab

Biomedical Genetics - Deciphering the impact of nutritional, toxicological, viral, and genetic insults, singly and in combination, on mammalian brain development and disease later in life.

Benjamin Miller, Ph.D.

Benjamin Miller, Ph.D.

Professor

Benjamin Miller Lab

Dermatology - Carbohydrate and protein recognition, molecular design, and biomolecular sensing

Joshua Munger, Ph.D.

Joshua Munger, Ph.D.

Associate Professor

Munger Lab

Biochemistry & Biophysics - Mechanisms of metabolic network manipulation induced by viral infection and oncogenic mutation.

Mitchell O'Connell, Ph.D.

Mitchell O'Connell, Ph.D.

Assistant Professor

O'Connell Lab

Biochemistry & Biophysics - Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Archibald Perkins, M.D., Ph.D.

Archibald Perkins, M.D., Ph.D.

Professor

Perkins Lab

Pathology & Laboratory Medicine - Genes that impact the development of leukemias and other human malignancies

Eric Phizicky, Ph.D.

Eric Phizicky, Ph.D.

Professor

Phizicky Lab

Biochemistry & Biophysics - tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

Elaine Sia, Ph.D.

Elaine Sia, Ph.D.

Associate Professor

Sia Lab

Biology - Mutagenesis and repair of the mitochondrial genome.

Harold Smith, Ph.D.

Harold Smith, Ph.D.

Professor

Smith Lab

Biochemistry & Biophysics - RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.

Laurie Steiner, M.D.

Laurie Steiner, M.D.

Assistant Professor
Professor

Steiner Lab

PediatricsMedicine - Pediatric Biomedical Research

Douglas Turner, Ph.D.

Douglas Turner, Ph.D.

Professor

Turner Lab

Chemistry - Biophysical chemistry of RNA folding/stacking using NMR; RNA-targeted therapeutics

Joseph Wedekind, Ph.D.

Joseph Wedekind, Ph.D.

Professor

Wedekind Lab

Biochemistry & Biophysics - Structure and function analysis of gene regulation by riboswitches and microRNAs as a basis for therapeutic development.

Peng Yao, Ph.D.

Peng Yao, Ph.D.

Assistant Professor

Yao Lab

Medicine - Pathophysiological function of microRNAs, RNA-binding proteins, and defects in protein synthesis in cardiovascular disease; RNA riboswitch-like mechanisms of gene regulation

Yi-Tao Yu, Ph.D.

Yi-Tao Yu, Ph.D.

Professor

Yu Lab

Biochemistry & Biophysics - RNA modification; pre-mRNA splicing; snRNP biogenesis; telomerase RNA modification and aging; nonsense-disease therapeutics.

Jiyong Zhao, Ph.D.

Jiyong Zhao, Ph.D.

Associate Professor

Zhao Lab

Biomedical Genetics - Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation

Jian Zhu, Ph.D.

Jian Zhu, Ph.D.

Assistant Professor

Zhu Lab

Microbiology & Immunology - Host-virus interactions, particularly for HIV and herpes viruses